Developmental gene expression of sympathetic nervous system tumors reflects their histogenesis

Laboratory Investigation

Volumn 78, Issue 1, 1998, Pages 29-45

  Hoehner, Jeff C ^a   Hedborg, Fredrik ^a   Eriksson, Lars ^a   Sandstedt, Bengt ^b   Grimelius, Lars ^a   Olsen, Leif ^a   Påhlman, Sven ^c  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADRENERGIC SYSTEM; ADULT; AGED; ARTICLE; CARCINOGENESIS; CHILD; CLINICAL ARTICLE; EMBRYO; FEMALE; FETUS; GENE EXPRESSION; HISTOGENESIS; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; INFANT; MALE; MARKER GENE; NERVOUS SYSTEM TUMOR; NEUROBLASTOMA; NEWBORN; PARAGANGLIOMA; PHEOCHROMOCYTOMA; PRIORITY JOURNAL; STEM CELL;

EID: 0031883780     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (97)

1. Adams GA, Shochat SJ, Smith EI, Shuster JJ, Joshi VV, Altshuler G, Hayes FA, Nitschke R, McWilliams N, and Castleberry RP (1993). Thoracic neuroblastoma: A pediatric oncology group study. J Pediatr Surg 28:372-378.
2. Ambros IM and Ambros PF (1995). Schwann cells in neuroblastoma. Eur J Cancer 31A:429-434.
3. Barontini M, Gutierrez MI, Levin G, Mur N, and Diez B (1993). N-myc oncogene and urinary catecholamines in children with neuroblastoma. Med Pediatr Oncol 21:499-504.
4. Beard MC, Sheps SG, Kurland LT, Carney JA, and Lei JT (1983). Occurrence of pheochromocytoma in Rochester, Minnesota, 1950-1979. Mayo Clin Proc 58:802-804.
5. Beckwith JB and Martin RF (1968). Observations on the histologic theory of neuroblastomas. J Pediatr Surg 3:106-110.
6. Beckwith JB and Perrin E (1962). In situ neuroblastomas: A contribution to the natural history of neural crest tumours. Am J Pathol 43:1089-1104.
7. Bravo EL, Tarazi RC, Gifford RW, and Stewart BH (1979). Circulating and urinary catecholamines in pheochromocytoma. N Engl J Med 301:682-686.
8. Brodeur G, Pritchard J, Berthold F, Carlsen N, Castel V, Castleberry R, DeBernardi B, Evans A, Favrot M, Hedborg F, Kaneko M, Kemshead J, Lampert F, Lee R, Look T, Pearson A, Philip T, Roald B, Sawada T, Seeger R, Tsuchida Y, and Voute P (1993). Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol 11:1466-1477.
9. Bronner-Fraser M (1987). Perturbation of cranial neural crest migration by the HNK-1 antibody. Dev Biol 123:321-331.
10. Ciccarone V, Spengler BA, Meyers MB, Biedler JL, and Ross RA (1989). Phenotypic diversification in human neuroblastoma cells: Expression of distinct neural crest lineages. Cancer Res 49:219-225.
11. Coldman AJ, Fryer CJH, Elwood JM, and Sonley MJ (1980). Neuroblastoma: Influence of age at diagnosis, stage, tumor site and sex on prognosis. Cancer 46:1896-1901.
12. Cooper MJ, Hutchins GM, Cohen PS, Helman LJ, Mennie RJ, and Israel MA (1990a). Human neuroblastoma tumor cell lines correspond to the arrested differentiation of chromaffin adrenal medullary neuroblasts. Cell Growth Differ 1:149-159.
13. Cooper MJ, Hutchins GM, and Israel MA (1990b). Histogenesis of the human adrenal medulla: An evaluation of the ontogeny of chromaffin and nonchromaffin lineages. Am J Pathol 137:605-615.
14. Cooper MJ, Steinberg SM, Chatten J, Evans AE, and Israel MA (1992). Plasticity of neuroblastoma tumor cells to differentiate along a fetal adrenal ganglionic lineage predicts for improved patient survival. J Clin Invest 90:2402-2408.
