Alterations in chromosome structure and variations in the inherent radiation sensitivity of human cells

Radiation Research

Volumn 149, Issue 4, 1998, Pages 319-324

  Schwartz, Jeffrey L ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER RADIOTHERAPY; CHROMOSOME BREAKAGE; CHROMOSOME STRUCTURE; DNA REPAIR; GENETIC TRANSCRIPTION; GENOME; HUMAN; HUMAN CELL; IONIZING RADIATION; PRIORITY JOURNAL; RADIOSENSITIVITY; TUMOR CELL LINE;

CHROMOSOME ABERRATIONS; CHROMOSOMES; DEOXYRIBONUCLEOPROTEINS; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; NUCLEAR MATRIX; RADIATION, IONIZING; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; X-RAYS;

EID: 0031922149     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579692     Document Type: Article

References (51)

1. R. R. Weichselbaum, J. Rotmensch, S. Ahmed-Swan and M. A. Beckett, Radiobiological characterization of 53 human tumor cell lines. Int. J. Radiat. Biol. 56, 553-560 (1989).
2. B. Fertil and E. P. Malaise, Intrinsic radiosensitivity of human cell lines is correlated with radioresponsiveness of human tumors: Analysis of 101 published survival curves. Int. J. Radiat. Oncol. Biol. Phys. 11, 1699-1707 (1985).
3. W. K. Dahlberg, J. B. Little, J. A. Fletcher, H. D. Suit and P. Okunieff, Radiosensitivity in vitro of human soft tissue sarcoma cell lines and skin fibroblasts derived from the same patients. Int. J. Radiat. Biol. 63, 191-198 (1993).
4. M. Anton, R. Nenutil, A. Rejthar, J. Kopecny, B. Ptackova and J. Zaloudik, DNA flow cytometry: A predictor of a high-risk group in cervical cancer. Cancer Detect. Prev. 21, 242-246 (1997).
5. D. M. Monasebian and J. D. Ruskin, The relation of radiosensitivity of hypopharyngeal squamous cell carcinoma to DNA ploidy. J. Oral Maxillofac. Surg. 54, 167-170 (1996).
6. J. L. Schwartz, R. Mustafi, M. A. Beckett, E. A. Czyzewski, E. Farhangi, D. J. Grdina, J. Rotmensch and R. R. Weichselbaum, Radiation-induced DNA double-strand break frequencies in human squamous cell carcinoma cell lines of different radiation sensitivities. Int. J, Radiat. Biol. 59, 1341-1352 (1991).
7. J. L. Schwartz, M. B. Cohen, J. Rotmensch, S. M. Giovanazzi and R. R. Weichselbaum, Faster repair of DNA double-strand breaks in radioresistant human tumor cells. Int. J. Radiat. Oncol. Biol. Phys. 15, 907-912 (1988).
8. J. L. Schwartz, R. Mustafi, M. A. Beckett and R. R. Weichselbaum, DNA double-strand break rejoining rates, inherent radiation sensitivity and human tumour response to radiotherapy. Br. J. Cancer 74, 37-42 (1996).
9. L. R. Kelland, S. M. Edwards and G. G. Steel, Induction and rejoining of DNA double-strand breaks in human cervix carcinoma cell lines of differing radiosensitivity. Radiat. Res. 116, 526-538 (1988).
10. M. I. Nunez, M. Villalobos, N. Olea, M. T. Valenzuela, V. Pedraza, T. J. McMillan and J. M. Ruiz de Almodovar, Radiation-induced DNA double-strand break rejoining in human tumour cells. Br. J. Cancer 71, 311-316 (1995).
11. A. M. Cassoni, T. J. McMillan, J. H. Peacock and G. G. Steel, Differences in the level of DNA double-strand breaks in human tumour cell lines following low dose-rate irradiation. Eur. J. Cancer 28A, 1610-1614 (1992).
12. R. Wurm, N. G. Burnet, N. Duggal, J. R. Yarnold and J. H. Peacock, Cellular radiosensitivity and DNA damage in primary human fibroblasts. Int. J. Radiat. Oncol. Biol. Phys. 30, 625-633 (1994).
13. J. L. Schwartz and A. T. M. Vaughan, Association between DNA/chromosome break rejoining rates, chromatin structure alter- ations and radiation sensitivity in human tumor cell lines. Cancer Res, 49, 5054-5057 (1989).
