Genetic basis of response to 50 generations of selection on body weight in inbred mice

Genetics

Volumn 148, Issue 4, 1998, Pages 1931-1939

  Keightley, Peter D ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; EVOLUTION; FEMALE; GENE MUTATION; GENETIC SELECTION; GENETIC VARIABILITY; HERITABILITY; INBRED STRAIN; LITTER SIZE; MALE; MAXIMUM LIKELIHOOD METHOD; MOUSE; NONHUMAN; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL;

AGE FACTORS; ANIMALS; BODY WEIGHT; FEMALE; INBREEDING; MALE; MICE; MICE, INBRED C3H; MUTATION; SELECTION (GENETICS);

ANIMALIA; RODENTIA;

EID: 0031891298     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. BRADFORD, G. E., and T. R. FAMULA, 1984 Evidence for a major gene for rapid postweaning growth in mice. Genet. Res. 44: 293-308.
2. CABALLERO, A., and P. D. KEIGHTLEY, 1998 Inferences on genome-wide deleterious mutation rates in inbred populations of Drosophila and mice. Genetica (in press).
3. CABALLERO, A., M. A. TORO and C. LOPEZ-FANJUL, 1991 The response to artificial selection from new mutations in Drosophila melanogaster. Genetics 127: 89-102.
4. CABALLERO, A., P. D. KEIGHTLEY and W. G. HILL, 1990 Accumulation of mutations affecting body weight in inbred mouse lines. Genet. Res. 65: 145-149.
5. CLAYTON, G., and A. ROBERTSON, 1955 Mutation and quantitative variation. Am. Nat. 89: 151-158.
6. COCKERHAM, C. C., 1986 Modifications in estimating the number of genes for a quantitative character. Genetics 114: 659-664.
7. DIETRICH, W., H. KATZ, S. E. LINCOLN, H. SHIN, J. FRIEDMAN et al., 1992 A genetic map of the mouse suitable for typing intraspecific crosses. Genetics 131: 423-447.
8. ELSTON, R. C., 1979 Major locus analysis for quantitative traits. Am. J. Hum. Genet. 31: 655-661.
9. FALCONER, D. S., and T. F. C. MACKAY, 1996 Introduction to Quantitative Genetics, Ed. 4, Longman Scientific and Technical, Harlow, Essex, UK.
10. FESTING, M., 1973 A multivariate analysis of subline divergence in the shape of the mandible in C57BL/Gr mice. Genet. Res. 21: 121-132.
11. FESTING, M. F. W., 1989 Inbred strains of mice, pp. 636-648 in Genetic Variants and Strains of the Laboratory Mouse, edited by M. F. LYON and A. G. SEARLE. Oxford University Press, New York.
12. FRY, J. D., K. A. DERONDE and T. F. C. MACKAY, 1995 Polygenic mutation in Drosophila melanogaster: genetic analysis of selection lines. Genetics 139: 1293-1307.
13. GENSTAT 5 COMMITTEE, 1993 Genstat 5 Release 3 Reference Manual. Clarendon Press, Oxford.
14. Go, R. C. P., R. C. ELSTON and E. B. KAPLAN, 1978 Efficiency and robustness of pedigree segregation analysis. Am. J. Hum. Genet. 30: 28-37.
15. HALEY, C. S., G. J. LEE, R. WEBB and S. A. KNOTT, 1993 Evidence on the genetic control of LH release in response to GnRH from crosses between selected lines of sheep. Livest. Prod. Sci. 37: 153-167.
16. HEATH, S. C., G. BULFIELD, R. THOMPSON and P. D. KEIGHTLEY, 1995 Rates of change of genetic parameters of body weight in selected mouse lines. Genet. Res. 66: 19-25.
17. HILL, W. G., 1982a Rates of change in quantitative traits from fixation of new mutations. Proc. Nat. Acad. Sci. USA 79: 142-145.
18. HILL, W. G., 1982b Predictions of response to artificial selection from new mutations. Genet. Res. 40: 255-278.
19. HOULE, D., B. MORIKAWA and M. LYNCH, 1996 Comparing mutational variabilities. Genetics 143: 1467-1483.
