Changes in sputum composition during sputum induction in healthy and asthmatic subjects

Clinical and Experimental Allergy

Volumn 28, Issue 3, 1998, Pages 284-292

  Holz, O ^a   Jorres R A ^a   Koschyk, S ^a   Speckin, P ^a   Welker, L ^a   Magnussen, H ^a  

^a KRANKENHAUS GROSSHANSDORF   (Germany)

Author keywords

Airway inflammation; Eosinophil cationic protein; Eosinophils; Macrophages; Neutrophils

Indexed keywords

ALLERGEN; EOSINOPHIL CATIONIC PROTEIN; METHACHOLINE;

ADULT; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; EOSINOPHIL; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; INFLAMMATION; MACROPHAGE; MALE; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN CONTENT; PROVOCATION TEST; SPUTUM ANALYSIS;

ADMINISTRATION, INHALATION; ADULT; ASTHMA; BLOOD PROTEINS; CELL COUNT; EOSINOPHIL GRANULE PROTEINS; EOSINOPHILS; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; INFLAMMATION MEDIATORS; L-LACTATE DEHYDROGENASE; MACROPHAGES, ALVEOLAR; MALE; NEUTROPHILS; REPRODUCIBILITY OF RESULTS; RIBONUCLEASES; SALINE SOLUTION, HYPERTONIC; SPUTUM; VITAL CAPACITY;

EID: 0031905407     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.1998.00243.x     Document Type: Article

References (17)

1. Fahy JV, Liu J, Wong H, Boushey HA. Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis 1993; 147:1126-31.
2. Gibson PG, Girgis-Garbado A, Morris MM et al. Cellular characteristics of sputum from patients with asthma and chronic bronchitis. Thorax 1989; 44:693-9.
3. Efthimiadis A, Pizzichini MMM, Pizzichini E et al. The influence of cell viability and squamous epithelial cell contamination on the reliability of sputum differential cell counts. Am J Respir Crit Care Med 1995; 151:A384 (abstract).
4. Fahy JV, Liu J, Boushey HA. Reproducibility of measurements made in induced sputum from asthmatic subjects. Am J Respir Crit Care Med 1995; 151:A384.
5. Pizzichini E, Morris MM, Efthimiadis A et al. Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid phase measurements. Am J Respir Crit Care Med 1996; 154:308-17.
6. In't Veen JCCM, de Gouw HWFM, Smits HH et al. Repeatability of cellular and soluble markers of inflammation in induced sputum from patients with asthma. Eur Respir J 1996; 9:2441-7.
7. Fahy JV, Wong H, Liu J, Boushey HA. Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects. Am J Respir Crit Care Med 1995; 152:53-8.
8. Thompson AB, Daughton D, Robbins RA et al. Intraluminal airway inflammation in chronic bronchitis. Am Rev Respir Dis 1989; 140:1527-37.
9. Popov T, Gottschalk R, Kolendowicz R et al. The evaluation of a cell dispersion method of sputum examination. Clin Exp Allergy 1994;24:778-83.
10. International Consensus Report on diagnosis and treatment of asthma. Eur Respir J 1992; 5:601-41.
11. Quanjer PhH. (ed.) Standardized lung function testing. Eur Respir J 1993; 6 (Suppl. 16):5-40.
12. Bonnet R, Jörres R, Heitmann U, Magnussen H. Circadian rhythm in airway responsiveness and airway lone in patients with mild asthma. J Appl Physiol 1991; 71:1598-605.
13. Pin I, Gibson PG, Kolendowicz R et al. Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 1992; 47:25-9.
14. Fleiss LF. The design and analysis of clinical experiments. John Wiley & Sons, New York 1986; 1-31.
15. Lam S, Leriche JC, Kijek K, Phillips D. Effect of bronchial lavage volume on cellular and protein recovery. Chest 1985; 88:856-9.
16. Rankin JA, Marcy T, Rochester CL, Sussman J, Smith S, Buckley P, Lee D. Human airway macrophages. Am Rev Respir Dis 1992; 145:928-33.
17. Van Vyve T, Chanez P, Lacoste JY, Bousquet J, Michel FB, Godard P. Comparison between bronchial and alveolar samples of bronchoalveolar lavage fluid in asthma. Chest 1992; 102:356-61.