메뉴 건너뛰기




Volumn 8, Issue 1, 1998, Pages 67-75

In vitro evaluation of fotemustine as a potential agent for limb perfusion in melanoma

Author keywords

Adenovirus; Cell cycle; Fotemustine; Melanoma; Methyl transferase; Resistance

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; ALKYLATING AGENT; CHLOROETHYLNITROSOUREA; DACARBAZINE; FOTEMUSTINE; MELPHALAN; N METHYL N(1) NITRO N NITROSOGUANIDINE; NITROSOGUANIDINE; UNCLASSIFIED DRUG;

EID: 0031917959     PISSN: 09608931     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008390-199802000-00012     Document Type: Article
Times cited : (6)

References (41)
  • 1
    • 0026606598 scopus 로고
    • Systemic chemotherapy for malignant melanoma
    • Coates AS. Systemic chemotherapy for malignant melanoma. World J Surg 1992; 16: 277-281.
    • (1992) World J Surg , vol.16 , pp. 277-281
    • Coates, A.S.1
  • 2
    • 0027938199 scopus 로고
    • Regional chemotherapy for melanoma. A 35-year experience
    • Krementz ET, Carter RD, Sutherland CM, et al. Regional chemotherapy for melanoma. A 35-year experience. Ann Surg 1994; 220: 520-534.
    • (1994) Ann Surg , vol.220 , pp. 520-534
    • Krementz, E.T.1    Carter, R.D.2    Sutherland, C.M.3
  • 3
    • 0023927780 scopus 로고
    • Regional isolation perfusion in melanoma of the limbs; accomplishments, unsolved problems, future
    • Kroon BB. Regional isolation perfusion in melanoma of the limbs; accomplishments, unsolved problems, future. Eur J Surg Oncol 1988; 14: 101-110.
    • (1988) Eur J Surg Oncol , vol.14 , pp. 101-110
    • Kroon, B.B.1
  • 4
    • 0025353844 scopus 로고
    • Therapy for cutaneous melanoma: An update
    • Ho VC, Sober AJ. Therapy for cutaneous melanoma: an update. J Am Acad Dermatol 1990; 22: 159-176.
    • (1990) J Am Acad Dermatol , vol.22 , pp. 159-176
    • Ho, V.C.1    Sober, A.J.2
  • 5
    • 0025515282 scopus 로고
    • Long-term results of a randomized trial of hyperthermic limb perfusion (HLP) with chemotherapy for extremity melanoma
    • Monson JR, Donohue JH. Long-term results of a randomized trial of hyperthermic limb perfusion (HLP) with chemotherapy for extremity melanoma. World J Surg 1990; 14: 845-846.
    • (1990) World J Surg , vol.14 , pp. 845-846
    • Monson, J.R.1    Donohue, J.H.2
  • 6
    • 0027940288 scopus 로고
    • Melphalan uptake, hyperthermic synergism and drug resistance in a human cell culture model for the isolated limb perfusion of melanoma
    • Clark J, Grabs AJ, Parsons PG, et al. Melphalan uptake, hyperthermic synergism and drug resistance in a human cell culture model for the isolated limb perfusion of melanoma. Melanoma. Res 1994; 4: 365-370.
    • (1994) Melanoma. Res , vol.4 , pp. 365-370
    • Clark, J.1    Grabs, A.J.2    Parsons, P.G.3
  • 7
    • 0025774686 scopus 로고
    • Sensitivity and resistance in human metastatic melanoma to the new chloroethylnitrosourea anti-tumor drug fotemustine
    • Schallreuter KU, Wood JM. Sensitivity and resistance in human metastatic melanoma to the new chloroethylnitrosourea anti-tumor drug fotemustine. Biochim Biophys Acta 1991; 1096: 277-283.
