Mild hypothermia protects rat hippocampal CA1 neurons from irreversible membrane dysfunction induced by experimental ischemia

Neuroscience Research

Volumn 30, Issue 1, 1998, Pages 1-6

  Onitsuka, Meiko ^a   Mihara, Satoshi ^a   Inokuchi, Hiroe ^a   Shigemori, Minoru ^a   Higashi, Hideho ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Hippocampal CA1 neuron; Hypothermia; Intracellular recording; Neuroprotection; Oxygen and glucose deprivation; Temperature coefficient

Indexed keywords

GLUCOSE; OXYGEN;

ARTICLE; BRAIN ISCHEMIA; BRAIN SLICE; CELL MEMBRANE DEPOLARIZATION; HIPPOCAMPUS; HYPERPOLARIZATION; HYPOTHERMIA; MEMBRANE STEADY POTENTIAL; NERVE CELL MEMBRANE; NERVE CELL MEMBRANE POTENTIAL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; TEMPERATURE;

ANIMALS; ANOXIA; CELL MEMBRANE; GLUCOSE; HIPPOCAMPUS; HYPOTHERMIA, INDUCED; ISCHEMIC ATTACK, TRANSIENT; MALE; MEMBRANE POTENTIALS; PYRAMIDAL CELLS; RATS; RATS, WISTAR; REACTION TIME;

EID: 0031886495     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(97)00110-7     Document Type: Article

References (40)