15. Costero L and Chevez AZ (1962). Carotid body tumor in tissue culture. Am J Pathol 40:337-357.
16. Coupland R (1952). The prenatal development of the abdominal para-aortic bodies in man. J Anat 86:357-372.
17. Coupland R (1965). The natural history of the chromaffin cell. London: Longmans Green.
18. Coupland R (1980). The development and fate of catecholamine secreting endocrine cells. In: Parvis H and Parvis S, editors: Biogenic amines in development. Amsterdam: Elsevier/North-Holland, 3-28.
19. Crowder RE (1957). The development of the adrenal gland in man, with special reference to the origin and ultimate location of cell types and evidence in favor of the "cell migration theory." Carnegie Inst Contrib Embryol 36:195-210.
20. Cushing H and Wolbach SB (1927). The transformation of a malignant paravertebral sympathicoblastoma into a benign ganglioneuroma. Am J Pathol 3:203-209.
21. Dixon JS, Gosling JA, Canning DA, and Gearhart JP (1992). An immunohistochemical study of human postnatal paraganglia associated with the urinary bladder. J Anat 181:431-436.
22. Donovan MJ, Hempstead BL, Horvath C, Chao MV, and Schofield D (1993). Immunohistochemical localization of Trk receptor protein in pediatric small round blue cell tumors. Am J Pathol 143:1560-1567.
23. Doupe AJ, Landis SC, and Patterson PH (1985a). Environmental influences in the development of neural crest derivatives: Glucocorticoids, growth factors, and chromaffin cell plasticity. J Neurosci 5:2119-2142.
24. Doupe AJ, Patterson PH, and Landis SC (1985b). Small intensely fluorescent cells in culture: Role of glucocorticoids and growth factors in their development and interconversions with other neural crest derivatives. J Neurosci 5:2143-2160.
25. Eide FF, Lowenstein DH, and Reichardt LF (1993). Neurotrophins and their receptors: Current concepts and implications for neurologic disease. Exp Neurol 121:200-214.
26. Eränkö L and Eränkö O (1972). Effect of hydrocortisone on histochemically demonstrable catecholamines in the sympathetic ganglia and extra-chromaffin tissue of the rat. Acta Physiol Scand 84:125-133.
27. Ernfors P, Merlio J, and Persson H (1992). Cells expressing mRNA for neurotrophins and their receptors during embryonic rat development. Eur J Neurosci 4:1140-1158.
28. Evans AE, Albo V, and D'Angio GJ (1976). Factors influencing survival of children with nonmetastatic neuroblastoma. Cancer 38:661-666.
29. Evans AE, D'Angio GJ, and Randolph JA (1971). A proposed staging for children with neuroblastoma. Cancer 27:374-378.
30. Evans AE, D'Angio GJ, Propert K, Anderson J, and Hann H-W (1987). Prognostic factors in neuroblastoma. Cancer 59:1853-1859.
31. Fraga M, Garcia-Caballero T, Anuntez J, Couce M, Beiras A, and Forteza J (1993). A comparative immunohistochemical study of phaeochromocytomas and paragangliomas. Histol Histopathol 8:429-436.
32. Gestblom C, Hoehner JC, Hedborg F, Sandstedt B, and Påhlman S (1997). In vivo spontaneous neuronal and cellular death in clinical neuroblastoma. Am J Pathol 150:107-117.
33. Gitlow SE, Dziedzic LB, Strauss L, Greenwood SM, and Dziedzic SW (1973). Biochemical and histologic determinants in the prognosis of neuroblastoma. Cancer 32:898-905.
34. Greenfield LJ and Shelley WM (1965). The spectrum of neurogenic tumors of the sympathetic nervous system: Maturation and adrenergic function. J Natl Cancer Inst 35:215-226.
35. Gross N, Beretta C, Peruisseau G, Jackson D, Simmons D, and Beck D (1994). CD44H expression by human neuroblastoma cells: Relation to MYCN amplification and lineage differentiation. Cancer Res 54:4238-4242.
36. Haselbacher GK, Irminger JC, Zapf J, Ziegler WH, and Humbel RE (1987). Insulin-like growth factor II in adrenal pheochromocytomas and Wilms tumors: Expression at the mRNA and protein level. Proc Natl Acad Sci USA 84:1104-1106.
37. Hedborg F, Bjelfman C, Sparen P, Sandstedt B, and Påhlman S (1995a). Biochemical evidence for a mature phenotype in morphologically poorly differentiated neuroblastomas with favourable outcome. Eur J Cancer 31A:435-443.
