1,25-dihydroxy vitamin D3 and tri-iodothyronine stimulate the expression of a protein immunologically related to osteocalcin

Journal of Histochemistry and Cytochemistry

Volumn 46, Issue 4, 1998, Pages 477-486

  Luegmayr, Eva ^a   Varga, Franz ^a   Glantschnig, Helmut ^a   Fratzl Zelman, Nadja ^a   Rumpler, Monika ^a   Ellinger, Adolf ^a   Klaushofer, Klaus ^a  

^a HANUSCH HOSPITAL   (Austria)

Author keywords

1,25 dihydroxy vitamin D3; Green fluorescent protein; Immunohistochemistry; MC3T3 E1 cells; Osteocalcin; Tri iodothyronine

Indexed keywords

CALCITRIOL; CERAMIDE; GREEN FLUORESCENT PROTEIN; LIOTHYRONINE; MESSENGER RNA; OSTEOCALCIN;

ANIMAL CELL; ARTICLE; BREAST CARCINOMA; CARCINOMA CELL; CELL STRAIN 3T3; CONTROLLED STUDY; GOLGI STAIN; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALIA;

EID: 0031897642     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215549804600407     Document Type: Article

References (41)

1. Barille S, Pellat-Deceunynck C, Bataille R, Amiot M (1996) Ectopic secretion of osteocalcin, the major non-collagenous bone protein, by the myeloma cell line NCI-H929. J Bone Miner Res 11:466-471
2. Bos MP, Van der Meer JM, Feyen HJ, Herrmann-Erlee MP (1996) Expression of the parathyroid hormone receptor and correlation with other osteoblastic parameters in fetal rat osteoblasts. Calcif Tissue Int 58:95-100
3. Bradbeer JN, Virdi AS, Serre CM, Beresford JN, Delmas PD, Reeve J, Triffitt JT (1994) A number of osteocalcin antisera recognize epitopes on proteins other than osteocalcin in cultured skin fibroblasts: implications for the identification of cells of the osteoblastic lineage in vitro. J Bone Miner Res 9:1221-1228
4. 3 on collagen type I, osteopontin, and osteocalcin gene expression in chicken osteoblasts. J Cell Biochem 57:440-451
5. Celeste AJ, Rosen V, Buecker JL, Kriz R, Wang EA, Wozney JM (1986) Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones. EMBO J 5:1885-1890
6. Choi JY, Lee BH, Song KB, Park RW, Kim IS, Sohn KY, Jo JS, Ryoo HM (1996) Expression pattern of bone-related proteins during osteoblastic differentiation in MC3T3-E1 cells. J Cell Biochem 61:609-918
7. Ducy P, Desbois C, Boyce B, Pinerot G, Story B, Dunstan C, Smith E, Bonadio J, Goldstein S, Gundberg C, Bradley A, Karsenty G (1996) Increased bone formation in osteocalcin-deficient mice. Nature 382:448-452
8. Evans RM (1988) The steroid and thyroid hormone receptor superfamily. Science 240:889-895
9. Fleet JC, Hock JM (1994) Identification of osteocalcin mRNA in nonosteoid tissue of rats and humans by reverse transcription-polymerase chain reaction. J Bone Miner Res 9:1565-1573
10. Fratzl-Zelman N, Hörandner H, Luegmayr E, Varga F, Ellinger A, Erlee MPM, Klaushofer K (1997) Effects of triiodothyronine on the morphology of cells and matrix, the localization of alkaline phosphatase, and the frequency of apoptosis in long-term cultures of MC3T3-E1 cells. Bone 20:225-236
11. Gerdes HH, Kaether C (1996) Green fluorescent protein: applications in cell biology. FEBS Lett 389:44-47
12. 3) and retinoic acid induce the synthesis of insulin-like growth factor binding protein 4 in mouse osteoblastic cells. Endocrinology 137:281-286
13. Hauschka PV, Lian JB, Gallop PM (1975) Direct identification of the calcium-binding amino acid gamma-carboxyglutamic in mineralized tissue. Proc Natl Acad Sci USA 72:3925-3929
14. Haussler MR (1986) Vitamin D receptors: nature and function. Annu Rev Nutr 6:527-562
15. Kaether C, Gerdes HH (1995) Visualization of protein transport along the secretory pathway using green fluorescent protein. FEBS Lett 369:267-271
16. 3 on the proliferation of osteoblastic MC3T3-E1 cells by modulating the release of local regulators from monocytes. Biochem Biophys Res Commun 190:529-535
17. Kasono K, Sato S, Han D, Fujii Y, Tsushima T, Shizume K (1988) Stimulation of alkaline phospatase activity by thyroid hormone in mouse osteoblast-like cells (MC3T3-E1): a possible mechanism of hyperalkaline phosphatasia in hyperthyroidism. Bone Miner 4:355-363
