ONO-4007, an antitumor lipid A analog, induces tumor necrosis factor-α production by human monocytes only under primed state: Different effects of ONO-4007 and lipopolysaccharide on cytokine production

Journal of Pharmacology and Experimental Therapeutics

Volumn 284, Issue 1, 1998, Pages 189-195

  Matsumoto, Norihito ^a,b   Aze, Yoshiya ^a   Akimoto, Akira ^a   Fujita, Tsuneo ^a  

^a ONO PHARMACEUTICAL CO   (Japan)

^b NONE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; COLONY STIMULATING FACTOR 1; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPID A DERIVATIVE; LIPOPOLYSACCHARIDE; SODIUM 2 DEOXY 2 [(9 PHENYLNONANOYLOXY)TETRADECANOYL]AMINO 3 O (9 PHENYLNONANOYL) DEXTRO GLUCOPYRANOSE 4 SULFATE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL;

ADULT; ANTINEOPLASTIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKIN-1; INTERLEUKIN-12; INTERLEUKIN-6; LIPID A; LIPOPOLYSACCHARIDES; MONOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031912318     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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