Urinary metabolite profile of phenyl and o-cresyl glycidyl ether in rats: Identification of a novel pathway leading to N-acetylserine O- conjugates

Chemical Research in Toxicology

Volumn 11, Issue 2, 1998, Pages 111-118

  De Rooij, Ben M ^a   Commandeur, Jan N M ^a   Hommes, John W ^a   Aalbers, Tom ^a   Groot, Ed J ^a   Vermeulen, Nico P E ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID ETHYL ESTER; ACETYLCYSTEINE DERIVATIVE; DRUG METABOLITE; EPOXIDE; ETHER DERIVATIVE; GLUTATHIONE; LACTIC ACID DERIVATIVE; MEPHENESIN; PHENYLSERINE; SERINE DERIVATIVE;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; BIOLOGICAL MONITORING; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACETYLATION; DRUG CONJUGATION; DRUG METABOLISM; DRUG URINE LEVEL; GLUTATHIONE METABOLISM; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; OCCUPATIONAL EXPOSURE; RAT; TRANSAMINATION;

ACETYLCYSTEINE; ANIMALS; BIOLOGICAL MARKERS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPOXY COMPOUNDS; GLUTATHIONE; KINETICS; LACTIC ACID; MALE; OCCUPATIONAL EXPOSURE; RATS; RATS, WISTAR; SERINE; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; COLA; PUFFINUS AURICULARIS;

EID: 0031884544     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx970020n     Document Type: Article

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