Litebamine N-homologues: Preparation and anti-acetylcholinesterase activity

Journal of Natural Products

Volumn 61, Issue 1, 1998, Pages 46-50

  Chiou, Chi Ming ^a   Kang, Jaw Jou ^a   Lee, Shoei Sheng ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; ALKALOID DERIVATIVE; PHENANTHRENE DERIVATIVE;

ALKYLATION; ARTICLE; DRUG ISOLATION; DRUG SYNTHESIS; ENZYME ACTIVITY; NONHUMAN; WOOD;

ANIMALS; CHOLINESTERASE INHIBITORS; ELECTRIC ORGAN; ELECTROPHORUS; ISOQUINOLINES; MAGNETIC RESONANCE SPECTROSCOPY; MANNICH BASES; PLANTS; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0031885191     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np970298f     Document Type: Article

References (18)

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13. For review of the phenanthrene alkaloids, see Guinaudeau, H; Lebœuf, M.; Cavé, A. J. Nat. Prod. 1975, 38, 275-338; 1979, 42, 325-360; 1983, 46, 761-835; 1988, 51, 389-474; 1994, 57, 1033-1135.
14. For review of the phenanthrene alkaloids, see Guinaudeau, H; Lebœuf, M.; Cavé, A. J. Nat. Prod. 1975, 38, 275-338; 1979, 42, 325-360; 1983, 46, 761-835; 1988, 51, 389-474; 1994, 57, 1033-1135.
15. For review of the phenanthrene alkaloids, see Guinaudeau, H; Lebœuf, M.; Cavé, A. J. Nat. Prod. 1975, 38, 275-338; 1979, 42, 325-360; 1983, 46, 761-835; 1988, 51, 389-474; 1994, 57, 1033-1135.
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18. Molecular modeling was performed on an Indy workstation (Silicon Graphic Inc.) using SYBYL software (version 6.03) (Tripos Associates Inc.) to obtain a conformation of minimum energy for litebamine and a zigzag extended conformation of minimum energy for acetylcholine, of which the distance between the corresponding O and N atoms was measured.