Intracellular distribution and intracellular dynamics of a spin-labeled analogue of doxorubicin by fluorescence and EPR spectroscopy

Journal of Pharmaceutical Sciences

Volumn 87, Issue 3, 1998, Pages 321-325

  Rapoport, Natalya ^a   Pitina, Lubov ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE DERIVATIVE; DOXORUBICIN; RUBOXYL;

ARTICLE; CELL TRANSPORT; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA STRUCTURE; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG DNA BINDING; DRUG TRANSPORT; ELECTRON SPIN RESONANCE; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL;

EID: 0031923294     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js970271g     Document Type: Article

References (9)

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5. Emanuel, N. M.; Konovalova, N. P.; Povarov, L. S.; Shapiro, A. B.; Dyachkovskaya, R. F.; Suskina, V. I.; Denisova, L. K. 13-(1-oxyl-2,2,6,6-tetramethylpiperylidenyl-4)hydrozone rubomycin hydrochloride with a paramagnetic center and a method of producing same. US Patent 4,332,934, 1982.
6. Konovalova, N. P.; Dyachkovskaya, R. F.; Ganieva, L. K.; Volkova, L. M.; Lapshin, I. M.; Rudakov, B. Y.; Shaposhnikov, Y. G.; Shapiro, A. B. Subrenal capsule assay of human tumor hemosensitivity. Neoplasma 1991, 38, 275-284.
7. Emanuel, N. M.; Konovalova, N. P.; Dyachkovskaya, R. F. Potential anti-cancer agents - nitroxyl derivatives of Rubomicin. Neoplasma 1985, 32, 285-292.
8. Shapiro, A. B., personal communication, 1995.
9. Alakhov, V. Y.; Moskaleva, E. Y.; Batrakova, E.; Kabanov, A. V. Reversion of multidrug resistance of human ovarian carcinoma cells by Pluronic P85 block copolymer. Bioconjugate Chem. 1996, 7, 209-216.