38. Hedborg F, Ohlsson R, Sandstedt B, Grimelius L, Hoehner JC, and Påhlman S (1995b). IGF2 expression is a marker for paraganglionic/SIF cell differentiation in neuroblastoma. Am J Pathol 146:833-847.
39. Hoehner JC, Hedborg F, Sandstedt B, Olsen L, and Påhlman S (1995a). Cellular death in neuroblastoma: In situ correlation of apoptosis and Bcl-2 expression. Int J Cancer 62:19-24.
40. Hoehner JC, Olsen L, Sandstedt B, Kaplan DR, and Påhlman S (1995b). Association of neurotrophin receptor expression and differentiation in human neuroblastoma. Am J Pathol 147:102-113.
41. Hoehner JC, Gestblom C, Hedborg F, Sandstedt B, Olsen L, and Påhlman S (1996). A developmental model of neuroblastoma: Differentiating stroma-poor tumors progress along an extra-adrenal chromaffin lineage. Lab Invest 75: 659-675.
42. Honma K (1994). Paraganglia of the urinary bladder: An autopsy study. Zentralbl Pathol 139:465-469.
43. Ikeda Y, Lister J, Bouton JM, and Buyukpamukcu M (1981). Congenital neuroblastoma, neuroblastoma in situ, and the normal fetal development of the adrenal. J Pediatr Surg 16:636-644.
44. Joshi VV and Silverman JF (1994). Pathology of neuroblastic tumors. Semin Diagn Pathol 11:107-117.
45. Kaufman BH, Telander RL, van Heerden JA, Zimmerman D, Sheps SG, and Dawson B (1983). Pheochromocytoma in the pediatric age group: Current status. J Pediatr Surg 18:879-884.
46. Kimura N, Miura Y, Nagatsu I, and Nagura H (1992). Catecholamine synthesizing enzymes in 70 cases of functioning and non-functioning phaeochromocytoma and extra-adrenal paraganglioma. Virchows Arch A Pathol Anat Histopathol 421:25-32.
47. Kinnier Wilson LM and Draper GJ (1974). Neuroblastoma, its natural history and prognosis: A study of 487 cases. Br Med J 3:301-307.
48. Kliewer KE, Wen D-R, Cancilla PA, and Cochran AJ (1989). Paragangliomas: Assessment of prognosis by histologic, immunohistochemical, and ultrastructural techniques. Hum Pathol 20:29-39.
49. Kogut MD and Kaplan SA (1962). Systemic manifestations of neurogenic tumors. J Pediatr 60:694-704.
50. Krajewski S, Chatten J, Hanada M, and Reed JC (1995). Immunohistochemical analysis of the bcl-2 oncoprotein in human neuroblastomas: Comparisons with tumor cell differentiation and N-Myc protein. Lab Invest 71:42-52.
51. LaBrosse EH, Comoy E, Bohuon C, Zucker J-M, and Schweisguth O (1976). Catecholamine metabolism in neuroblastoma. J Natl Cancer Inst 57:633-638.
52. LaBrosse EH, Com-Nougue C, Zucker J-M, Comoy E, Bohuon C, Lemerle J, and Schweisguth O (1980). Urinary excretion of 3-methoxy-4-hydroxymandelic acid and 3-methoxy-4-hydroxyphenylacetic acid by 288 patients with neuroblastoma and related neural crest tumors. Cancer Res 40:1995-2001.
53. Lack EE, Cubilla AL, Woodruff JM, and Lieberman PH (1980). Extra-adrenal paragangliomas of the retroperitoneum: A clinicopathologic study of 12 tumors. Am J Surg Pathol 4:109-120.
54. Laug WE, Siegel SE, Shaw KN, Landing B, Baptista J, and Gutenstein M (1978). Initial urinary catecholamine metabolite concentrations and prognosis in neuroblastoma. Pediatrics 62:77-83.
55. Lavenius E, Gestblom C, Johansson I, Nånberg E, and Påhlman S (1995). Transfection of trk-A into human neuroblastoma cells restores their ability to differentiate in response to nerve growth factor. Cell Growth Differ 6:727-736.
56. Le Douarin NM, Dupin E, Baroffio A, and Dulac C (1992). New insights into the development of neural crest derivatives. Int Rev Cytol 138:269-314.