1. Bramlett H.M., Green E.J., Dietrich W.D., Busto R., Globus M.Y.-T., Ginsberg M.D. Posttraumatic brain hypothermia provides protection from sensorimotor and cognitive behavioral deficits. J. Neurotrauma. 12:1995;289-298.
2. Busto R., Dietrich W.D., Globus M.Y.-T., Valdés I., Scheinberg P., Ginsberg M.D. Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury. J. Cereb. Blood Flow Metab. 7:1987;729-738.
3. Busto R., Dietrich W.D., Globus M.Y.-T., Ginsberg M.D. Postischemic moderate hypothermia inhibits CA1 hippocampal ischemic neuronal injury. Neurosci. Lett. 101:1989;299-304.
4. Choi D.W. Calcium: still center-stage in hypoxic-ischemic neuronal death. Trends Neurosci. 18:1995;58-60.
5. Choi D.W., Rothman S.M. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu. Rev. Neurosci. 13:1990;171-182.
6. Clifton G.L., Taft W.C., Blair R.E., Choi S.C., Delorenzo R.J. Conditions for pharmacologic evaluation in the gerbil model of forebrain ischemia. Stroke. 20:1989;1545-1552.
7. Clifton G.L., Jiang J.Y., Lyeth B.G., Jenkins L.W., Hamm R.J., Hayes R.L. Marked protection by moderate hypothermia after experimental traumatic brain injury. J. Cereb. Blood Flow Metab. 11:1991;114-121.
8. Clifton G.L., Allen S., Barrodale P., Plenger P., Berry J., Koch S., Fletcher J., Hayes R.L., Choi S.C. A phase II study of moderate hypothermia in severe brain injury. J. Neurotrauma. 10:1993;263-271.
9. 2+-activated nonspecific cation current in CA1 hippocampal neurons. J. Neurophysiol. 72:1994;1561-1569.
10. Dawson T.M., Snyder S.H. Gases as biological messengers: Nitric oxide and carbon monoxide in the brain. J. Neurosci. 14:1994;5147-5159.
11. Fujimura N., Tanaka E., Yamamoto S., Shigemori M., Higashi H. Contribution of ATP-sensitive potassium channels to hypoxic hyperpolarization in rat hippocampal CA1 neurons in vitro. J. Neurophysiol. 77:1997;378-385.
12. Fujiwara N., Higashi H., Shimoji K., Yoshimura M. Effects of hypoxia on rat hippocampal neurones in vitro. J. Physiol. 384:1987;131-151.
13. 2 in cat cerebral cortex. Am. J. Physiol. 219:1970;814-821.
14. Gao T.M., Xu Z.C. In vivo intracellular demonstration of an ischemia-induced postsynaptic potential from CA1 pyramidal neurons in rat hippocampus. Neuroscience. 75:1996;665-669.
15. Gross S.S., Wolin M.S. Nitric oxide: pathophysiological mechanisms. Annu. Rev. Physiol. 57:1995;737-769.
16. Hansen A.J. Effect of anoxia on ion distribution in the brain. Physiol. Rev. 65:1985;101-148.
17. Higashi H., Sugita S., Matsunari S., Nishi S. Calcium-dependent potentials with different sensitivities to calcium agonists and antagonists in guinea-pig hippocampal neurons. Neuroscience. 34:1990;35-47.
18. Hille, B., 1992. Ionic Channels of Excitable Membranes. Sinauer, Sunderland, MA.
19. Holtzman D.M., Sheldon R.A., Jaffe W., Cheng Y., Ferriero D.M. Nerve growth factor protects the neonatal brain against hypoxic-ischemic injury. Ann. Neurol. 39:1996;114-122.
20. Hori N., Carpenter D.O. Functional and morphological changes induced by transient in vivo ischemia. Exp. Neurol. 129:1994;279-289.
21. Kimura J.E., Reeves H. The effect of temperature on the asymmetrical charge movement in squid giant axons. J. Physiol. 289:1979;479-500.
22. Kirino T., Robinson H.P.C., Miwa A., Tamura A., Kawai N. Disturbance of membrane function preceding ischemic delayed neuronal death in the gerbil hippocampus. J. Cereb. Blood Flow Metab. 12:1992;408-417.
23. 2+ concentration of rat hippocampal slice during hypoxia. Neurosci. Res. Suppl. 9:1989;S33.
24. Leblond J., Krnjević K. Hypoxic changes in hippocampal neurons. J. Neurophysiol. 62:1989;1-14.
25. Marion D.W., Obrist W.D., Carlier P.M., Penrod L.E., Darby J.M. The use of moderate therapeutic hypothermia for patients with severe head injuries: a preliminary report. J. Neurosurg. 79:1993;354-362.
26. Martin R.L., Lloyd H.G.E., Cowan A.I. The early events of oxygen and glucose deprivation: setting the scene for neuronal death? Trends Neurosci. 17:1994;251-257.
27. Meldrum B., Garthwaite J. Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmacol. Sci. 11:1990;379-387.
28. Mellergard P. Changes in human intracerebral temperture in response to different methods of brain cooling. Neurosurgery. 31:1992;671-677.
29. Mitani A., Kataoka K. Critical levels of extracellular glutamate mediating gerbil hippocampal delayed neuronal death during hypothermia: brain microdialysis study. Neuroscience. 42:1991;661-670.
30. 2+ release. Trends Pharmacol. Sci. 16:1995;356-359.
31. Nicholls D., Attwell D. The release and uptake of excitatory amino acids. Trends Pharmacol. Sci. 11:1990;462-468.
32. Onitsuka M., Mihara S., Higashi H., Shigemori M. Role of nitric oxide (NO) and temperature in the experimental ischemia-induced membrane dysfunction of hippocampal neurons in vitro. J. Neurotrauma. 12:1995;395.
33. Resnick D.K., Marion D.W., Darby J.M. The effect of hypothermia on the incidence of delayed traumatic intracerebral hemorrhage. Neurosurgery. 34:1994;252-256.
34. Shiozaki T., Sugimoto H., Taneda M., Yoshida H., Iwai A., Yoshioka T., Sugimoto T. Effect of mild hypothermia on uncontrollable intracranial hypertension after severe head injury. J. Neurosurg. 79:1993;363-368.
35. Tanaka, E., Yamamoto, S., Kudo, Y., Mihara, S., Higashi, H., 1997. Mechanisms underlying the rapid depolarization produced by deprivation of oxygen and glucose in rat hippocampal CA1 neurons. J. Neurophysiol. 78, 891-902.
36. Thoenen H. The changing scene of neurotrophic factors. Trends Neurosci. 14:1991;165-170.
37. ATP channel mediation of anoxia-induced outward current in rat dorsal vagal neurones in vitro. J. Physiol. 487:1995;37-50.
38. Xu Z.C., Pulsinelli W.A. Response of CA1 pyramidal neurons in rat hippocampus to transient forebrain ischemia: an in vivo intracellular recording study. Neurosci. Lett. 171:1994;187-191.
39. Xu Z.C., Pulsinelli W.A. Electrophysiological changes of CA1 pyramidal neurons following transient forebrain ischemia: an in vivo intracellular recording and staining study. J. Neurophysiol. 76:1996;1689-1697.
40. Yamamoto, S., Tanaka, E., Shoji, Y., Kudo, Y., Inokuchi, H., Higashi, H., 1997. Factors that reverse the persistant depolarization produced by deprivatization of oxygen and glucosein rat hippocampal CA1 neurons in vitro. J. Neurophysiol. 78, 903-911.