Synthesis of novel oligodeoxynucleotide conjugates containing the anionophoric moiety of pamamycin

Nucleosides and Nucleotides

Volumn 17, Issue 1-3, 1998, Pages 309-316

  Uhlmann, E ^a   Hornung, L ^a   Will, D W ^a   Grafe U ^b  

^a SANOFI   (France)

^b HANS KNÖLL INSTITUTE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; COMPLEMENTARY DNA; OLIGODEOXYNUCLEOTIDE DERIVATIVE; PAMAMYCIN; PHOSPHOROTHIOIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG CONJUGATION; DRUG DESIGN; DRUG PENETRATION; DRUG SYNTHESIS; HYDROLYSIS; LIPOPHILICITY; STREPTOMYCES;

STREPTOMYCES; STREPTOMYCES AURANTIACUS;

EID: 0031887058     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/07328319808005179     Document Type: Article

References (15)

1. Uhlmann, E., Peyman, A., Chem. Rev. 1990, 90, 543-84.
2. Thuong, N. T., Hélène, C., Angew. Chem. Int. Ed. Engl. 1993, 32, 666-690.
3. Wagner, R. W. et al., Science 1993, 260, 1510-1513.
4. Crooke, S. T., Lebleu, B. (ed.) in Antisense Research and Applications, 1993 (CRC Press, Boca Raton).
5. Stein, C. A., Chemistry & Biology 1996, 3, 319-323.
6. Yeoman, L. C., Danels, Y. J., Lynch, M. J., Antisense Res. Dev. 1992, 2, 51-59.
7. Uhlmann, E., Peyman, A. Will, D. W. in Antisense: Chemical Modifications in Encylopedia of Cancer ; Bertino, J. (ed.), 1997, Vol. 1, pp. 64-81, (Academic Press, San Diego).
8. Letsinger, R.L., Zhang, G., Sun, D.K., Ikeuchi, T., Sarin, P.S., Proc. Natl. Acad. Sci. U. S. A. 1989, 86, 6553-6556.
9. Will, D.W., Brown, T., Tetrahedron Lett. 1992, 33, 2729-2732.
10. Gräfe, U., Stengel, C., Möllemann, U., Heinisch, L., Pharmazie 1994, 49, 343-346.
11. Natsume, M., Yasui, K., Kondo, S., Marumo, S., Tetrahedron Lett. 1991, 32, 3087-3090.
12. Gräfe, U., Uhlmann, E., unpublished results.
13. Peyman, A., Uhlmann, E., Biol. Chem. Hoppe-Seyler 1996, 377, 67-70.
14. Peyman, A., Helsberg, M., Kretzschmar, G., Mag, M., Grabley, S., Uhlmann, E., Biol. Chem. Hoppe-Seyler 1995, 376, 195-198.
15. Iyer, K.P., Egan, W., Regan, J.B., Beaucage, S.L., J. Am. Chem. Soc. 1990, 112, 1253-1254.