Glycoprotein gH of pseudorabies virus is essential for penetration and propagation in cell culture and in the nervous system of mice

Journal of General Virology

Volumn 77, Issue 9, 1996, Pages 2277-2285

  Babic, Nathalie ^a   Klupp, Barbara G ^b   Makoschey, Birgit ^a   Karger, Axel ^b   Flamand, Anne ^a   Mettenleiter, Thomas C ^b  

^a CNRS   (France)

^b FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MACROGOL; VIRUS GLYCOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; FEMALE; GENETIC COMPLEMENTATION; MEMBRANE FUSION; MOUSE; NERVOUS SYSTEM; NONHUMAN; PRIORITY JOURNAL; PSEUDORABIES HERPETOVIRUS; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT INFECTION; SYMPATHETIC NERVE; TRIGEMINAL NERVE; VIRUS CELL INTERACTION; VIRUS INFECTION; VIRUS INFECTIVITY; VIRUS MUTANT; VIRUS REPLICATION;

ANIMALIA; HERPETOVIRUS; SUID HERPESVIRUS 1;

EID: 0029813074     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-77-9-2277     Document Type: Article

References (34)

1. Babic, N., Mettenleiter, T. C., Flamand, A. & Ugolini, G. (1993). Role of essential glycoproteins gII and gp50 in transneuronal transfer of pseudorabies virus from the hypoglossal nerves of mice. Journal of Virology 67, 4421-4426.
2. Babic, N., Mettenleiter, T. C., Ugolini, G., Flamand, A. & Coulon, P. (1994). Propagation of pseudorabies virus in the nervous system of the mouse after intranasal inoculation. Virology 204, 616-625.
3. Babic, N., Klupp, B., Brack, A., Mettenleiter, T. C., Ugolini, G. & Flamand, A. (1996). Deletion of glycoprotein gE reduces the propagation of pseudorabies virus in the nervous system of mice after intranasal inoculation. Virology 218, in press.
4. Balan, P., Davis-Poynter, N., Bell, S., Atkinson, S., Brown, H. & Minson, T. (1994). An analysis of the in vitro and in vivo phenotypes of mutants of herpes simplex virus type 1 lacking glycoproteins gG, gE, gI or the putative gJ. Journal of General Virology 75, 1245-1258.
5. Cai, W., Gu, B. & Person, S. (1988). Role of glycoprotein B of herpes simplex virus in viral entry and cell fusion. Journal of Virology 62, 2596-2604.
6. Card, J. P., Whealy, M. E., Robbins, A. K. & Enquist, L. W. (1992). Pseudorabies virus envelope glycoprotein gI influences both neurotropism and virulence during infection of the rat visual system. Journal of Neuroscience 66, 3032-3041.
7. Coulon, P., Derbin, C., Kucera, P., Lafay, F., Prehaud, C. & Flamand, A. (1989). Invasion of the peripheral nervous systems of adult mice by the CVS strain of rabies virus and its avirulent derivative AvO1. Journal of Virology 63, 3550-3554.
8. Dingwell, K. S., Doering, L. C. & Johnson D. C. (1995). Glycoproteins gE and gI facilitate neuron-to-neuron spread of herpes simplex virus. Journal of Virology 69, 7087-7098.
9. Farrell, H., McLean, C., Harley, C., Efstathiou, S. & Minson, A. C. (1994). Vaccine potential of a herpes simplex virus type 1 mutant with an essential glycoprotein deleted. Journal of Virology 68, 927-932.
10. Forrester, A., Farrell, H., Wilkinson, G., Kaye, J., Davis-Poynter, N. & Minson, A. C. (1992). Construction and properties of a mutant of herpes simplex virus type 1 with glycoprotein H coding sequences deleted. Journal of Virology 66, 341-348.
11. Graham, F. L. & van der Eb, A. J. (1973). A new technique for the assay of infectivity of human adenovirus. Virology 52, 456-467.
12. Heffner, S., Kovács, F., Klupp, B. & Mettenleiter, T. C. (1993). Glycoprotein gp50-negative pseudorabies virus: a novel approach toward a nonspreading live herpesvirus vaccine. Journal of Virology 67, 1529-1537.
13. Kaplan, A. & Vatter, A. (1959). A comparison of herpes simplex and pseudorabies viruses. Virology 7, 394-407.
14. Karger, A. & Mettenleiter, T. C. (1993). Glycoproteins gIII and gp50 play dominant roles in the biphasic attachment of pseudorabies virus. Virology 194, 654-664.
15. Klupp, B., Visser, N. & Mettenleiter, T. C. (1992). Identification and characterization of pseudorabies virus glycoprotein H. Journal of Virology 66, 3048-3055.
