Human cytomegalovirus glycoprotein H/glycoprotein L, complex modulates fusion-from-without

Journal of General Virology

Volumn 79, Issue 4, 1998, Pages 855-865

  Milne, Richard S B ^a,b   Paterson, David A ^a   Booth, James C ^a  

^a ST GEORGE S HOSPITAL   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENT DYE; MONOCLONAL ANTIBODY; VIRUS GLYCOPROTEIN;

ARTICLE; EMBRYO; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; MEMBRANE FUSION; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; VIRUS CELL INTERACTION; VIRUS PARTICLE;

EID: 0031902616     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-79-4-855     Document Type: Article

References (50)

1. Babic, N., Klupp, B. G., Makoschey, B., Karger, A., Flamand, A. & Mettenleiter, T. C. (1996). Glycoprotein gH of pseudorabies virus is essential for penetration and propagation in cell culture and in the nervous system of mice. Journal of General Virology 77, 2277-2285.
2. Baboonian, C., Blake, K., Booth, J. C. & Wiblin, C. N. (1989). Complement-independent neutralising monoclonal antibody with differential reactivity for strains of cytomegalovirus. Journal of Medical Virology 29, 139-145.
3. Bold, S., Ohlin, M., Garten, W. & Radsak, K. (1996). Structural domains involved in human cytomegalovirus glycoprotein B-mediated cell-cell fusion. Journal of General Virology 77, 2297-2302.
4. Booth, J. C., Beesley, J. E. & Stern, H. (1978). Syncytium formation caused by human cytomegalovirus in human embryonic lung fibroblasts. Archives of Virology 57, 143-152.
5. Britt, W. J. (1996). Vaccines against human cytomegalovirus: time to test. Trends in Microbiology 4, 34-38.
6. Chee, M. S., Bankier, A. T., Beck, S., Bohni, R., Brown, C. M., Cerny, R., Horsnell, T., Hutchinson, C. A., Kouzarides, T., Martignetti, J. A., Preddie, E., Satchwell, S. C., Tomlinson, P., Weston, K. M. & Barrell, B. G. (1990). Analysis of the protein coding content of the sequence of human cytomegalovirus strain AD169. Current Topics in Microbiology and Immunology 154, 125-169.
7. Cranage, M. P., Smith, G. L., Bell, S. E., Hart, H., Brown, C., Bankier, A. T., Tomlinson, P., Barrell, B. G. & Minson, T. C. (1988). Identification and expression of a human cytomegalovirus glycoprotein with homology to the Epstein-Barr virus BXLF2 product, varicella-zoster virus gpIII, and herpes simplex virus glycoprotein H. Journal of Virology 62, 1416-1422.
8. Desai, P. J., Schaffer, P. A. & Minson, A. C. (1988). Excretion of non-infectious virus particles lacking glycoprotein H by a temperature-sensitive mutant of herpes simplex virus type 1: evidence that gH is essential for virion infectivity. Journal of General Virology 69, 1147-1156.
9. Duus, K. M., Hatfield, C. & Grose, C. (1995). Cell surface expression and fusion by the varicella-zoster virus gH:gL glycoprotein complex : analysis by laser scanning confocal microscopy. Virology 210, 429-440.
10. Elek, S. D. & Stern, H. (1974). Development of a vaccine against mental retardation caused by cytomegalovirus infection in utero. Lancet i, 1-5.
11. Falconer, M. M., Gilbert, J. K., Roper, A. M., Greenberg, H. B. & Gavora, J. S. (1995). Rotavirus-induced fusion from without in tissue culture cells. Journal of Virology 69, 5582-5591.
12. Falke, D., Knoblich, A. & Müller, S. (1985). Fusion from without induced by herpes simplex virus type 1. Intervirology 24, 211-219.
13. Fernando, S., Pearce, M. J. & Booth, J. C. (1993). Lymphocyte responses and virus excretion as risk factors for intrauterine infection with human cytomegalovirus. Journal of Medical Virology 41, 108-113.
14. Forrester, A., Farrell, H., Wilkinson, G., Kaye, J., Davis-Poynter, N. & Minson, T. (1992). Construction and properties of herpes simplex virus type 1 with glycoprotein H coding sequences deleted. Journal of Virology 66, 341-348.
