Developmental and aging changes of Bak expression in the human brain

Brain Research

Volumn 783, Issue 1, 1998, Pages 167-170

  Obonai, Toshimasa ^a   Mizuguchi, Masashi ^a,b   Takashima, Sachio ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Aging; Apoptosis; Development; Immunohistochemistry; Neuron; Western blotting

Indexed keywords

AGING; APOPTOSIS; ARTICLE; BRAIN TISSUE; CEREBELLUM; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NERVE CELL NECROSIS; PRIORITY JOURNAL; PURKINJE CELL;

ADOLESCENT; ADULT; AGED; AGING; AMINO ACID SEQUENCE; APOPTOSIS; BRAIN; CHILD; CHILD, PRESCHOOL; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, BCL-2; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; INFANT, NEWBORN; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA;

EID: 0031912844     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)01361-9     Document Type: Article

References (21)

1. Chittenden T., Flemington C., Houghton A.B., Ebb R.G., Gallo G.J., Elangovan B., Chinnadurai G., Lutz R.J. A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions. EMBO J. 14:1995;5589-5596.
2. Chittenden T., Harrington E.A., O'Connor R., Flemington C., Lutz R.J., Evan G.I., Guild B.C. Induction of apoptosis by the Bcl-2 homolougue Bak. Nature. 374:1995;733-736.
3. Cowan W.M., Fawcett J.W., O'Leary D.D.M., Stanfield B.B. Regressive events in neurogenesis. Science. 225:1984;1258-1265.
4. Ellis H.M., Yuan J., Horvitz H.R. Mechanism and function of cell death. Annu. Rev. Cell. Biol. 7:1991;663-698.
5. Farrow S.N., White J.H.M., Martinou I., Raven T., Pun K.-T., Grinham C.J., Martinou J.-C., Brown R. Cloning of a bcl-2 homolougue by interaction with adenovirus E1B 19K. Nature. 374:1995;731-733.
6. Kiefer M.C., Brauer M.J., Powers V.C., Wu J.J., Umansky S.R., Tomei L.D., Barr P.J. Modulation of apoptosis by the widely distributed Bcl-2 homolougue Bak. Nature. 374:1995;736-739.
7. Krajewski S., Krajewska M., Reed J.C. Immunohistochemical analysis of in vivo patterns of Bak expression, a proapoptotic member of the bcl-2 protein family. Cancer Res. 56:1996;2849-2855.
8. LeBrun D.P., Warnke R.A., Cleary M.L. Expression of bcl-2 in fetal tissues suggests a role in morphogenesis. Am. J. Pathol. 142:1993;743-753.
9. Migheli A., Cavalla P., Marino S., Schiffer D. A study of apoptosis in normal and pathologic nervous tissue after in situ end-labelling of DNA strand breaks. J. Neuropathol. Exp. Neurol. 53:1994;606-616.
10. Mizuguchi M., Ikeda K., Asada M., Mizutani S., Kamoshita S. Expression of Bcl-2 protein in murine neural cells in culture. Brain Res. 649:1994;197-202.
11. Mizuguch M., Morimatsu Y. Histopathological study of allobar holoprosencephaly: 1. abnormal laminar architecture of the telencephalic cortex. Acta Neuropathol. 78:1989;176-182.
12. Mizuguchi M., Sohma O., Takashima S., Ikeda K., Yamada M., Shiraiwa N., Ohta S. Immunochemical and immunohistochemical localization of Bcl-x protein in the rat central nervous system. Brain Res. 712:1996;281-286.
13. Mizuguchi M., Takashima S., Kakita A., Yamada M., Ikeda K. Lissencephaly gene product. Localization in the central nervous system and loss of immunoreactivity in Miller-Dieker syndrome. Am. J. Pathol. 147:1995;1142-1151.
14. Novack D.V., Korsmeyer S.J. Bcl-2 protein expression during murine development. Am. J. Pathol. 145:1994;61-73.
15. Oppenheim R.W. Cell death during development of the nervous system. Annu. Rev. Neurosci. 14:1991;453-501.
16. Paradis E., Douillard H., Koutroumanis M., Goodyer C., LeBranc A. Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons. J. Neurosci. 16:1996;7533-7539.
17. Reed J.C. Bcl-2 and the regulation of programmed cell death. J. Cell. Biol. 124:1994;1-6.
18. Sattler M., Liang H., Nettesheim D., Meadows R.P., Harlan J.E., Eberstadt M., Yoon H.S., Shuker S.B., Chang B.S., Minn A.J., Thompson C.B., Fesik S.W. Structure of Bcl-XL-Bak peptide complex: recognition between regulators of apoptos. Science. 275:1997;983-986.
19. Smale G., Nichols N.R., Brady D.R., Finch C.E., Horton W.E. Jr. Evidence for apoptotic cell death in Alzheimer's disease. Exp. Neurol. 133:1995;225-230.
20. Sohma O., Mizuguchi M., Takashima S., Yamada M., Ikeda K., Ohta S. High expression of Bcl-x protein in the developing human cerebellar cortex. J. Neurosci. Res. 43:1996;175-182.
21. Vaux D.L. Toward an understanding of the molecular mechanisms of physiological cell death. Proc. Natl. Acad. Sci. USA. 90:1993;786-789.