Angiocytotoxic therapy in human non-small cell lung cancer cell lines: Advantage of combined effects of TNP-470 and SN-38

Acta Oncologica

Volumn 37, Issue 1, 1998, Pages 85-90

  Satoh, Hiroaki ^a   Ishikawa, Hiroichi ^a   Fujimoto, Mitsuo ^a   Fujiwara, Masachika ^a   Yamashita, Yuko T ^a   Yazawa, Takuya ^a   Ohtsuka, Morio ^a   Hasegawa, Shizuo ^a   Kamma, Hiroshi ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; CAMPTOTHECIN DERIVATIVE; CYTOTOXIC AGENT; FUMAGILLOL CHLOROACETYLCARBAMATE; TETRAZOLIUM;

ANGIOGENESIS; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CELL PROLIFERATION; DOSE RESPONSE; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; MINIMUM INHIBITORY CONCENTRATION; PRIORITY JOURNAL;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CAMPTOTHECIN; CARCINOMA, NON-SMALL-CELL LUNG; CELL DIVISION; CYCLOHEXANES; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; HUMANS; LUNG NEOPLASMS; SESQUITERPENES; TUMOR CELLS, CULTURED;

EID: 0031918499     PISSN: 0284186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/028418698423221     Document Type: Article

References (21)

1. Ingber D, Fujita T, Kishimoto S, et al. Synthetic analogues of fumugillin that inhibit angiogenesis and suppress tumour growth. Nature 1990; 348: 555-7.
2. Kunimoto T, Nitta K, Tanaka T, et al. Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1 -piperidono]carbonyloxy-camp-tothecin, a new water-soluble derivative of camptothecin. against murine tumors. Cancer Res 1987; 47: 5944-7.
3. Kaneda N, Nagata H, Furuta T, Yakokura T, Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse. Cancer Res 1990; 50: 1715-20.
4. Endo K, Kamma H, Ogata T. Two murine monoclonal antibodies against human lung cancer-associated antigens. Cancer Res 1986; 46: 6369-73.
5. Satoh H, Kamma H, Ogata T, Hasegawa S. Local production of plasminogen activator inhibitor-1 in carcinomatous pleuritis. Acta Oncol 1994; 33: 710-1.
6. Yanase T, Tamura M, Fujita K, Kodama S, Tanaka K. Inhibitory effect of angiogenesis inhibitor TNP-470 on tumor growth and metastasis of human cell lines in vitro and in vivo. Cancer Res 1993; 53: 2566-70.
7. Yamaoka M, Yamamoto T, Ikeyama S, Sudo K, Fujita T. Angiogenesis inhibitor TNP-470 (AGM-1470) potently inhibits the tumor growth of hormone-independent human breast and prostate carcinoma cell lines. Cancer Res 1993; 53: 5233-6.
8. Mosman T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxic assays. J Immunol Methods 1983; 65: 53-63.
9. Okano T, Okhuma T, Holland JF, Koeffler HP, Jui H. Effects of harringtonine in combination with activicin. Adriamycin. L-asparaginase, cytosine arabinoside. dexamethasone, fluorouracil, or methotrexate on human acute myelogenous leukemia cell line LG-1. Invest New Drugs 1983; 1: 145-50.
10. Kano Y, Suzuki K, Akutsu M, et al. Effects of CPT-11 in combination with other anti-cancer agents in culture. Int J Cancer 1992; 50: 604-10.
11. Tsai C, Shiao SH, Frey CM, et al. Combination cytotoxic effects of cis-diamminedichloro-platinum(II) and 5-fluorouracil with and without leukovorin against human non-small cell lung cancer cell lines. Cancer Res 1993; 53: 1079-84.
12. Figg WD, Pluda JM, Lush RM, et al. The pharmacokinetics of TNP-470, a new angiogenesis inhibitor. Pharmacotherapy 1997; 17: 91-7.
13. Levy T, Kudelka A, Verschraegen CF, et al. A phase 1 study of TNP-470 administrated to patients with advanced squamous cell cancer of the cervix (Abstract No. 1140). Proc Am Assoc Cancer Res 1996; 37.
14. Kusaka M, Sudo K, Mutsutani E, et al. Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470). Br J Cancer 1994; 69: 212-6.
15. Tanaka T, Konno H, Matsuda I, Nakamura S, Baba S, Prevention of hepatic metastasis of human colon cancer by angiogenesis inhibitor TNP-470. Cancer Res 1995; 55: 836-9.
16. Parangi S, O'Reilly M, Christofori G, Holmgren L, Grosfeld J, Hanahan D. Antiangiogenic therapy of transgenic mice impairs de novo tumor growth. Proc Natl Acad Sci USA 1996; 93: 2002-7.
17. Holmgren L, O'Reilly MS, Folkman J. Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nat Med 1995; 1: 149-53.
18. Teicher BA, Holden SA, Ara G, et al. Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents. Int J Cancer 1994; 57: 920-5.
19. Kato T, Sato K, Kakinuma H, Masuda Y. Enhanced suppression of tumor growth by combination of angiogenesis inhibitor O-(chloroacetyl-carbamoyl) fumagillol (TNP-470) and cytyotoxic agents in mice. Cancer Res 1994; 54: 5143-7.
20. Hsiang YH, Hertzberg R, Hecht S, Liu LF. Comptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase 1. J Biol Chem 1985; 260: 14873-8.
21. Wang JC. DNA topoisomerases. Ann Rev Biochem 1985; 54: 665-97.