16. Klupp, B., Baumeister, J., Karger, A., Visser, N. & Mettenleiter, T. C. (1994). Identification and characterization of a novel structural glycoprotein in pseudorabies virus, gL. Journal of Virology 68, 3868-3878.
17. Kritas, S. K., Pensaert, M. B. & Mettenleiter, T. C. (1994). Role of envelope glycoproteins gI, gp63 and III in the invasion and spread of Aujeszky's disease virus in the olfactory nervous system pathway of the pig. Journal of General Virology 75, 2319-2327.
18. Lafay, F., Coulon, P., Astic, L., Saucier, D., Riche, D., Holley, A. & Flamand, A. (1991). Spread of the CVS strain of rabies virus and of the avirulent mutant AvO1 along the olfactory pathways of the mouse after intranasal inoculation. Virology 183, 320-330.
19. Ligas, M. & Johnson, D. (1988). A herpes simplex virus mutant in which glycoprotein D sequences are replaced by β-galactosidase sequences binds to but is unable to penetrate into cells. Journal of Virology 62, 1486-1494.
20. Mettenleiter, T. C. (1994). Pseudorabies (Aujeszky's disease) virus: state of the art. Acta Veterinaria Hungarica 42, 153-177.
21. Mettenleiter, T. C. & Rauh, I. (1990). A glycoprotein gX-β-galactosidase fusion gene as insertional marker for rapid identification of pseudorabies mutants. Journal of Virological Methods 30, 55-66.
22. Mettenleiter, T. C., Zsak, L., Zuckermann, F., Sugg, N., Kern, H. & Ben-Porat, T. (1990). Interaction of glycoprotein gill with a cellular heparinlike substance mediates adsorption of pseudorabies virus. Journal of Virology 64, 278-286.
23. Mulder, W. A. M., Jacobs, L., Priem, J., Kok, G. L., Wagenaar, F., Kimman, T. G. & Pol, J. M. A. (1994). Glycoprotein E-negative pseudorabies virus has a reduced capability to infect second and third order neurons of the olfactory and trigeminal routes in the porcine central nervous system. Journal of General Virology 75, 3095-3106.
24. Peeters, B., Dewind, N., Hooisma, M., Wagenaar, F., Gielkens, A. & Moormann, R. (1992a). Pseudorabies virus envelope glycoproteins gp50 and gII are essential for virus penetration but only gII is involved in membrane fusion. Journal of Virology 66, 894-905.
25. Peeters, B., Dewind, N., Broer, R., Gielkens, A. & Moormann, R. (1992b). Glycoprotein H of pseudorabies virus is essential for entry and cell-to-cell spread of the virus. Journal of Virology 66, 3888-3892.
26. Peeters, B., Pol, J., Gielkens, A. & Moormann, R. (1993). Envelope glycoprotein gp50 of pseudorabies virus is essential for virus entry but is not required for viral spread in mice. Journal of Virology 67, 170-177.
27. Rauh, I. & Mettenleiter, T. C. (1991). Pseudorabies virus glycoproteins gII and gp50 are essential for virus penetration. Journal of Virology 65, 5348-5356.
28. Rauh, I., Weiland, F., Fehler, F., Keil, G. & Mettenleiter, T. C. (1991). Pseudorabies virus mutants lacking the essential glycoprotein gII can be complemented by glycoprotein gI of bovine herpesvirus 1. Journal of Virology 65, 621-631.
29. Sarmiento, M., Haffey, M. & Spear, P. G. (1979). Membrane proteins specified by herpes simplex viruses. III. Role of glycoprotein VP7(B2) in virion infectivity. Journal of Virology 29, 1149-1158.
30. Sawitzky, D., Hampl, H. & Habermehl, K. O. (1990). Comparison of heparin-sensitive attachment of pseudorabies virus (PrV) and herpes simplex virus type 1 and identification of heparin-binding PrV glycoproteins. Journal of General Virology 71, 1221-1225.
31. Southern, P. J. & Berg, P. (1982). Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. Journal of Molecular and Applied Genetics 1, 327-341.
32. Spear, P. G. (1993). Entry of alphaherpesviruses into cells. Seminars in Virology 4, 167-180.
33. Standish, A., Enquist, L. W. & Schwaber, J. S. (1994). Vagal cardiac ventricular innervation and its central medullary origin demonstrated by viral tracing. Science 263, 232-234.
34. Strack, A. M. & Loewy, A. D. (1990). Pseudorabies virus: a highly specific transneuronal cell body marker in the sympathetic nervous system. Journal of Neurosciences 10, 2139-2147.