20. JUGA, J., and R. THOMPSON, 1989 Estimation of variance components in populations selected over multiple generations. Acta Agric. Scand. 39: 78-89.
21. KEIGHTLEY, P. D., and S. HAWKINS, 1991 Rimy: a new mutation affecting coat colour and body size. Mouse Genome 89: 410.
22. KEIGHTLEY, P. D., and W. G. HILL, 1992 Quantitative genetic variation in body size of mice from new mutations. Genetics 131: 693-700.
23. KEIGHTLEY, P. D., and G. BULFIELD, 1993 Detection of quantitative trait loci from frequency changes at marker loci under selection. Genet. Res. 62: 195-203.
24. KIMURA, M., and J. F. CROW, 1963 On the maximum avoidance of inbreeding. Genet. Res. 4: 399-415.
25. KIRKPATRICK, M., and R. LANDE, 1989 The evolution of maternal characters. Evolution 43: 485-503.
26. LANDE, R., 1981 The minimum number of genes contributing to quantitative variation between and within populations. Genetics 99: 541-553.
27. LOPEZ, M. A., and C. LOPEZ-FANJUL, 1993a Spontaneous mutation for a quantitative trait in Drosophila melanogaster. I. Response to artificial selection. Genet. Res. 61: 107-116.
28. LOPEZ, M. A., and C. LOPEZ-FANJUL, 1993b Spontaneous mutation for a quantitative trait in Drosophila melanogaster. II. Distribution of mutant effects on the trait and fitness. Genet. Res. 61: 117-126.
29. LYNCH, M., and W. G. HILL, 1986 Phenotypic evolution by neutral mutation. Evolution 40: 915-935.
30. LYON, M., and A. SEARLE, 1989 Genetic Variants and Strains of the Laboratory Mouse, Ed. 2, Oxford University Press, Oxford.
31. MACKAY, T. F. G., J. D. FRY, R. F. LYMAN and S. V. NUZHDIN, 1994 Polygenic mutation in Drosophila melanogaster: estimates from response to selection in inbred strains. Genetics 136: 937-951.
32. MERCHANTE, M., A. CABALLERO and C. LOPEZ-FANJUL, 1995 Response to selection from new mutation and effective size of partially inbred populations. II. Experiments with Drosophila melanogaster. Genet. Res. 66: 227-240.
33. MEYER, K., 1989 Restricted maximum likelihood to estimate variance components for animal models with several random effects using a derivative-free approach. Genet. Sel. Evol. 21: 317-340.
34. NELDER, J. A., and R. MEAD, 1965 A simplex method for function minimization. Comput. J. 7: 308-313.
35. NUZHDIN, S. V., J. D. FRY and T. F. C. MACKAY, 1995 Polygenic mutation in Drosophila melanogaster - the causal relationship of bristle number to fitness. Genetics 139: 861-872.
36. PRESS, W. H., S. A. TEUKOLSKY, W. T. VETTERLING and B. P. FLANNERY, 1992 Numerical Recipes in C, Ed. 2, Cambridge University Press, Cambridge.
37. ROBERTS, R. C., 1966 The limits to artiticial selection for body weight in the mouse. II. The genetic nature of the limits. Genet. Res. 8: 361-375.
38. SOKAL, R. R., and F. J. ROHLF, 1995 Biometry, Ed. 3, W. H. Freeman and Company, New York.
39. WRAY, N. R., 1990 Accounting for mutation effects in the additive genetic variance-covariance matrix and its inverse. Biometrics 46: 177-186.
40. ZENG, Z.-B., 1992 Correcting the bias of Wright's estimates of the number of genes affecting a quantitative character: a further improved method. Genetics 131: 987-1001.
41. ZENG, Z.-B., D. HOULE and C. C. COCKERHAM, 1990 How informative is Wright's estimator of the number of genes affecting a quantitative character? Genetics 126: 235-247.