57. Leestma JE and Price EB (1971). Paraganglioma of the urinary bladder. Cancer 18:1063-1073.
58. Linnoila RI, Keiser HR, Steinberg SM, and Lack EE (1990). Histopathology of benign versus malignant sympathoadrenal paragangliomas: Clinicopathologic study of 120 cases including unusual histologic features. Hum Pathol 21:1168-1180.
59. Lloyd RV, Sisson JC, Shapiro B, and Verhofstad AAJ (1986). Immunohistochemical localization of epinephrine, norepinephrine, catecholamine-synthesizing enzymes, and chromogranin in neuroendocrine cells and tumors. Am J Pathol 125:45-54.
60. Lucas K, Gula MJ, Knisely AS, Virgi MA, Wollman M, and Blatt J (1994). Catecholamine metabolites in ganglioneuroma. Med Pediatr Oncol 22:240-243.
61. Manger WM and Gifford RW (1977). Pheochromocytoma. New York: Springer-Verlag.
62. Martin-Zanca D, Barbacid M, and Parada LF (1990). Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development. Genes Dev 4:683-694.
63. Melicow MM (1977). One hundred cases of pheochromocytomas (107 tumors) at the Columbia-Presbyterian Medical Center. Cancer 40:1987-2004.
64. Molenaar WM, Baker DL, Pleasure D, Lee VM, and Trojanowski JQ (1990a). The neuroendocrine and neural profiles of neuroblastomas, ganglioneuroblastomas, and ganglioneuromas. Am J Pathol 136:375-382.
65. Molenaar WM, Lee VM-Y, and Trojanowski JQ (1990b). Early fetal acquisition of the chromaffin and neuronal immunophenotype by human adrenal medullary cells. An immunohistological study using monoclonal antibodies to chromogranin A, synaptophysin, tyrosine hydroxylase, and neuronal cytoskeletal proteins. Exp Neurol 108:1-9.
66. Moran CA, Suster S, Fishback N, and Koss MN (1993). Mediastinal paragangliomas: A clinicopathologic and immunohistochemical study of 16 cases. Cancer 72:2358-2364.
67. Morris JA, Shochat SJ, Smith EI, Look AT, Brodeur GM, Cantor AB, and Castleberry RP (1995). Biological variables in thoracic neuroblastoma: A pediatric oncology group study. J Pediatr Surg 30:296-303.
68. Nakagawara A, Asima-Nakagawara M, Scavarda NJ, Azar CG, Cantor AB, and Brodeur GM (1993). Association between high levels of expression of the trk gene and favourable outcome in human neuroblastoma. N Engl J Med 328:847-854.
69. Nitschke R, Smith E, and Shochat S (1988). Localized neuroblastoma treated by surgery: A pediatric oncology group study. J Clin Oncol 6:1271-1278.
70. Örtoft E, Bjelfman C, Hedborg F, Grimelius L, and Påhlman S (1995). The expression profile of alternatively spliced neuronal c-src RNA distinguishes between human tumours of the sympatho-adrenal lineage. Int J Cancer 60:38-44.
71. Påhlman S, Hoehner JC, Nånberg E, Hedborg F, Fagerström S, Gestblom C, Johansson I, Larsson U, Lavenius E, Örtoft E, and Söderholm H (1995). Differentiation and survival influences of growth factors in human neuroblastoma. Eur J Cancer 31A:453-458.
72. Pryse-Davies JI, Dawson IMP, and Westbury G (1964). Some morphologic, histochemical and chemical observations on chemodectomas and the normal carotid body, including a study of the chromaffin reaction and possible ganglion cell elements. Cancer 17:195-202.
73. Schmitt HP, Wurster K, Bauer M, and Paroch K (1982). Mixed chemodectoma ganglioneuroma of the conus medularis region. Acta Neuropathol (Berl) 57:275-281.
74. Seidl K and Unsicker K (1989). Survival and neuritic growth of sympathoadrenal (chromaffin) precursor cells in vitro. Int J Dev Neurosci 7:465-473.
75. Sherwin RP (1959). Histopathology of pheochromocytoma. Cancer 12:861-877.
76. Shimada H, Chatten J, Newton WA, Sachs N, Hamoudi A, Chiba T, Marsden H, and Misugi K (1984). Histopathologic prognostic factors in neuroblastoma tumors: Definition of subtypes of ganglioneuroblastoma and an age linked classification of neuroblastoma. J Natl Cancer Inst 73:405-416.
