Novel genes that upregulate the Proteus mirabilis flhDC master operon controlling flagellar biogenesis and swarming

Molecular Microbiology

Volumn 29, Issue 3, 1998, Pages 741-751

  Dufour, Alain ^a,b   Furness, Richard B ^a   Hughes, Colin ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITÉ DE BRETAGNE SUD   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOGENESIS; CELL DIVISION; CELL STRUCTURE; CONSENSUS SEQUENCE; FLAGELLUM; GRAM NEGATIVE BACTERIUM; MUTANT; NEGATIVE FEEDBACK; OPEN READING FRAME; OPERON; PRIORITY JOURNAL; PROTEUS MIRABILIS;

BACTERIAL PROTEINS; BASE SEQUENCE; CHROMOSOMES, BACTERIAL; DNA, BACTERIAL; DNA-BINDING PROTEINS; ESCHERICHIA COLI PROTEINS; FLAGELLA; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; OPERON; PROTEUS MIRABILIS; TRANS-ACTIVATORS; UP-REGULATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MIRABILIS; NEGIBACTERIA; PROTEUS MIRABILIS;

EID: 0031904670     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1998.00967.x     Document Type: Article

References (41)

1. Adler, J., and Templeton, B. (1967) The effects of environmental conditions on the motility of Escherichia coli. J Gen Microbiol 46: 175-184.
2. Allison, C., and Hughes, C. (1991) Bacterial swarming: an example of prokaryotic differentiation and multicellular behaviour. Scientific Progress 75: 403-422.
3. Allison, C., Lai, H.-C., and Hughes, C. (1992) Co-ordinate expression of virulence genes during swarm-cell differentiation and population migration of Proteus mirabilis. Mol Microbiol 6: 1583-1591.
4. Altschul, S.F., Gish, W., Miller, W., Myers, E.W., and Lipman, D.J. (1990) Basic local alignment search tool. J Mol Biol 215: 403-410.
5. Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A., et al. (1988) Current Protocols in Molecular Biology. New York: John Wiley and Sons.
6. Belas, R., and Flaherty, D. (1994) Sequence and genetic analysis of multiple flagellin-encoding genes from Proteus mirabilis. Gene 128: 33-41.
7. Bertin, P., Terato, E., Lee, T.H., Lejeune, P., Colson, C., Danchin, A., et al. (1994) The H-NS protein is involved in the biogenesis of flagella in Escherichia coli. J Bacteriol 176: 5537-5540.
8. Blattner, F.R., Plunkett, III, G., Bloch, C.A., Perna, N.T., Burland, V., Riley, M., et al. (1997) The complete genome sequence of Escherichia coli K-12. Science 277: 1453-1474.
9. Devereux, J., Haeberli, P., and Smithies, O. (1984) A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res 12: 387-395.
10. Eberl, L., Christiansen, G., Molin, S., and Givskov, M. (1996) Differentiation of Serratia liquefaciens into swarm cells is controlled by the expression of the flhDC master operon. J Bacteriol 178: 554-559.
11. Feinberg, A.P., and Vogelstein, B. (1984) A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132: 6-13.
12. Fella, R., Frey, J., and Krisch, H. (1987) Interposon mutagenesis of soil and water bacteria: a family of DNA fragments designed for in vitro insertional mutagenesis of Gram-negative bacteria. Gene 52: 147-154.
13. Fleischmann, R.D., Adams, M.D., White, O., Clayton, R.A., Kirkness, E.F., Kerlavage, A.R., et al. (1995) Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science 269: 496-512.
14. Furness, R.B., Fraser, G.M., Hay, N.A., and Hughes, C. (1997) Negative feedback from a Proteus class II flagellum export defect to the flhDC master operon controlling cell division and flagellum assembly. J Bacteriol 179: 5585-5588.
15. BAD promoter. J Bacteriol 177: 4121-4130.
16. Gygi, D., Bailey, M.J., Allison, C., and Hughes, C. (1995) Requirement for FIhA in flagella assembly and swarm cell differentiation by Proteus mirabilis. Mol Microbiol 15: 761-769.
17. Gygi, D., Fraser, G., Dufour, A., and Hughes, C. (1997) A motile but non-swarming mutant of Proteus mirabilis lacks FlgN, a facilitator of FliC export and flagella assembly. Mol Microbiol 25: 597-604.