    • (1991) Biochim Biophys Acta , vol.1096 , pp. 277-283
    • Schallreuter, K.U.1    Wood, J.M.2
  • 8
    • 0027255607 scopus 로고
    • Long-term complete remissions in patients with disseminated melanoma treated by fotemustine and dacarbazine
    • Oliver V, Aliaga A, Lopez Lopez JJ, et al. Long-term complete remissions in patients with disseminated melanoma treated by fotemustine and dacarbazine. EurJ Cancer 1993; 29: 287.
    • (1993) EurJ Cancer , vol.29 , pp. 287
    • Oliver, V.1    Aliaga, A.2    Lopez Lopez, J.J.3
  • 9
    • 0027161605 scopus 로고
    • Phase II study of fotemustine as second-line treatment after failure of immunotherapy in metastatic renal cell carcinoma
    • Lasset C, MerroucheY, Negrier S, et al. Phase II study of fotemustine as second-line treatment after failure of immunotherapy in metastatic renal cell carcinoma. Cancer Chemother Pharmacol 1993; 32: 329-331.
    • (1993) Cancer Chemother Pharmacol , vol.32 , pp. 329-331
    • Lasset, C.1    Merrouche, Y.2    Negrier, S.3
  • 10
    • 0025878868 scopus 로고
    • Phase II study of fotemustine in recurrent supratentorial malignant gliomas
    • Frenay M, Giroux B, Khoury S, et al. Phase II study of fotemustine in recurrent supratentorial malignant gliomas. EurJ Cancer 1991; 27: 852-856.
    • (1991) EurJ Cancer , vol.27 , pp. 852-856
    • Frenay, M.1    Giroux, B.2    Khoury, S.3
  • 11
    • 0026655673 scopus 로고
    • Fotemustine: An overview of its clinical activity in disseminated malignant melanoma
    • Khayat D, Avril MF, Gerard B, et al. Fotemustine: an overview of its clinical activity in disseminated malignant melanoma. Melanoma Res 1992; 2: 147-151.
    • (1992) Melanoma Res , vol.2 , pp. 147-151
    • Khayat, D.1    Avril, M.F.2    Gerard, B.3
  • 12
    • 0027461143 scopus 로고
    • Fotemustine - An advance in the treatment of metastatic malignant melanoma
    • Merimsky O, Inbar M, Gerard B, Chaitchik S. Fotemustine - an advance in the treatment of metastatic malignant melanoma. Melanoma Res 1992; 2: 401-406.
    • (1992) Melanoma Res , vol.2 , pp. 401-406
    • Merimsky, O.1    Inbar, M.2    Gerard, B.3    Chaitchik, S.4
  • 13
    • 0025035726 scopus 로고
    • Base sequence specificity of three 2-chloroethylnitrosoureas
    • Briscoe WT, Anderson SR, May HE. Base sequence specificity of three 2-chloroethylnitrosoureas. Biochem Pharmacol 1990; 40: 1201-1209.
    • (1990) Biochem Pharmacol , vol.40 , pp. 1201-1209
    • Briscoe, W.T.1    Anderson, S.R.2    May, H.E.3
  • 14
    • 0023027829 scopus 로고
    • Formation of cyclic adducts in nucleic acids by the haloethylnitrosoureas
    • Ludlum DB. Formation of cyclic adducts in nucleic acids by the haloethylnitrosoureas. IARC Sci Publ 1986; 137-146.
    • (1986) IARC Sci Publ , pp. 137-146
    • Ludlum, D.B.1
  • 15
    • 0022273478 scopus 로고
    • 6-(2-chloroethyl)guanine mediates the biological effects of chloroethylnitrosoureas
    • 6-(2-chloroethyl)guanine mediates the biological effects of chloroethylnitrosoureas. Environ Health Perspect 1985; 62: 119-126.
    • (1985) Environ Health Perspect , vol.62 , pp. 119-126
    • Bodell, W.J.1    Aida, T.2    Berger, M.S.3
  • 16
    • 0019957212 scopus 로고
    • Formation of the cross-link 1-(N3-deoxycytidyl),2(N1-deoxyguanosinyl) ethane in DNA treated with N,N′-bis(2-chloroethyl)-N-nitrosourea
    • Tong WP, Kirk MC, Ludlum DB. Formation of the cross-link 1-(N3-deoxycytidyl),2(N1-deoxyguanosinyl) ethane in DNA treated with N,N′-bis(2-chloroethyl)-N-nitrosourea. Cancer Res 1982; 42: 3102-3105.