15. Garnett, H. M. (1979). Fusion of cytomegalovirus infected fibroblasts to form multinucleated giant cells. Journal of Medical Virology 3, 271-274.
16. Gompels, U. A. & Minson, A. C. (1989). Antigenic properties and cellular localization of herpes simplex virus glycoprotein H synthesized in a mammalian cell expression system. Journal of Virology 63, 4744-4755.
17. Graham, F. L. & van der Eb, A. J. (1974). A new technique for the assay of infectivity of adenovirus type 5 DNA. Virology 52, 456-467.
18. Gretch, D. R., Kari, B., Rasmussen, L., Gehrz, R. C. & Stinski, M. F. (1988). Identification and characterization of three distinct families of glycoprotein complexes in the envelopes of human cytomegalovirus. Journal of Virology 62, 875-881.
19. Huber, M. T. & Compton, T. (1997). Characterisation of a novel third member of the human cytomegalovirus glycoprotein H-glycoprotein L complex. Journal of Virology 71, 5391-5398.
20. Jacobs, S. C., Stephenson, J. R. & Wilkinson, G. W. G. (1992). High level expression of the tick-borne encephalitis virus NSl protein by using an adenovirus-based vector: protection elicited in a murine model. Journal of Virology 66, 2086-2095.
21. Kaye, J. F., Gompels, U. A. & Minson, A. C. (1992). Glycoprotein H of human cytomegalovirus (HCMV) forms a stable complex with the HCMV UL115 gene product. Journal of General Virology 73, 2693-2698.
22. Keay, S. & Baldwin, B. (1991). Anti-idiotype antibodies that mimic gp86 of human cytomegalovirus inhibit viral fusion but not attachment. Journal of Virology 65, 5124-5128.
23. Keay, S., Merigan, T. C. & Rasmussen, L. (1989). Identification of cell surface receptors for the 86-kilodalton glycoprotein of human cytomegalovirus. Proceedings of the National Academy of Sciences, USA 86, 10100-10103.
24. 2+], mediated by the 92·5-kDa putative cell membrane receptor for HCMV gp86. American Journal of Physiology 269 (Cell Physiology 38), C11-C21.
25. Li, L., Nelson, J. & Britt, W. J. (1997). Glycoprotein H-related complexes of human cytomegalovirus : identification of a third protein in the gCIII complex. Journal of Virology 71, 3090-3097.
26. Liu, D. X., Gompels, U. A., Foa-Tomasi, L. & Campadelli-Fiume, G. (1993). Human herpesvirus-6 glycoprotein H and L homologs are components of the gp100 complex and the gH external domain is the target for neutralizing monoclonal antibodies. Virology 197, 12-22.
27. McGrory, W. J., Bautista, D. S. & Graham, F. L. (1988). A simple technique for the rescue of early region 1 mutations into infectious human adenovirus type 5. Virology 163, 614-617.
28. Miller, N. M. & Hutt-Fletcher, L. M. (1988). A monoclonal antibody to glycoprotein gp85 inhibits fusion but not attachment of Epstein-Barr virus. Journal of Virology 62, 2366-2372.
29. Milne, R. S. B. (1996). The glycoprotein H/L complex of human cytomegalovirus: its role in the spread of infection. PhD thesis, University of London, UK.
30. Navarro, D., Paz, P., Tugizov, S., Topp, K., La Vail, J. & Pereira, L. (1993). Glycoprotein B of human cytomegalovirus promotes virion penetration into cells, transmission of infection from cell-to-cell, and fusion of infected cells. Virology 197, 143-158.
31. Nelson, P. N., Rawal, B. K., Boriskin, Y. S., Mathers, K., Powles, R. L., Steel, H. M., Tryhorn, Y. S., Butcher, P. D. & Booth, J. C. (1996). A polymerase chain reaction to detect a spliced late transcript of human cytomegalovirus in the blood of bone marrow transplant recipients. Journal of Virological Methods 56, 139-148.
32. Pachl, C., Probert, W. S., Hermsen, K. M., Masiarz, F. R., Rasmussen, L., Merigan, T. C. & Spaete, R. R. (1989). The human cytomegalovirus strain Towne glycoprotein H gene encodes glycoprotein gp86. Virology 169, 418-426.
33. Rasmussen, L. E., Nelson, R. M., Kelsall, D. C. & Merigan, T. C. (1984). Murine monoclonal antibody to a single protein neutralises the infectivity of human cytomegalovirus. Proceedings of the National Academy of Sciences, USA 81, 876-880.