18. Hay, N.A., Tipper, D.J., Gygi, D., and Hughes, C. (1997) A non-swarming mutant of Proteus mirabilis lacks the Lrp global transcriptional regulator. J Bacteriol 176: 4741-4746.
19. Hughes, K.T., Gillen, K.L., Melinda, J.S., and Karlinsey, J.E. (1993) Sensing structural intermediates in bacterial flagellar assembly by export of a negative regulator. Science 262: 1277-1280.
20. Klein, P., Kanehisa, M., and Delisi, C. (1985) The detection and classification of membrane spanning proteins. Biochim Biophys Acta 815: 468-476.
21. Koronakis, V., and Hughes, C. (1988) Identification of the promoters directing in vivo expression of haemolysin in Proteus vulgaris and Escherichia coli. Mol Gen Genet 213: 99-104.
22. Koronakis, V., Cross, M., Senior, B., Koronakis, E., and Hughes, C. (1987) The secreted haemolysin of Proteus mirabilis, Proteus vulgaris and Morganella morganii are genetically related to each other and to the alpha-haemolysin of Escherichia coli. J Bacteriol 169: 1509-1515.
23. Kutsukake, K. (1997) Autogenous and global control of the flagellar master operon, flhD, in Salmonella typhimurium. Mol Gen Genet 254: 440-448.
24. Kutsukake, K., and Iino, T. (1994) Role of the FliA-FlgM regulatory system on the transcriptional control of the flagellar regulon and flagellar formation in Salmonella typhimurium. J Bacteriol 176: 3598-3605.
25. Li, C., Louise, C.J., Shi, W., and Adler, J. (1993) Adverse conditions which cause lack of flagella in Escherichia coli. J Bacteriol 175: 2229-2235.
26. Liu, X., and Matsumura, P. (1994) The FlhD/FlhC complex, a transcriptional activator of the Escherichia coli flagellar class II operons. J Bacteriol 176: 7345-7351.
27. Liu, X., and Matsumura, P. (1996) Differential regulation of multiple overlapping promoters in flagellar class II operons in Escherichia coli. Mol Microbiol 21: 613-620.
28. McCarthy, J.E.G., and Brimacombe, R. (1994) Prokaryotic translation: the interactive pathway leading to initiation. Trends Genet 10: 402-407.
29. Macnab, R.M. (1996) Flagella and motility. In Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology. Neidhardt, F.C., Ingraham, J.L., Low, K.B., Magasanik, B., Schaechter, M., and Umbarger, H.E. (eds). Washington, DC: American Society for Microbiology Press, pp. 123-145.
30. Miller, V.L., and Mekalanos, J.J. (1988) A novel suicide vector and its use in construction of insertion mutants: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR. J Bacteriol 170: 2575-2583.
31. F. Mol Microbiol 6: 3149-3157.
32. Pruß, B.M., and Matsumura, P. (1996) A regulator of the flagellar regulon of Escherichia coli, flhD also affects cell division. J Bacteriol 178: 668-674.
33. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
34. Sanger, F., Nicklen, S., and Coulson, R.A. (1977) DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74: 5463-5467.
35. Selby, C.P., and Sancar, A. (1993) Molecular mechanism of transcription-repair coupling. Science 260: 53-58.
36. Shi, W., Zhou, Y., Wild, J., Adler, J., and Gross, C.A. (1992) DnaK, DnaJ, and GrpE are required for flagellum synthesis in Escherichia coli. J Bacteriol 174: 6256-6263.
37. Shi, W., Li, C., Louise, C.J., and Adler, J. (1993) Mechanism of adverse conditions causing lack of flagella in Escherichia coli. J Bacteriol 175: 2236-2240.
38. Shin, S., and Park, C. (1995) Modulation of flagellar expression in Escherichia coli by acetyl phosphate and the osmoregulator OmpR. J Bacteriol 177: 4696-4702.
39. Swihart, K.G., and Welch, R.A. (1990) Cytotoxic activity of the Proteus hemolysin HpmA. Infect Immun 58: 1861-1869.
40. von Heinje, G. (1986) A new method for predicting signal cleavage sites. Nucleic Acids Res 14: 4683-4690.
41. Young, I.G., Rogers, B.L., Campbell, H.D., Jaworowski, A., and Shaw, D.C. (1981) Nucleotide sequence coding for the respiratory NADH dehydrogenase of Escherichia coli. UUG initiation codon. Eur J Biochem 116: 165-170.