Proton inhibition of GABA-activated current in rat primary sensory neurons

Pflugers Archiv European Journal of Physiology

Volumn 435, Issue 4, 1998, Pages 539-545

  Zhai, Jin ^a   Peoples, Robert W ^b   Li, Chaoying ^b  

^a Columbia University ^*  (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

GABA receptor; Ion channel; Patch clamp recording; pH; Sensory neuron

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; ION CHANNEL;

ANIMAL TISSUE; ARTICLE; CHANNEL GATING; CHLORIDE CURRENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; MALE; MEMBRANE POTENTIAL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SENSORY NERVE CELL; SPINAL GANGLION;

ANIMALS; CHLORIDE CHANNELS; GABA ANTAGONISTS; GANGLIA, SPINAL; HYDROGEN-ION CONCENTRATION; MALE; MEMBRANE POTENTIALS; NEURONS, AFFERENT; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA;

EID: 0031909552     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050550     Document Type: Article

References (28)

1. Bevan S, Yeats J (1991) Protons activate a cation conductance in a subpopulation of rat dorsal root ganglion neurones. J Physiol (Lond) 433:145-161
2. Bullock J (1991) Acid-base physiology. In: Bullock J, Boyle J, Wang MB (eds) Physiology. Williams and Wilkins, Baltimore, pp 257-301
3. Busa W B (1986) Mechanisms and consequences of pH-mediated cell regulation. Annu Rev Physiol 48:389-402
4. Curtis DR (1978) Pre- and non-synaptic activities of GABA and related amino acids in the mammalian nervous system. In: Fonnum F (ed) Amino acids as chemical transmitters. Plenum, New York, pp 55-86
5. Curtis DR, Lodge D, Bornstien JC, Peet MJ (1981) selective effect of (-)-baclofen on soinal synaptic transmission in the cat. Exp Brain Res 58:333-337
6. Dawson RMC, Elliott DC, Elliott WH, Jones KM (1986) Data for biochemical research. Clarendon, Oxford
7. Franks NP, Lieb WR (1994) Molecular and cellular mechanisms of anesthesia. Nature 367:607-614
8. Gallagher JP, Nakamura J, Shinnock-Gallagher P (1983) The effects of temperature, pH and Cl pump inhibitors on GABA responses recorded from cat dorsal root ganglia. Brain Res 267:249-259
9. + modulation of NMDA receptor-mediated EPSCs revealed by carbonic anhydrase inhibition in rat hippocampus. J Physiol (Lond) 478: 373-378
10. Gruol DL, Barker JL, Huang LYM, Macdonald JF, Smith TG (1980) Hydrogen ions have multiple effects on the excitability of cultured mammalian neurons. Brain Res 183:247-252
11. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth F (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 391:89-100
12. A receptor subtypes expressed in dorsal root ganglia of the adult rat. Soc Neurosci Abstr 17:797
13. A receptor is associated with the receptor subunit composition. J Physiol (Lond) 492:431-443
14. Krishtal OA, Pidoplichko VI (1980) A receptor for protons in the nerve cell membrane. Neuroscience 5:2325-2327
15. Levy RA (1977) The role of GABA in primary afferent depolarization. Prog Neurobiol 9:211-267
16. 2+ in rat nodose ganglion neurons. J Neurophysiol 76:3048-3058
17. Li C, Peoples R W, Weight FF (1996) Acid pH augments excitatory action of ATP on a dissociated mammalian sensory neuron. Neuroreport 7:2151-2154
18. Li C, Peoples RW, Weight FF (1997) Enhancement of ATP-activated current by protons in dorsal root ganglion neurons. Pflügers Arch 433:446-454
19. Lin F, Stevens CF (1994) Both open and closed NMDA receptor channels desensitize. J Neurosci 14:2153-2160
20. Lindahl O (1974) Pain - a general chemical explanation. Adv Neurol 4:45-47
21. McCarty DJ, Phelps P, Pyenson H (1966) Crystal-induced inflammation in canine joints. J Exp Med 124:99-114
22. Petersen M, LaMotte RH (1993) Effect of protons on the inward current evoked by capsaicin in isolated dorsal root ganglion cells. Pain 54:37-42
23. A receptors on rat cerebellum granule cells. Neuroscience 61:833-837
24. Taira T, Smirnov S, Voipio J, Kaila K (1993) Intrinsic proton modulation of excitatory transmission in rat hippocampal slices. Neuroreport 4:93-96
25. +. Proc Natl Acad Sci USA 87:6445-6449
26. Traynelis SF, Cull-Candy SG (1990) Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons. Nature 345:347-350
27. Victor RG, Bertocci LA, Pryor SL, Nunnally RL (1988) Sympathetic nerve discharge is coupled to muscle cell pH during exercise in humans. J Clin Invest 82:1301-1305
28. A-receptor-activated current in dorsal root ganglion neurons freshly isolated from adult rats. J Neurophysiol 64:57-63