    • (1982) Cancer Res , vol.42 , pp. 3102-3105
    • Tong, W.P.1    Kirk, M.C.2    Ludlum, D.B.3
  • 18
    • 0025195404 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase: Regulation and importance in response to alkylating carcinogenic and therapeutic agents
    • 6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents. Cancer Res 1990; 50: 6119-6129.
    • (1990) Cancer Res , vol.50 , pp. 6119-6129
    • Pegg, A.E.1
  • 20
    • 0021894988 scopus 로고
    • 6-methylguanine-DNA methyltransferase in cell survival, mutagenesis and carcinogenesis
    • 6-methylguanine-DNA methyltransferase in cell survival, mutagenesis and carcinogenesis. Mutation Res 1985; 145: 1-16.
    • (1985) Mutation Res , vol.145 , pp. 1-16
    • Yarosh, D.B.1
  • 22
    • 0023159821 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase becomes covalently bound to DNA containing 1,3-bis(2-chloroethyl)-1-nitrosourea-induced precursors of interstrand cross-links
    • 6-alkylguanine-DNA alkyltransferase becomes covalently bound to DNA containing 1,3-bis(2-chloroethyl)-1-nitrosourea-induced precursors of interstrand cross-links. Biochem Biophys Res Commun 1987; 142: 341-347.
    • (1987) Biochem Biophys Res Commun , vol.142 , pp. 341-347
    • Brent, T.P.1    Smith, D.G.2    Remack, J.S.3
  • 23
    • 0025811927 scopus 로고
    • Nitrosoureas lomustine, carmustine and fotemustine induced hepatotoxic perturbations in rats: Biochemical, morphological and flow cytometry studies
    • Laquerriere A, Raguenez-Viotte G, Paraire M, et al. Nitrosoureas lomustine, carmustine and fotemustine induced hepatotoxic perturbations in rats: biochemical, morphological and flow cytometry studies. Eur J Cancer 1991; 27: 630-638.
    • (1991) Eur J Cancer , vol.27 , pp. 630-638
    • Laquerriere, A.1    Raguenez-Viotte, G.2    Paraire, M.3
  • 24
    • 0028887352 scopus 로고
    • Combination of computerized morphonuclear and multivariate analyses to characterize in vitro the antineoplastic effect of alkylating agents
    • Pauwels O, Stassi G, Kiss R. Combination of computerized morphonuclear and multivariate analyses to characterize in vitro the antineoplastic effect of alkylating agents. J Pharmacol Toxicol Methods 1995; 33: 35-45.
    • (1995) J Pharmacol Toxicol Methods , vol.33 , pp. 35-45
    • Pauwels, O.1    Stassi, G.2    Kiss, R.3
  • 25
    • 0024803881 scopus 로고
    • Cytotoxicity and DNA damaging effects of a new nitrosourea, fotemustine, diethyl-1-[3-(2-chloroethyl)-3-nitrosoureido] ethylphosphonate-S10036
    • Tapiero H, Yin MB, Catalin J, et al. Cytotoxicity and DNA damaging effects of a new nitrosourea, fotemustine, diethyl-1-[3-(2-chloroethyl)-3-nitrosoureido] ethylphosphonate-S10036. Anticancer Res 1989; 9: 1617-1622.
    • (1989) Anticancer Res , vol.9 , pp. 1617-1622
    • Tapiero, H.1    Yin, M.B.2    Catalin, J.3
  • 26
    • 0022510514 scopus 로고
    • Cross-sensitivity of methylating agents, hydroxyurea, and methotrexate in human tumor cells of the Mer phenotype
    • Maynard K, Parsons PG. Cross-sensitivity of methylating agents, hydroxyurea, and methotrexate in human tumor cells of the Mer phenotype. Cancer Res 1986; 46: 5009-5013.