77. Shimada H, Aoyama C, Chiba T, and Newton WAJ (1985). Prognostic subgroups for undifferentiated neuroblastoma: Immunohistochemical study with anti-S-100 protein antibody. Hum Pathol 16:471-476.
78. Siegel SE, Laug WE, Harlow PJ, Shaw KNF, Landing B, and Gutenstein M (1980). Patterns of urinary catecholamine metabolite excretion in neuroblastoma. In: Evans AE, editor: Advances in neuroblastoma research. New York: Raven Press, 25-32.
79. Stout AP (1947). Ganglioneuroma of the sympathetic nervous system. Surg General Obstet 84:101-109.
80. Stowens D (1959). Neuroblastoma and related tumors. Arch Pathol 63:451-459.
81. Suzuki T, Watanabe K, Sugino T, Tanigawa T, and Satoh S (1992). Immunocytochemical demonstration of IGF-II immunoreactivity in human phaeochromocytoma and extra-adrenal abdominal paraganglioma. J Pathol 167:199-203.
82. Suzuki T, Bogenmann E, Shimada H, Stram D, and Seeger RC (1993). Lack of high-affinity nerve growth factor receptors in aggressive neuroblastomas. J Natl Cancer Inst 85:377-384.
83. Terpe HJ, Stark H, Prehm P, and Gunthert U (1994). CD44 variant isoforms are preferentially expressed in basal epithelia of non-malignant human fetal and adult tissues. Histochemistry 101:79-89.
84. Terpe HJ, Christiansen H, Gonzalez M, Berthold F, and Lampert F (1995). Differentiation and prognosis of neuroblastoma in correlation to the expression of CD44s. Eur J Cancer 31A:549-552.
85. Tischler AS (1991). The adrenal medulla and extra-adrenal paraganglia. In: Kovacs K and Asa S, editors: Functional endocrine pathology. St. Louis: Blackwell Scientific Publications, 509-545.
86. Tischler AS, Dichter MA, Biales B, DeLellis RA, and Wolfe H (1976). Neural properties of cultured human endocrine tumors cells of proposed neural crest origin. Science 192:902-904.
87. Tischler AS, Dichter MA, Biales B, and Greene LA (1977). Neuroendocrine neoplasms and their cells of origin. N Engl J Med 296:919-924.
88. Tischler AS, Lee AK, Nunnemacher G, Said S, DeLellis RA, and Morse GM (1981). Spontaneous neurite outgrowth and vasoactive intestinal peptide-like immunoreactivity in cultures of human paraganglioma cells from the glomus jugulare. Cell Tissue Res 219:543-555.
89. Tischler AS, Lee YC, Perlman RL, Costopoulos D, Slayton VW, and Bloom SR (1984). Production of ectopic vasoactive intestinal peptide like and neurotensin like immunoreactivity in human pheochromocytoma cell cultures. J Neurosci 4:1398-1404.
90. Tischler AS, Dayal Y, Balogh K, Cohen RB, Connolly JL, and Tallberg K (1987). The distribution of immunoreactive chromogranins, S-100 protein and vasoactive intestinal peptide in compound tumors of the adrenal medulla. Hum Pathol 18: 909-917.
91. Tsokos M, Scarpa S, Ross RA, and Triche TJ (1987). Differentiation of human neuroblastoma recapitulates neural crest development: Study of morphology, neurotransmitter enzymes, and extracellular matrix proteins. Am J Pathol 128: 484-496.
92. Turkel SB and Itabashi HH (1974). The natural history of neuroblastic cells in the fetal adrenal gland. Am J Pathol 76:225-244.
93. Unsicker K, Krisch B, Otten U, and Thoenen H (1978). Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: Impairment by glucocorticoids. Proc Natl Acad Sci USA 75:3498-3502.
94. Unsicker K, Skaper SD, and Varon S (1985). Neuronotrophic and neurite-promoting factors: Effects on early postnatal chromaffin cells from adrenal medulla. Dev Brain Res 17: 117-129.
95. Vaux DL (1993). Toward an understanding of the molecular mechanisms of physiological cell death. Proc Natl Acad Sci USA 90:786-789.
96. von Studnitz W, Käser H, and Sjoerdsma A (1963). Spectrum of catechol amine biochemistry in patients with neuroblastoma. N Engl J Med 269:232-235.
97. Zuckerkandl E (1912). The development of the chromaffin organs and the suprarenal glands. Philadelphia: Lippincott.