18. Klaushofer K, Varga F, Glantschnig H, Fratzl-Zelman N, Czerwenka E, Leis HJ, Koller K, Peterlik M (1995) The regulatory role of thyroid hormones in bone cell growth and differentiation. J Nutr 125:1996S-2003S
19. 3 on osteoblastic MC3T3-E1 cells. Endocrinology 118:940-947
20. 4. Nature 227:680-685
21. 3 stimulation of a high molecular weight protein immunologically related to osteocalcin. J Bone Miner Res 1:S262
22. Lian JB, Shalhoub V, Aslam F, Frenkel B, Green J, Hamrah M, Stein GS, Stein JL (1997) Species-specific glucocorticoid and 1,25-dihydroxyvitamin D responsiveness in mouse MC3T3-E1 osteoblasts: dexamethasone inhibits osteoblast differentiation and vitamin D down-regulates osteocalcin gene expression. Endocrinology 138: 2117-2127
23. Lian JB, Stewart C, Puchacz E, Mackowiak S, Shaloub V, Collart D, Zambetti G, Stein G (1989) Structure of the rat osteocalcin gene and regulation of vitamin D-dependent expression. Proc Natl Acad Sci USA 686:1143-1147
24. Luegmayr E, Varga F, Frank T, Roschger P, Klaushofer K (1996) Effects of triiodothyronine on morphology, growth behaviour, and the actin cytoskeleton in mouse osteoblastic cells (MC3T3-E1). Bone 18:591-599
25. 3 on its receptor mRNA levels and osteocalcin synthesis in human osteosarcoma cells. Biochim Biophys Acta 1048:30-37
26. Malaval L, Modrowski D, Gupta AK, Aubin JE (1994) Cellular expression of bone-related proteins during in vitro osteogenesis in rat bone marrow stromal cell cultures. J Cell Physiol 158:555-572
27. Ohishi K, Ishida H, Nagata T, Yamauchi N, Tsurumi C, Nishikawa S, Wakano Y (1994) Thyroid hormone suppresses the differentiation of osteoprogenitor cells to osteoblasts, but enhances functional activities of mature osteoblasts in cultured rat calvaria cells. J Cell Physiol 161:544-552
28. Pagano RE, Sepanski MA, Martin OC (1989) Molecular trapping of a fluorescent ceramide analogue at the Golgi apparatus of fixed cells: interaction with endogenous lipids provides a trans-Golgi marker for both light and electron microscopy. J Cell Biol 109:2067-2079
29. 3-induced osteocalcin synthesis in human osteosarcoma cells by other steroidal hormones. Mol Cell Endocrinol 7:149-159
30. Pockwinse SM, Stein JL, Lian JB, Stein GS (1995) Developmental stage-specific cellular responses to vitamin D and glucocorticoids during differentiation of the osteoblast phenotype: interrelationship of morphology and gene expression by in situ hybridization. Exp Cell Res 216:244-260
31. Prasher DC, Eckenrode VK, Ward WW, Prendergast FG, Cormier MJ (1992) Primary structure of the Aequorea victoria green-fluorescent protein. Gene 111:229-233
32. Price PA, Otuska D, Poser JW, Kristaposis J, Raman N (1976) Characterization of a gamma-carboxyglutamic containing protein from bone. Proc Natl Acad Sci USA 73:1447-1451
33. 3 on alkaline phosphatase and bone Gla-protein of rat osteoblastic cells. Endocrinology 118:1340-1346
34. Stein GS, Lian JB, Owen TA (1990) Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation. FASEB J 4:3111-3123
35. 3 inhibits synthesis and enhances degradation of proteoglycans in osteoblastic cells. J Biol Chem 264:18407-18413
36. Thiede MA, Smock SL, Petersen DN, Grasser WA, Thompson DD, Nishimoto SK (1994) Presence of messenger ribonucleic acid encoding osteocalcin, a marker of bone turnover, in bone marrow megakaryocytes and peripheral blood platelets. Endocrinology 135:929-937
37. 3 and parathyroid hormone. Biochim Biophys Acta 1312:54-62
38. Varga F, Rumpler M, Klaushofer K (1994) Thyroid hormones increase insulin-like growth factor mRNA levels in the clonal osteoblastic cell line MC3T3-E1. FEBS Lett 345:67-70
39. Varga F, Rumpler M, Luegmayr E, Fratzl-Zelman N, Glantschnig H, Klaushofer K (1997) Triiodothyronine a regulator of osteoblastic differentiation: depression of histone-H4, attenuation of c-fos/c-jun and induction of osteocalcin expression. Calcif Tiss Int 61:404-411
40. Weinreb M, Shinar D, Rodan GA (1990) Different pattern of alkaline phosphatase, osteopontin and osteocalcin expression in developing rat bone visualized by in situ hybridization. J Bone Miner Res 5:831-842
41. 3 inhibits osteocalcin expression in mouse through an indirect mechanism. J Biol Chem 272:110-116