    • (1986) Cancer Res , vol.46 , pp. 5009-5013
    • Maynard, K.1    Parsons, P.G.2
  • 27
    • 0028044724 scopus 로고
    • Chemosensitivity testing of human malignant melanoma. A retrospective analysis of clinical response and in vitro drug sensitivity
    • Schadendorf D, Worm M, Algermissen B, Kohlmus CM, Czarnetzki BM. Chemosensitivity testing of human malignant melanoma. A retrospective analysis of clinical response and in vitro drug sensitivity. Cancer 1994; 73: 103-108.
    • (1994) Cancer , vol.73 , pp. 103-108
    • Schadendorf, D.1    Worm, M.2    Algermissen, B.3    Kohlmus, C.M.4    Czarnetzki, B.M.5
  • 28
    • 0026208721 scopus 로고
    • New aspects in the pathophysiology of cutaneous melanoma: A review of the role of thioproteins and the effect of nitrosoureas. Melanoma Res 199 cutaneous melanoma: A review of the role of thioproteins and the effect of nitrosoureas
    • Schallreuter KU, Wood JM. New aspects in the pathophysiology of cutaneous melanoma: a review of the role of thioproteins and the effect of nitrosoureas. Melanoma Res 199 cutaneous melanoma: a review of the role of thioproteins and the effect of nitrosoureas. Melanoma Res 1992; 1: 159-167.
    • (1992) Melanoma Res , vol.1 , pp. 159-167
    • Schallreuter, K.U.1    Wood, J.M.2
  • 29
    • 0029877012 scopus 로고    scopus 로고
    • Molecular mechanisms of toxic effects of fotemustine in rat hepatocytes and subcellular rat liver fractions
    • Brakenhoff JP, Commandeur JN, Wormhoudt LW, et al. Molecular mechanisms of toxic effects of fotemustine in rat hepatocytes and subcellular rat liver fractions. Carcinogenesis 1996; 17: 715-724.
    • (1996) Carcinogenesis , vol.17 , pp. 715-724
    • Brakenhoff, J.P.1    Commandeur, J.N.2    Wormhoudt, L.W.3
  • 30
    • 0027476839 scopus 로고
    • Phase 1 pharmacokinetics study of high dose fotemustine and its metabolite 2-chloroethanol in patients with high grade gliomas
    • Tranchand B, Lucas C, Biron P, et al. Phase 1 pharmacokinetics study of high dose fotemustine and its metabolite 2-chloroethanol in patients with high grade gliomas. Cancer Chemotber Pharmacol 1993; 32: 46-52.
    • (1993) Cancer Chemotber Pharmacol , vol.32 , pp. 46-52
    • Tranchand, B.1    Lucas, C.2    Biron, P.3
  • 31
    • 0021361091 scopus 로고
    • Comparison of virus reactivation, DNA base damage, and cell cycle effects in autologous human melanoma cells resistant to methylating agents
    • Hayward IP, Parsons PG. Comparison of virus reactivation, DNA base damage, and cell cycle effects in autologous human melanoma cells resistant to methylating agents. Cancer Res 1984; 44: 55-58.
    • (1984) Cancer Res , vol.44 , pp. 55-58
    • Hayward, I.P.1    Parsons, P.G.2
  • 32
    • 0024401123 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase activity, and reactivation of methylated adeno-virus 5 and herpes simplex virus type 1 in human melanoma cell lines
    • 6-alkylguanine-DNA alkyltransferase activity, and reactivation of methylated adeno-virus 5 and herpes simplex virus type 1 in human melanoma cell lines. Cancer Res 1989; 49: 4813-4817.
    • (1989) Cancer Res , vol.49 , pp. 4813-4817
    • Maynard, K.1    Parsons, P.G.2    Cerny, T.3
  • 33
    • 0017346890 scopus 로고
    • In situ detection of Mycoplasma contamination in cell culture by fluorescent Hoechst 33258 Stain
    • Chen TR. In situ detection of Mycoplasma contamination in cell culture by fluorescent Hoechst 33258 Stain. Exp Cell Res 1977; 104: 255-262.
