The major site of phosphorylation within the Rous sarcoma virus MA protein is not required for replication

Journal of Virology

Volumn 72, Issue 2, 1998, Pages 1103-1107

  Nelle, Timothy D ^a,c   Verderame, Michael F ^a   Leis, Jonathan ^b   Wills, John W ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c U States Army Med Res Inst I   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TYROSINE;

ARTICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ROUS SARCOMA ONCOVIRUS; VIROGENESIS; VIRUS INFECTIVITY; VIRUS REPLICATION;

EID: 0031883553     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.2.1103-1107.1998     Document Type: Article

References (33)

1. Bennett, R. P., T. D. Nelle, and J. W. Wills. 1993. Functional chimeras of the Rous sarcoma virus and human immunodeficiency virus Gag proteins. J. Virol. 67:6487-6498.
2. Bennett, R. P., S. Rhee, R. C. Craven, E. Hunter, and J. W. Wills. 1991. Amino acids encoded downstream of gag are not required by Rous sarcoma virus protease during Gag-mediated assembly. J. Virol. 65:272-280.
3. Bukrinsky, M. I., S. Haggerty, M. P. Dempsey, N. Sharova, A. Adzhubel, L. Spitz, P. Lewis, D. Goldfarb, M. Emerman, and M. Stevenson. 1993. A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells. Nature 365:666-669.
4. Craven, R. C., R. P. Bennett, and J. W. Wills. 1991. Role of the avian retroviral protease in the activation of reverse transcriptase during virion assembly. J. Virol. 65:6205-6217.
5. Craven, R. C., D. A. Leure, C. R. Erdie, C. B. Wilson, and J. W. Wills. 1993. Necessity of the spacer peptide between CA and NC in the Rous sarcoma virus Gag protein. J. Virol. 67:6246-6252.
6. Craven, R. C., D. A. Leure, R. J. Weldon, and J. W. Wills. 1995. Genetic analysis of the major homology region of the Rous sarcoma virus Gag protein. J. Virol. 69:4213-4227.
7. Depaoli-Roach, A. A., I. K. Park, V. Cerovsky, C. Csortos, S. D. Durbin, M. J. Kuntz, A. Sitikov, P. M. Tang, A. Verin, and S. Zolnierowicz. 1994. Serine/ threonine protein phosphatases in the control of cell function. Adv. Enzyme Regul. 34:199-224.
8. Dong, J. Y., J. W. Dubay, L. G. Perez, and E. Hunter. 1992. Mutations within the proteolytic cleavage site of the Rous sarcoma virus glycoprotein define a requirement for dibasic residues for intracellular cleavage. J. Virol. 66:865-874.
9. Erdie, C. R., and J. W. Wills. 1990. Myristylation of Rous sarcoma virus Gag protein does not prevent replication in avian cells. J. Virol. 64:5204-5208.
10. Erikson, E., J. S. Brugge, and R. L. Erikson. 1977. Phosphorylated and nonphosphorylated forms of avian sarcoma virus polypeptide p19. Virology 80:177-185.
11. Fu, X., N. Phillips, J. Jentoft, P. T. Tuazon, J. A. Traugh, and J. Leis. 1985. Site-specific phosphorylation of avian retrovirus nucleocapsid protein pp12 regulates binding to viral RNA. Evidence for different protein conformations. J. Biol. Chem. 260:9941-9947.
12. Fu, X. D., P. T. Tuazon, J. A. Traugh, and J. Leis. 1988. Site-directed mutagenesis of the avian retrovirus nucleocapsid protein, pp12, at serine 40, the primary site of phosphorylation in vivo. J. Biol. Chem. 263:2134-2139.
13. Gallay, P., V. Stitt, C. Mundy, M. Oettinger, and D. Trono. 1996. Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import. J. Virol. 70:1027-1032.
14. Gallay, P., S. Swingler, C. Aiken, and D. Trono. 1995. HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator. Cell 80:379-388.
15. Gallay, P., S. Swingler, J. P. Song, F. Bushman, and D. Trono. 1995. HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase. Cell 83:569-576.
16. Hizi, A., and W. K. Joklik. 1977. The beta subunit of the DNA polymerase of avian sarcoma virus strain B77 is a phosphoprotein. Virology 78:571-575.
17. Hunter, E. 1994. Biological techniques for avian sarcoma viruses. Methods Enzymol. 58:379-392.
18. Lai, M. M. 1976. Phosphoproteins of Rous sarcoma viruses. Virology 74: 287-301
19. Leis, J., S. Johnson, L. S. Collins, and J. A. Traugh. 1984. Effects of phosphorylation of avian retrovirus nucleocapsid protein pp12 on binding of viral RNA. J. Biol. Chem. 259:7726-7732.
20. Leis J., N. Phillips, X. Fu, P. T. Tuazon, and J. A. Traugh. 1989. Phosphorylation of avian retrovirus matrix protein by Ca2+/phospholipid-dependent protein kinase. Eur. J. Biochem. 179:415-422.
21. Nelle, T. D., and J. W. Wills. 1996. A large region within the Rous sarcoma virus matrix protein is dispensable for budding and infectivity. J. Virol. 70:2269-2276.
22. Parent, L. J., C. B. Wilson, M. D. Resh, and J. W. Wills. 1996. Evidence for a second function of the MA sequence in the Rous sarcoma virus Gag protein. J. Virol. 70:1016-1026.
23. Pepinsky, R. B., I. A. Papayannopoulos, S. Campbell, and V. M. Vogt. 1996. Analysis of Rous sarcoma virus Gag protein by mass spectrometry indicates trimming by host exopeptidase. J. Virol. 70:3313-3318.
24. Pinna, L. A., and M. Ruzzene. 1996. How do protein kinases recognize their substrates? Biochim. Biophys. Acta 1314:191-225.
25. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
26. Schiff, R. D., and D. P. Grandgenett. 1980. Partial phosphorylation in vivo of the avian retrovirus pp32 DNA endonuclease. J. Virol. 36:889-893.
27. Schwartz, D. E., R. Tizard, and W. Gilbert. 1983. Nucleotide sequence of Rous sarcoma virus. Cell 32:853-869.
28. Shealy, D. J., A. G. Mosser, and R. R. Rueckert. 1980. Novel p19-related protein in Rous-associated virus type 61: implications for avian gag gene order. J. Virol. 34:431-437.
29. Vogt, P. K. 1969. Focus assay of Rous Sarcoma virus, p. 198-211. In H. K. and N. P. Salzman (ed.), Fundamental techniques of virology. Academic Press, New York, N.Y.
30. Weldon, R. J., C. R. Erdie, M. G. Oliver, and J. W. Wills. 1990. Incorporation of chimeric Gag protein into retroviral particles. J. Virol. 64:4169-4179.
31. Wills, J. W., and R. C. Craven. 1991. Form, function, and use of retroviral Gag proteins. AIDS 5:639-654.
32. Wills, J. W., R. C. Craven, and J. A. Achacoso. 1989. Creation and expression of myristylated forms of Rous sarcoma virus Gag protein in mammalian cells. J. Virol. 63:4331-4343.
33. src. J. Virol. 65:3804-3812.