Molecular basis of α-tocopherol control of smooth muscle cell proliferation

BioFactors

Volumn 7, Issue 1-2, 1998, Pages 3-14

  Azzi, Angelo ^a   Aratri, Elisabetta ^a   Boscoboinik, Daniel ^a   Clément, Sophie ^a   Özer, Nesrin K ^b   Ricciarelli, Roberta ^c   Spycher, Stefan ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b MARMARA UNIVERSITY   (Turkey)

^c UNIVERSITY OF GENOA   (Italy)

Author keywords

Cell proliferation; Oxidative stress; Protein kinase C; Protein phosphatase; Vascular smooth muscle cell; Vitamin E; tocopherol

Indexed keywords

ALPHA TOCOPHEROL; BETA TOCOPHEROL; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CELL PROLIFERATION; CONTROLLED STUDY; DEPHOSPHORYLATION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VITRO STUDY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; VASCULAR SMOOTH MUSCLE;

ANIMALIA;

EID: 0031907537     PISSN: 09516433     EISSN: None     Source Type: Journal    
DOI: 10.1002/biof.5520070102     Document Type: Article

References (25)

1. A. Azzi, D. Boscoboinik, E. Chatelain, N.K. Özer and B. Stäuble, d-alpha-tocopherol control of cell proliferation, Mol. Aspects Med. 14 (1993), 265-271.
2. A. Azzi, D. Boscoboinik, D. Marilley, N.K. Özer, B. Stäuble and A. Tasinato, Vitamin E: A sensor and an information transducer of the cell oxidation state, Am. J. Clin. Nutr. 62(Suppl.) (1995), 1337S-1346S.
3. R. Ross, The pathogenesis of atherosclerosis: a perspective for the 1990s, Nature 362 (1993), 801-809.
4. E.W. Raines and R. Ross, Smooth muscle cells and the pathogenesis of the lesions of atherosclerosis, Br. Heart J. 69 (1993), S30-S37.
5. K.F. Gey, The antioxidant hypothesis of cardiovascular disease: epidemiology and mechanisms, Biochem. Soc. Trans. 18 (1990), 1041-1045.
6. E.B. Rimm, M.J. Stampfer, A. Ascherio, E. Giovannucci, G.A. Colditz and W.C. Willett, Vitamin E consumption and the risk of coronary heart disease in men, New Engl. J. Med. 328 (1993), 1450-1456.
7. M.J. Stampfer, C.H. Hennekens, J.E. Manson, G.A. Colditz, B. Rosner and W.C. Willett, Vitamin E consumption and the risk of coronary disease in women, New Engl. J. Med. 328 (1993), 1444-1449.
8. N.G. Stephens, A. Parsons, P.M. Schofield, F. Kelly, K. Cheeseman, M.J. Mitchinson and M.J. Brown, Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS), Lancet 347 (1996), 781-786.
9. A. Azzi, D. Boscoboinik and C. Hensey, The protein kinase C family, Eur. J. Biochem. 208 (1992), 547-557.
10. A.C. Newton, Protein kinase C: Structure, function, and regulation, J. Biol. Chem. 270 (1995), 28495-28498.
11. A. Tasinato, D. Boscoboinik, G.M. Bartoli, P. Maroni and A. Azzi, d-α-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties, Proc. Natl. Acad. Sci. USA 92 (1995), 12 190-12 194.
12. F. Bornancin and P.J. Parker, Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase C-α, Curr. Biol. 6 (1996), 1114-1123.
13. E.M. Dutil, L.M. Keranen, A.A. De Paoli-Roach and A.C. Newton, In vivo regulation of protein kinase C by transphosphorylation followed by autophosphorylation, J. Biol. Chem. 269 (1994), 29359-29362.
14. D. Boscoboinik, A. Szewczyk, C. Hensey and A. Azzi, Inhibition of cell proliferation by alpha-tocopherol. Role of protein kinase C, J. Biol. Chem. 266 (1991), 6188-6194.
15. D.O. Boscoboinik, E. Chatelain, G.M. Bartoli, B. Stäuble and A. Azzi, Inhibition of protein kinase C activity and vascular smooth muscle cell growth by d-alpha-tocopherol, Biochim. Biophys. Acta 1224 (1994), 418-426.
16. D. Boscoboinik, N.K. Özer, U. Moser and A. Azzi, Tocopherols and 6-hydroxy-chroman-2-carbonitrile derivatives inhibit vascular smooth muscle cell proliferation by a nonantioxidant mechanism, Arch. Biochem. Biophys. 318 (1995), 241-246.
17. A.C. Chan and K. Tran, The uptake of (R,R,R)-alpha-tocopherol by human endothelial cells in culture, Lipids 25 (1990), 17-21.
18. D.R. Alexander, J.D. Graves, S.C. Lucas, D.A. Cantrell and M.J. Crumpton, A method for measuring protein kinase C activity in permeabilized T-lymphocytes by using peptide substrates. Evidence for multiple pathways of kinase activation, Biochem. J. 268 (1990), 303-308.
19. C. Borner, I. Filipuzzi, M. Wartmann, U. Eppenberger and D. Fabbro, Biosynthesis and posttranslational modifications of protein kinase C in human breast cancer cells, J. Biol. Chem. 264 (1989), 13 902-13 909.
20. G. Martiny Baron, M.G. Kazanietz, H. Mischak, P.M. Blumberg, G. Kochs, H. Hug, D. Marme and C. Schachtele, Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976, J. Biol. Chem. 268 (1993), 9194-9197.
21. Y. Shapira, R. Amit and E. Rachmilewitz, Vitamin E deficiency in Werdnig-Hoffmann disease, Ann. Neurol. 10 (1981), 266-268.
22. J.H. Sung, A.R. Mastri and S.H. Park, Axonal dystrophy in the gracile nucleus in children and young adults. Reappraisal of the incidence and associated diseases, J. Neuropathol. Exp. Neurol. 40 (1981), 37-45.
23. W. Baumgartner, K. Frese and I. Elmadfa, Neuroaxonal dystrophy associated with vitamin E deficiency in two Haflinger horses, J. Comp. Pathol. 103 (1990), 114-119.
24. C. Hubner, H.A. Lehr, R. Bodlaj, B. Finckh, K. Oexle, S.L. Marklund, K. Freudenberg, A. Kontush, A. Speer, K. Terwolbeck, T. Voit and A. Kohlschutter, Wheat kernel ingestion protects from progression of muscle weakness in mdx mice, an animal model of duchenne muscular dystrophy, Pediatr. Res. 40 (1996), 444-449.
25. G. Orndahl, G. Grimby, A. Grimby, G. Johansson and L. Wilhelmsen, Functional deterioration and selenium-vitamin E treatment in myotonic dystrophy. A placebo-controlled study, J. Intern. Med. 235 (1994), 205-210.