    • (1977) Exp Cell Res , vol.104 , pp. 255-262
    • Chen, T.R.1
  • 34
    • 0021259836 scopus 로고
    • Treatment-time dependence of melphalan resistance and DNA crosslinking in human melanoma cells
    • Parsons PG. Treatment-time dependence of melphalan resistance and DNA crosslinking in human melanoma cells. Cancer Res 1984; 44: 2773-2778.
    • (1984) Cancer Res , vol.44 , pp. 2773-2778
    • Parsons, P.G.1
  • 35
    • 0029007870 scopus 로고
    • DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines
    • Branch P, Hampson R, Karran P. DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines. Cancer Res 1995; 55: 2304-2309.
    • (1995) Cancer Res , vol.55 , pp. 2304-2309
    • Branch, P.1    Hampson, R.2    Karran, P.3
  • 36
    • 0027502938 scopus 로고
    • Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage
    • Branch P, Aquilina G, Bignami M, et al. Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage. Nature 1993; 362: 652-654.
    • (1993) Nature , vol.362 , pp. 652-654
    • Branch, P.1    Aquilina, G.2    Bignami, M.3
  • 37
    • 0026451201 scopus 로고
    • Hepatic intra-arterial infusion of fotemustine: Pharmacokinetics
    • Fety R, Lucas C, Solere P, et al. Hepatic intra-arterial infusion of fotemustine: pharmacokinetics. Cancer Chemother Pharmacol 1992; 31: 118-122.
    • (1992) Cancer Chemother Pharmacol , vol.31 , pp. 118-122
    • Fety, R.1    Lucas, C.2    Solere, P.3
  • 38
    • 0002538947 scopus 로고
    • Antineoplastic agents
    • Goodman L, Gilman AG, eds. New York: Macmillan
    • Calabrasi P, Chabner A. Antineoplastic agents. In: Goodman L, Gilman AG, eds. The Pharmacological Basis of Therapeutics, New York: Macmillan, 1991, Vol 2, 1209-1223.
    • (1991) The Pharmacological Basis of Therapeutics , vol.2 , pp. 1209-1223
    • Calabrasi, P.1    Chabner, A.2
  • 39
    • 0023472241 scopus 로고
    • A regioselective mechanism for mutagenesis and oncogenesis caused by alkylnitrosourea: A sequence specific DNA alkylation
    • Buckley NA. A regioselective mechanism for mutagenesis and oncogenesis caused by alkylnitrosourea: a sequence specific DNA alkylation. J Am Chem Soc 1987; 109: 7918-7920.
    • (1987) J Am Chem Soc , vol.109 , pp. 7918-7920
    • Buckley, N.A.1
  • 40
    • 0023760379 scopus 로고
    • Structure activity relations of 2-chloroethyl nitrosoureas 2. Kinetic evidence for a novel mechanism for the cytotoxicity of important DNA cross-linking reactions of 2 (chloroethyl)nitrosoureas
    • Buckley NA, Brent TP. Structure activity relations of 2-chloroethyl nitrosoureas 2. Kinetic evidence for a novel mechanism for the cytotoxicity of important DNA cross-linking reactions of 2 (chloroethyl)nitrosoureas. J Am Chem Soc 1988; 110: 7520.
    • (1988) J Am Chem Soc , vol.110 , pp. 7520
    • Buckley, N.A.1    Brent, T.P.2
  • 41
    • 0027460206 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase in human peripheral blood mononuclear cells
    • 6-alkylguanine-DNA alkyltransferase in human peripheral blood mononuclear cells. Br J Cancer 1993; 67: 216-221.
    • (1993) Br J Cancer , vol.67 , pp. 216-221
    • Lee, S.M.1    Thatcher, N.2    Dougal, M.3    Margison, G.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.