Phase II-selective induction of hepatic drug-metabolizing enzymes by oltipraz [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione], 1,7-phenanthroline, and 2,2'-dipyridyl in rats is not accompanied by induction of intestinal enzymes

Drug Metabolism and Disposition

Volumn 26, Issue 2, 1998, Pages 91-97

  Vargas, Maricelly ^b   Lamb, John G ^b   Franklin, Michael R ^a  

^a UNIVERSITY OF UTAH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

1 NAPHTHOL; 2 HYDROXYBIPHENYL; 2 NAPHTHOL; 3 METHYLCHOLANTHRENE; 4 NITROPHENOL; BIPYRIDINE; BUTYLATED HYDROXYANISOLE; CYTOCHROME P450; ESTRONE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE DERIVATIVE; HYMECROMONE; INTESTINE ENZYME; MESSENGER RNA; MORPHINE; OLTIPRAZ; PHENANTHROLINE; PHENOBARBITAL; PHENOLPHTHALEIN; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ASSAY; ENZYME INDUCTION; ENZYME LOCALIZATION; ENZYME MECHANISM; LIVER METABOLISM; MALE; MESSENGER RNA SYNTHESIS; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT;

2,2'-DIPYRIDYL; ANIMALS; BUTYLATED HYDROXYANISOLE; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; INTESTINES; MALE; METABOLIC DETOXICATION, DRUG; MICROSOMES, LIVER; MOLECULAR STRUCTURE; NAD(P)H DEHYDROGENASE (QUINONE); PHENANTHROLINES; PYRAZINES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

ANIMALIA;

EID: 0031890965     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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