The butadiene metabolite, 1,2:3,4-diepoxybutane, induces micronuclei but is only weakly mutagenic at lacI in the Big Blue® Rat2 lacI transgenic cell line

Environmental and Molecular Mutagenesis

Volumn 31, Issue 1, 1998, Pages 32-40

  Saranko, Christopher J ^a,b   Recio, Leslie ^b,c  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b CIIT CENTERS FOR HEALTH RESEARCH   (United States)

^c NONE   (United States)

Author keywords

1,2:3,4 diepoxybutane; Big Blue Rat2 cell line; LacI transgene; Micronuclei; Mutation

Indexed keywords

BUTADIENE DIEPOXIDE;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; FIBROBLAST; METABOLITE; MICRONUCLEUS; MUTAGENICITY; MUTATION; NONHUMAN; POINT MUTATION; RAT; TRANSGENE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BACTERIAL PROTEINS; CELL LINE; CYTOCHALASIN B; EPOXY COMPOUNDS; ESCHERICHIA COLI PROTEINS; MICRONUCLEUS TESTS; MUTAGENS; POINT MUTATION; RATS; REPRESSOR PROTEINS;

EID: 0031914499     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(1998)31:1<32::AID-EM5>3.0.CO;2-D     Document Type: Article

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