34. Rasmussen, L., Resta, S. & Merigan, T. (1991). Human cytomegalovirus glycoprotein-receptor interactions. Transplantation Proceedings 23, 60-63.
35. Riddell, S. R., Rabin, M., Geballe, A. P., Britt, W. J. & Greenberg, P. D. (1991). Class I MHC-restricted CTL recognition of cells infected with HCMV does not require endogenous viral gene expression. Journal of Immunology 146, 2795-2804.
36. Roop, C., Hutchinson, L. & Johnson, D. C. (1993). A mutant herpes simplex virus type 1 unable to express glycoprotein L cannot enter cells, and its particles lack glycoprotein H. Journal of Virology 67, 2285-2297.
37. Simpson, J. A., Chow, J. C., Baker, J., Avdalovic, N., Yuan, S., Au, D., Co, M. S., Vasquez, M., Britt, W. J. & Coelingh, K. L. (1993). Neutralizing monoclonal antibodies that distinguish three antigenic sites on human cytomegalovirus glycoprotein H have conformationally distinct binding sites. Journal of Virology 67, 489-496.
38. Spaete, R. R., Perot, K., Scott, P. I., Nelson, J. A., Stinski, M. F. & Pachl, C. (1993). Coexpression of truncated cytomegalovirus gH with the UL115 gene product or the truncated human fibroblast growth factor receptor results in transport of gH to the cell surface. Virology 193, 853-861.
39. Spear, P. G. (1993). Membrane fusion induced by herpes simplex virus. In Viral Fusion Mechanisms, pp. 201-232. Edited by J. Bentz. Boca Raton: CRC Press.
40. Steel, H. M., Booth, J. C., Tryhorn, Y. S. & Stern, H. (1988). A simple immunoalkaline phosphatase method for the rapid diagnosis of cytomegalovirus (CMV) infection. Serodiagnosis and Immunotherapy in Infectious Disease 2, 193-200.
41. Taylor-Wiedeman, J., Sissons, J. G. P., Borysiewicz, L. K. & Sinclair, J. H. (1991). Monocytes are a major site of persistence of human cytomegalovirus in peripheral blood mononuclear cells. Journal of General Virology 72, 2059-2064.
42. Tevithia, M. J. & Spector, D. J. (1984). Complementation of an adenovirus 5 immediate early mutant by cytomegalovirus. Virology 137, 428-431.
43. Tevithia, M. J., Spector, D. J., Leisure, K. M. & Stinski, M. F. (1987). Participation of two human cytomegalovirus immediate early gene regions in transcriptional activation of adenovirus promoters. Virology 161, 276-285.
44. Tugizov, S., Navarro, D., Paz, P., Wang, Y., Qadri, I. & Pereira, L. (1994). Function of human cytomegalovirus glycoprotein B: syncytium formation in cells constitutively expressing gB is blocked by virus neutralizing antibodies. Virology 201, 263-276.
45. van Drunen Littel-van den Hurk, S., Khattar, S., Tikoo, S. K., Babiuk, L. A., Baranowski, E., Plainchamp, D. & Thiry, E. (1996). Glycoprotein H (gII/gp108) and glycoprotein L form a functional complex which plays a role in penetration, but not in attachment, of bovine herpesvirus 1. Journal of General Virology 77, 1515-1520.
46. Vinogradskaya, G. R., Goryshin, I. Y., Berlin, Y. A. & Lanzov, V. A. (1995). Optimization of PCR-based diagnostics for human cytomegalovirus. Journal of Virological Methods 53, 103-112.
47. Walev, I., Wollert, K. C., Weisem, K. & Falke, D. (1991). Characterisation of fusion from without induced by herpes simplex virus. Archives of Virology 117, 29-44.
48. Wigler, M., Silverstein, S., Lee, L. S., Pellicer, A, Cheng, Y.-C. & Axel, R. (1977). Transfer of purified herpesvirus thymidine kinase gene to cultured mouse cells. Cell 11, 223-232.
49. Wilkinson, G. W. & Akrigg, A. (1992). Constitutive and enhanced expression from the CMV major IE promoter in a defective adenovirus vector. Nucleic Acids Research 20, 2233-2239.
50. Wilson, D. W., Davis-Poynter, N. & Minson, A. C. (1994). Mutations in the cytoplasmic tail of herpes simplex virus glycoprotein H suppress cell fusion by a syncytial strain. Journal of Virology 68, 6985-6993.