Doublex sequencing in molecular diagnosis of hereditary diseases

BioTechniques

Volumn 24, Issue 5, 1998, Pages 838-841

  Plaschke, Jens ^a,c   Voss, H ^b   Hahn, M ^a   Ansorge, W ^b   Schackert, H K ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ARTICLE; CONTROLLED STUDY; COST CONTROL; DIAGNOSTIC ACCURACY; DNA SEQUENCE; GENE MUTATION; GENETIC DISORDER; HUMAN; POLYMERASE CHAIN REACTION;

EID: 0031895019     PISSN: 07366205     EISSN: None     Source Type: Journal    
DOI: 10.2144/98245dt06     Document Type: Article

References (8)

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3. Kilger, C. and S. Pääbo. 1997. Direct exponential amplification and sequencing (DEXAS) of genomic DNA. Biol. Chem. 378:99-105.
4. Kolodner, R.D., N.R. Hall, J. Lipford, M.F. Kane, P.T. Morrison, P.J. Finan, J. Burn, P. Chapman et al. 1995. Structure of the human MLH1 locus and analysis of a large hereditary nonpolyposis colorectal carcinoma kindred for mlh1 mutations. Cancer Res. 55:242-248.
5. Kolodner, R.D., N.R. Hall, J. Lipford, M.F. Kane, M.R.S. Rao, P. Morrison, L. Wirth, P.J. Finan et al. 1994. Structure of the human MSH2 locus and analysis of two Muir-Torre kindreds for msh2 mutations. Genomics 24:516-526.
6. Simard, J., P. Tonin, F. Durocher, K. Morgan, J. Rommens, S. Gingras, C. Samson, J.-F. Leblanc et al. 1994. Common origins of BRCA1 mutations in Canadian breast and ovarian cancer families. Nature Genet. 8:392-398.
7. Tabor, S. and C.C. Richardson. 1995. A single residue in DNA polymerases of E. coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides. Proc. Natl. Acad. Sci. USA 92:6339-6343.
8. Wiemann, S., J. Stegemann, D. Grothues, A. Bosch, X. Esttivill, C. Schwager, J. Zimmermann, H. Voss and W. Ansorge. 1995. Simultaneous on-line DNA sequencing on both strands with flourescent dyes. Anal. Biochem. 224:117-121.