Antiplatelet effects of some aporphine and phenanthrene alkaloids in rabbits and man

Journal of Pharmacy and Pharmacology

Volumn 49, Issue 7, 1997, Pages 706-711

  Teng, Che Ming ^a   Hsueh, Cheung Mei ^a   Chang, Ya Ling ^a   Ko, Feng Nien ^a   Lee, Shoei Sheng ^a   Liu, Karin Chiung Sheue ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADRENALIN; ANTITHROMBOCYTIC AGENT; APORPHINE DERIVATIVE; ARACHIDONIC ACID; BOLDINE; COLLAGEN; CYCLIC AMP; INDOMETACIN; INOSITOL PHOSPHATE; PHENANTHRENE; THROMBIN; THROMBOCYTE ACTIVATING FACTOR; THROMBOXANE A2; THROMBOXANE B2;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; RABBIT; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE RICH PLASMA;

EID: 0030857029     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1997.tb06096.x     Document Type: Article

References (20)

1. Chen, C. C., Lin, C. F., Huang, Y. L., Ko, F. N., Teng, C. M. (1995a) Bioactive constituents from the flower buds and peduncles of Lindera megaphylla. J. Nat. Prod. 58: 1423-1425
2. Chen, I. S., Chen, J. J., Tsai, I. L., Chang, Y. L., Teng, C. M. (1995b) New p-quinonoid aporphine alkaloids and antiplatelet aggregation constituents of Hernandia sonora. Planta Medica 61: 537-539
3. Chen, K. S., Ko, F. N., Teng, C. M., Wu, Y. C. (1996a) Antiplatelet and vasorelaxing actions of some benzylisoquinoline and phenanthrene alkaloids. J. Nat. Prod. 59: 531-534
4. Chen, K. S., Wu, Y. C., Ko, F. N., Teng, C. M. (1996b) Antiplatelet and vasorelaxing action of some aporphinoids. Planta Medica 62: 133-136
5. DeLuca, M., McElory, W. D. (1978) Purification and properties of firefly luciferase. Methods Enzymol. 57: 3-15
6. Guh, J. H., Ko, F. N., Yu, S. M., Wu, Y. C., Teng, C. M. (1995) Pharmacological evaluation of N-methylactinodaphnine, a novel vascular α-adrenoceptor antagonist, isolated from Illigera luzonensis. Eur. J. Pharmacol. 279: 33-41
7. Hamberg, M., Svensson, J., Samuelsson, B. (1975) Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. Proc. Natl Acad. Sci. USA 72: 2994-2998
8. Huang, E. M., Detwiler, T. C. (1986a) Effect of lithium on platelet phosphoinositide metabolism. Biochem. J. 236: 895-901
9. Huang, E. M., Detwiler, T. C. (1986b) Stimulus-response coupling mechanisms. In: Phillips, D. R., Shuman, M. A. (eds) Biochemistry of Platelets. Academic Press, New York, pp 1-68
10. Karniguian, A., Legrand, Y. J., Caen, J. P. (1982) Prostaglandins: specific inhibition of platelet adhesion to collagen and relationship with cAMP level. Prostaglandins 23: 437-457
11. Ko, F. N., Yu, S. M., Su, M. J., Wu, T. S., Teng, C. M. (1993) Pharmacological activity of (-)-discretamine, a novel vascular α-adrenoceptor and 5-hydroxytryptamine receptor antagonist, isolated from Fissistigma glaucescens. Br. J. Pharmacol. 110: 882-888
12. Ko, F. N., Yeh, L. J., Liang, H. C., Kuo, S. C., Teng, C. M. (1996) Mechanism of action of p-chlorobiphenyl on the inhibition of platelet aggregation. J. Pharm. Pharmacol. 48: 395-400
13. Lee, S. S., Lin, Y. J., Wu, Y. C., Chen, C. H. (1992) A facile semisynthesis of litebamine, a novel phenanthrene alkaloid, from boldine via a biogenetical approach. Tetrahedron Lett. 33: 6309-6310
14. Lee, S. S., Tsai, F. Y., Chen, I. S., Liu, K. C. S. (1993) Additional alkaloids from Phoebe formosana. J. Chin. Chem. Soc. 40: 209-212
15. 1-adrenoceptors in rat kidney mediate increased inositol phospholipid hydrolysis. Br. J. Pharmacol. 91: 367-376
16. Nishizuka, Y. (1984) Turnover of inositol phospholipids and signal transduction. Science 225: 1365-1370
17. O'Brien, J. R. (1962) Platelet aggregation II. Some results from a new method of study. J. Clin. Pathol. 15: 452-455
18. Teng, C. M., Chen, W. Y., Ko, W. C., Ouyang, C. (1987) Antiplatelet effect of butylidenephthalide. Biochim. Biophys. Acta 924: 375-382
19. 1-adrenergic antagonist, isolated from Lindera megaphylla. Br. J. Pharmacol. 104: 651-656
20. Vane, J. R., Aanggard, E. E., Botting, R. M. (1990) Regulatory functions of the vascular endothelium. N. Engl. J. Med. 223: 27-36