Anti-collagenolytic mechanism of action of doxycycline treatment in rheumatoid arthritis

Rheumatology International

Volumn 17, Issue 5, 1998, Pages 175-180

  Nordstrom D ^a   Lindy, O ^b   Lauhio, A ^a   Sorsa, T ^b   Santavirta, S ^a   Konttinen, Y T ^a,b,c  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c ORTON Invalid Foundation   (Finland)

Author keywords

Collagenases; Doxycycline; Matrix metalloproteinases; Rheumatoid arthritis; Therapy

Indexed keywords

C REACTIVE PROTEIN; COLLAGENASE; DOXYCYCLINE; HEMOGLOBIN; MATRIX METALLOPROTEINASE; NEUTROPHIL COLLAGENASE; PROCOLLAGENASE; TETRACYCLINE DERIVATIVE;

ANTIMICROBIAL ACTIVITY; ARTICLE; CARTILAGE CELL; CLINICAL ARTICLE; CLINICAL TRIAL; COLLAGEN DEGRADATION; CONTROLLED STUDY; DENSITOMETRY; DISABILITY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; ERYTHROCYTE SEDIMENTATION RATE; FIBROBLAST; GLYCOSYLATION; HUMAN; IMMUNOBLOTTING; LASER; MENTAL DISEASE; MESENCHYME; PAIN ASSESSMENT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RATING SCALE; REACTIVE ARTHRITIS; RHEUMATOID ARTHRITIS; SALIVA ANALYSIS; SCORING SYSTEM; STATISTICAL ANALYSIS; TISSUE DEGENERATION; TREATMENT OUTCOME;

ANTI-BACTERIAL AGENTS; ARTHRITIS, RHEUMATOID; BLOOD SEDIMENTATION; BLOTTING, WESTERN; C-REACTIVE PROTEIN; COLLAGENASES; DOXYCYCLINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; HEMOGLOBINS; HUMANS; JOINTS; MATRIX METALLOPROTEINASE 8; PAIN MEASUREMENT; PSYCHIATRIC STATUS RATING SCALES; SALIVA; SEVERITY OF ILLNESS INDEX; SODIUM DODECYL SULFATE; TIME FACTORS;

EID: 0031886088     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002960050030     Document Type: Article

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