Application of a novel method for subsequent evaluation of sinusoids and postsinusoidal venules after ischemia-reperfusion injury of rat liver

European Surgical Research

Volumn 30, Issue 4, 1998, Pages 252-258

  Kondo, T ^a   Okamoto, S ^a   Todoroki, T ^b   Hirano, T ^c   Schildberg, F W ^a   Messmer, K ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c NATL INST BIOSCI HUM TECHNOL   (Japan)

Author keywords

Intravital fluorescence microscopy; Ischemia reperfusion liver injury; Liver microcirculation; Repetitive observation of microvasculature

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; LEUKOCYTE; LIVER INJURY; LIVER ISCHEMIA; LIVER PERFUSION; LIVER SINUSOID; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; VENULE;

ANIMALS; CELL ADHESION; ISCHEMIA; LEUKOCYTES; LIVER CIRCULATION; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; VENULES;

EID: 0031903202     PISSN: 0014312X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000008584     Document Type: Article

References (16)

1. Vollmar B, Menger MD, Glasz J, Leiderer R, Messmer K: Impact of leukocyte-endothelial cell interaction in hepatic iscbemia-reperfusion injury. Am J Physiol 1994;267: G786-G793.
2. Vollmar B, Glasz J, Leiderer R, Post S, Menger MD: Hepatic microcirculatory perfusion failure is a determinant of liver dysfunction in warm ischemia-reperfusion. Am J Pathol 1994;145:1421-1431.
3. Vollmar B, Glasz J, Post S, Menger M: Role of microcirculatory derangements in manifestation of portal trial cross-clamping-induced hepatic reperfusion injury. J Surg Res 1996;60:49-54.
4. Vollmar B, Richter S, Menger MD: Leukocyte stasis in hepatic sinusoids. Am J Physiol 1996;270: G798-G803.
5. Chun K, Zhang J, Biewer J, Ferguson D, Clemens MG: Microcirculatory failure determines lethal hepatocyte injury in ischemic/reperfused rat livers. Shock 1994;1:3-9.
6. 2 treatment. Am J Physiol 1985;248:H804-H811.
7. Ferguson D, McDonagh P, Biewer J, Paidas C, Clemens M: Spatial relationship between leukocyte accumulation and microvascular injury during reperfusion following hepatic ischemia. Int J Microcirc Clin Exp 1993;12:45-60.
8. Koo A, Komatsu H, Tao G, Inoue M, Guth PH, Kaplowitz N: Contribution of no-reflow phenomenon to hepatic injury after ischemia-reperfusion: Evidence for a role for superoxide anion. Hepatology 1991;15: 507-514.
9. Menger M, Müller M, Friedl H, Trentz O, Messmer K: Ischemia-reperfusion injury of the liver: Role of neutrophils and xanthine oxidase: in Faist E, Meakins JL, Schildberg FW (eds): Host Defence Dysfunction in Trauma, Shock and Sepsis. New York, Springer, 1992. pp 499-503.
10. Zhang JX, Jones DV, Clemens MG: Effect of activation on neutrophil-induced hepatic microvascular injury in isolated rat liver. Shock 1994; 1.273-278.
11. Menger MD, Steiner D, Messmer K: Microvascular ischemia-reperfusion injury in striated muscle: Significance of 'no reflow'. Am J Physiol 1992;263:H1892-H1900.
12. Ames A, Wright RL, Kowada M, Thurston JM, Majno G: Cerebral ischemia. II. The no-reflow phenomenon. Am J Pathol 1968;52: 437-453.
13. Majno G, Ames A, Chiang J, Wright RL: No reflow after cerebral ischemia. Lancet 1967;ii:569-570.
14. Kloner RA, Ganote CE, Jennings RB: The 'no-reflow' phenomenon after temporary coronary occlusion in the dog. J Clin Invest 1974;54: 1496-1508.
15. Menger M, Lehr H, Messmer K: Role of oxygen radicals in the microcirculatory manifestations of postischemic injury. Klin Wochenschr 1991;69:1050-1055.
16. Koeppel T, Thies J, Lehmann T, Gebhard M, Herfarth C, Otto G, Post S: Improvement of hepatic microhemodynamics by N-acetylcysteine after warm ischemia. Eur Surg Res 1996;28.270-277.