14. P. L. Olive, DNA organization affects cellular radiosensitivity and detection of initial DNA strand breaks. Int. J. Radiat. Biol. 62, 389-396 (1992).
15. J. L. Schwartz and A. T. M. Vaughan, DNA-nuclear matrix interactions and ionizing radiation sensitivity. Environ. Mol. Mutagen. 22, 231-233 (1993).
16. J. L. Roti Roti, W. D. Wright and Y. C. Taylor, DNA loop structure and radiation response. In Advances in Radiation Biology, Vol. 17 (J. T. Lett and W. K. Sinclair, Eds.), pp. 227-259. Academic Press, San Diego, 1993.
17. A. E. Milner, D. J. Gordon, B. M. Turner and A. T. M. Vaughan, A correlation between DNA-nuclear matrix binding and relative radiosensitivity in two human squampus cell carcinoma cell lines. Int. J. Radiat. Biol. 63, 13-20 (1993).
18. J. S. Bedford, Sublethal damage, potentially lethal damage and chromosomal aberrations in mammalian cells exposed to ionizing radiations. Int. J. Radiat. Oncol. Biol. Phys. 21, 1457-1469 (1991).
19. A. V. Carrano, Chromosome aberrations and radiation-induced cell death. I. Transmission and survival parameters of aberrations. Mutat. Res. 17, 341-353 (1973).
20. J. S. Bedford, J. B. Mitchell, H. G. Griggs and M. A. Bender, Radiation-induced cellular reproductive death and chromosome aberrations. Radiat. Res. 76, 573-586 (1978).
21. S. J. Grote, G. P. Joshi, S. H. Revell and C. A. Shaw, Observations of radiation-induced chromosome fragment loss in live mammalian cells in culture, and its effect on colony forming ability. Int. J. Radiat. Biol. 39, 395-408 (1981).
22. J. L. Schwartz, The radiosensitivity of the chromosomes of the cells of human squamous cell carcinoma cells. Radiat. Res. 129, 96-101 (1992).
23. J. L. Schwartz, The role of constitutive and inducible processes in the response of human squamous cell carcinoma cell lines to ionizing radiation. Radiat. Res. 138 (Suppl.), S37-S39 (1994).
24. J. L. Schwartz and R. Jordan, Selective elimination of human lymphoid cells with unstable chromosome aberrations by p53-dependent apoptosis. Carcinogenesis 18, 201-205 (1997).
25. 2-phase cell cycle checkpoint control is associated with increased frequencies of unrejoined chromosome breaks in human tumor cells. Radiat. Res. 146, 139-143 (1996).
26. R. Warters, Radiation-induced apoptosis in a murine T-cell hybridoma. Cancer Res. 52, 883-890 (1992).
27. W. G. Nelson and M. B. Kastan, DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathways. Mol. Cell Biol. 14, 1815-1823 (1994).
28. D. D. Ager, J. W. Phillips, E. A. Columna, R. A. Winegar and W. F. Morgan, Analysis of restriction enzyme-induced DNA double-strand breaks in Chinese hamster ovary cells by pulsed-field gel electrophoresis: Implications for chromosome damage. Radiat. Res. 128, 150-156 (1991).
29. I. R. Radford, The level of induced DNA double-strand breakage correlates with cell killing after X-irradiation, Int. J. Radiat. Biol. 48, 45-54 (1985).
30. I. R. Radford, Evidence for a general relationship between the induced level of DNA double-strand breakage and cell-killing after X-irradiation of mammalian cells. Int. J. Radiat. Biol. 49, 611-620 (1986).
31. T. J. McMillan, A. M. Cassoni, S. M. Edwards, A. Holmes and J. H. Peacock, The relationship of DNA double-strand break induction to radiosensitivity in human tumour cell lines. Int. J. Radiat. Biol. 58, 427-438 (1990).
32. M. N. Cornforth and J. S. Bedford, Ionizing radiation damage and its early development in chromosomes. In Advances in Radiation Biol- ogy, Vol. 17 (J. T. Lett and W. K. Sinclair, Eds.), pp. 423-496. Academic Press, San Diego, 1993.
