The synthesis of aminimide-containing azole antifungals

Journal of Heterocyclic Chemistry

Volumn 35, Issue 1, 1998, Pages 193-199

  Abel, Mark D ^a   Hewgill, Randy T ^a   Malczyk, Katherine J ^a   Micetich, Ronald G ^a   Daneshtalab, Mohsen ^a  

^a NAEJA Pharmaceutical Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DIMETHYLHYDRAZINE; ACETIC ACID ETHYL ESTER; ANTIFUNGAL AGENT; EPOXIDE; IMIDAZOLE DERIVATIVE; METHANOL;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA; CRYPTOCOCCUS; CRYSTAL STRUCTURE; DIASTEREOISOMER; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; X RAY CRYSTALLOGRAPHY;

EID: 0031916537     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570350137     Document Type: Article

References (9)

1. M. Daneshtalab, unpublished results.
2. E. Peisach, D. Casebier, S. L. Gallion, P. Furth, G. A. Petsko, J. C. Hogan Jr. and D. Ringe, Science, 269, 66 (1995).
3. E. E. Rutenber, F. McPhee, A. P. Kaplan, S. L. Gallion, J. C. Hogan Jr., C. S. Craik and R. M. Stroud, Bioorg. Med. Chem., 4, 1545 (1996).
4. W. J. McKillip, E. A. Sedor, B. M. Culbertson and S. Wawzonek, Chem. Rev., 73, 255 (1973).
5. S. Wawzonek, Ind. Eng. Chem. Prod. Res. Dev., 19, 338 (1980).
6. R. C. Slagel, J. Org. Chem., 33, 1374 (1968).
7. K. Richardson, U.K. Patent 2 099 818 A (1982);
8. Chem. Abstr., 99, 38467q (1983).
9. Reference method for broth dilution antifungal susceptibility testing for yeasts. Proposed standard M27-P. National Committee for Clinical Laboratory Standards, 1992.