Spontaneous apoptosis in ovarian cancer: An unfavorable prognostic factor

International Journal of Oncology

Volumn 12, Issue 2, 1998, Pages 351-354

  Mattern, J ^a   Stammler, G ^a   Koomagi R ^a   Wallwiener, D ^b   Kaufmann, M ^b   Volm, M ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Angiogenesis; Apoptosis; Cell proliferation; Ovarian carcinoma; Prognosis

Indexed keywords

CISPLATIN; CYCLOPHOSPHAMIDE;

ADOLESCENT; ADULT; AGED; ANGIOGENESIS; APOPTOSIS; ARTICLE; CELL LOSS; CELL PROLIFERATION; DNA NICK TRANSLATION; EMBRYO DEVELOPMENT; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; OVARY CANCER; PRIORITY JOURNAL; PROGNOSIS; TUMOR VASCULARIZATION;

EID: 0031884638     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.12.2.351     Document Type: Article

References (27)

1. Kerr JFR, Wyllie AH and Currie AR: Apoptosis. A basic biological phenomenon with wide-ranging implication in tissue kinetics. Br J Cancer 26: 239-257, 1972.
2. Kerr JFR, Winterford CM and Harmon BV: Apoptosis. Its significance in cancer and cancer therapy. Cancer 73: 2013-2026, 1994.
3. Ishida M, Gomyo Y, Tatebe S, Ohfuji S and Ito H: Apoptosis in human gastric mucosa, chronic gastritis, dysplasia and carcinoma: analysis by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labelling. Virchows Arch 428: 229-235, 1996.
4. Sheets EE, Crum CP and Yeh J: Association between cervical neoplasia and apoptosis as detected by in situ nuclear labeling. Gynecol Oncol 63: 94-100, 1996.
5. Lipponen P, Aaltomaa S, Kosma V-M and Syrjänen K: Apoptosis in breast cancer as related to histopathological characteristics and prognosis. Eur J Cancer 30A: 2068-2073, 1994.
6. Vesalainen S, Lipponen P, Talja M and Syrjänen K: Histological grade, perineural infiltration, tumor-infiltrating lymphocytes and apoptosis as determinants of long-term prognosis in prostatic adenocarcinoma. Eur J Cancer 30A: 1797-1803, 1994.
7. Lipponen PK and Aaltomaa S: Apoptosis in bladder cancer as related to standard prognostic factors and prognosis. J Pathol 173: 333-339, 1994.
8. Todd D, Yang G, Brown RW, Cao J, D'Agati V, Thompson TS and Truong LD: Apoptosis in renal cell carcinoma: detection by in situ end-labeling of fragmented DNA and correlation with other prognostic factors. Hum Pathol 27: 1012-1017, 1996.
9. Kiberu SW, Pringle JH, Sobolewski S, Murphy P and Lauder I: Correlation between apoptosis, proliferation and bcl-2 expression in malignant non-Hodgkin's lymphoma. J Clin Pathol 49: 268-272, 1996.
10. Lu C and Tanigawa N: Spontaneous apoptosis is inversely related to intratumoral microvessel density in gastric carcinoma. Cancer Res 57: 221-224, 1997.
11. Ponte P, Ng SY, Engel J, Gunning P and Kedes I: Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA. Nucleic Acids Res 12: 1687-1969, 1984.
12. Volm M, Mattern J and Samsel B: Overexpression of P-glycoprotein and glutathione S-transferase-pi in resistant non-small cell lung carcinomas of smokers. Br J Cancer 64: 700-704, 1991.
13. Weidner N, Semple JP, Welch WR and Folkman J: Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med 324: 1-8, 1991.
14. Cannistra SA: Cancer of the ovary. N Engl J Med 329: 1550-1559, 1993.
15. McConkey DJ, Orrenius S and Jondal M: Cellular signalling in programmed cell death (apoptosis). Immunol Today 11: 120-121, 1990.
16. Ucker PS: Death by suicide: one way to go in mammalian cellular development? New Biologist 3: 103-109, 1991.
17. Törmänen U, Eerola A-K, Rainio P, Vähäkangas K, Soini Y, Sormunen R, Bloigu R, Lehto V-P and Pääkkö P: Enhanced apoptosis predicts shortened survival in non-small cell lung carcinoma. Cancer Res 55: 5595-5602, 1995.
18. Levine EL, Renehan A, Gossiel R, Davidson SE, Roberts SA, Chadwick C, Wilks DP, Potten CS, Hendry JA, Hunter RD and West CML: Apoptosis, intrinsic radiosensitivity and prediction of radiotherapy response in cervical carcinoma. Radiother Oncol 37: 1-9, 1995.
19. Stein GS, Stein JL and Marzluff WF: Histone Genes. Structure, Organization and Regulation. Wiley, New York, 1984.
20. Kotelnikov V, Cass L, Coon JS, Spaulding D and Preisler HD: Accuracy of histone H3 messenger RNA in situ hybridization for the assessment of cell proliferation in human tissues. Clin Cancer Res 3: 669-673, 1997.
21. Schiffer D, Cavalla P, Migheli A, Chio A, Giordana MT, Marino S and Attanasio A: Apoptosis and cell proliferation in human neuroepithelial tumors. Neurosci Lett 195: 81-84, 1995.
22. Mattern J, Kallinowski F, Herfarth C and Volm M: Association of resistance-related protein expression with poor vascularization and low levels of oxygen in human rectal cancer. Int J Cancer 67: 20-23, 1996.
23. Lyng H, Sundfor K, Trope C and Rofstad EK: Oxygen tension and vascular density in human cervix carcinoma. Br J Cancer 74: 1559-1563, 1996.
24. Yao K-S, Clayton M and O'Dwyer PJ: Apoptosis in human adenocarcinoma HT29 cells induced by exposure to hypoxia. J Natl Cancer Inst 87: 117-122, 1995.
25. L. Cancer Res 56: 2161-2166, 1996.
26. Teicher BA: Hypoxia and drug resistance. Cancer Metastasis Rev 13: 139-168, 1994.
27. Moulder JE and Rockwell S: Tumor hypoxia: its impact on cancer therapy. Cancer Metastasis Rev 5: 313-341, 1987.