33. A. J. Giaccia, J. L. Schwartz, J. Shieh and J. M. Brown, The use of asymmetric-field inversion gel electrophoresis to predict tumor cell radiosensitivity. Radiother. Oncol. 24, 231-238 (1992).
34. S. J. Whitaker, Y. C. Ung and T. J. McMillan, DNA double-strand break induction and rejoining as determinants of human tumour cell radiosensitivity. A pulsed-field gel electrophoresis study. Int. J. Radiat. Biol. 67, 7-18 (1995).
35. P. L. Olive, J. P. Banáth and H. S. MacPhail, Lack of a correlation between radiosensitivity and DNA double-strand break induction or rejoining in six human tumor cell lines. Cancer Res. 54, 3939-3946 (1994).
36. M. F. Smeets, E. H. Mooren and A. C. Begg, Radiation-induced DNA damage and repair in radiosensitive and radioresistant human tumour cells measured by field inversion gel electrophoresis. Int. J. Radiat. Biol. 63, 703-713 (1993).
37. R. K. Sachs, A. M. Chen and D. J. Brenner, Proximity effects in the production of chromosome aberrations by ionizing radiation. Int. J. Radiat. Biol. 71, 1-19 (1997).
38. S. Wolff, The repair of X-ray induced chromosome aberrations in stimulated and unstimulated human lymphocytes. Mutat. Res. 15, 435-444 (1972).
39. J. L. Roti Roti and W. D. Wright, Visualization of DNA loops in nucleoids from HeLa cells: Assays for DNA damage and repair. Cytometry 8, 461-467 (1987).
40. M. Löbrich, B. Rydberg and P. K. Cooper, Repair of x-ray-induced DNA double-strand breaks in specific Not I restriction fragments in human fibroblasts: Joining of correct and incorrect ends. Proc. Natl. Acad. Sci. USA 92, 12050-12054 (1995).
41. R. S. Malyapa, W. D. Wright, Y. C. Taylor and J. L. Roti Roti, DNA supercoiling changes and nuclear matrix-associated proteins: Possible role in oncogene-mediated radioresistance. Int. J. Radiat. Oncol. Biol. Phys. 35, 963-973 (1996).
42. G. Iliakis, G. E. Pantelias and R. Seaner, Effect of arabinofuranosyladenine on radiation-induced chromosome damage in plateau-phase CHO cells measured by premature chromosome condensation: Implications for repair and fixation of α-PLD. Radiat. Res. 114, 361-378 (1988).
43. K. J. Pienta, A. W. Partin and D. S. Coffey, Cancer as a disease of DNA organization and dynamic cell structure. Cancer Res. 49, 2525-2532 (1989).
44. J. Bode, Y. Kohwi, L. Dickinson, T. Joh, D. Klehr, C. Mielke and T. Kohwi-Shigematsu, Biological significance of unwinding capability of nuclear matrix-associating DNAs. Science 255, 195-197 (1992).
45. T. Kohwi-Shigematsu and Y. Kohwi, Torsional stress stabilizes extended base unpairing in suppressor sites flanking immunoglobulin heavy chain enhancer. Biochemistry 29, 9551-9560 (1990).
46. M. W. Leonard and R. K. Patient, Evidence for torsional stress in transcriptionally activated chromatin. Mol. Cell Biol. 11, 6128-6138 (1991).
47. T. Jenuwein, W. C. Forrester, L. A. Fernandez-Herrero, G. Lalbie, M. Dull and R. Grosschedl, Extension of chromatin accessibility by nuclear matrix attachment regions. Nature 385, 269-272 (1997).
48. F. J. Iborra, A. Pombo, D. A. Jackson and P. R. Cook, Active RNA polymerases are localized within discrete transcription "factories" in human nuclei. J. Cell Sci. 109, 1427-1436 (1996).
49. V. A. Bohr, Gene specific DNA repair. Carcinogenesis 12, 1983-1992 (1991).
50. S. A. Leadon and P. K. Cooper, Preferential repair of ionizing radiation-induced damage in the transcribed strand of an active human gene is defective in Cockayne syndrome. Proc. Natl. Acad. Sci. USA 90, 10499-10503 (1993).
51. J. F. Ward, The complexity of DNA damage: Relevance to biological consequences. Int. J. Radiat. Biol. 66, 427-432 (1994).