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Volumn 100, Issue 4, 1998, Pages 698-703

Fas-mediated apoptosis with normal expression of bcl-2 and p53 in lymphocytes from aplastic anaemia

Author keywords

Aplastic anaemia; Apoptosis; bcl 2; Fas receptor; Flow cytometry; P53

Indexed keywords

FAS ANTIGEN; FAS LIGAND; MEMBRANE PROTEIN; PROTEIN BCL 2; PROTEIN P53;

EID: 0031881380     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.00625.x     Document Type: Article
Times cited : (16)

References (38)
  • 2
    • 0028048353 scopus 로고
    • T cell receptor-induced Fas ligand expression in cytotoxic T lymphocyte clone is blocked by protein tyrosine kinase inhibitors and cyclosporine A
    • Anel, A., Buferne, M., Boyer, C., Schmitt-Verhulst, A.M., & Golstein, P. (1994) T cell receptor-induced Fas ligand expression in cytotoxic T lymphocyte clone is blocked by protein tyrosine kinase inhibitors and cyclosporine A. European Journal of Immunology, 24, 2469-2476.
    • (1994) European Journal of Immunology , vol.24 , pp. 2469-2476
    • Anel, A.1    Buferne, M.2    Boyer, C.3    Schmitt-Verhulst, A.M.4    Golstein, P.5
  • 4
    • 0026688162 scopus 로고
    • Apoptotic cell death induced by c-myc is inhibited by bcl-2
    • Bissonete, R.P., Echeverri, E. Mahboudi, A. & Gren, D.R. (1992) Apoptotic cell death induced by c-myc is inhibited by bcl-2. Nature, 359, 552-554.
    • (1992) Nature , vol.359 , pp. 552-554
    • Bissonete, R.P.1    Echeverri, E.2    Mahboudi, A.3    Gren, D.R.4
  • 5
    • 0030031677 scopus 로고    scopus 로고
    • Complete remission in severe aplastic anemia after high-dose cyclophosphamide without bone marrow transplantation
    • Brodsky, R.A., Sensenbrenner, L.L. & Jones, R.R. (1996) Complete remission in severe aplastic anemia after high-dose cyclophosphamide without bone marrow transplantation. Blood, 87, 491-497.
    • (1996) Blood , vol.87 , pp. 491-497
    • Brodsky, R.A.1    Sensenbrenner, L.L.2    Jones, R.R.3
  • 6
    • 0030805088 scopus 로고    scopus 로고
    • Increased apoptotic cells in bone marrow biopsies from patients with aplastic anaemia
    • Callera, F. & Falcão, R.P. (1997) Increased apoptotic cells in bone marrow biopsies from patients with aplastic anaemia. British Journal of Haematology, 98, 18-20.
    • (1997) British Journal of Haematology , vol.98 , pp. 18-20
    • Callera, F.1    Falcão, R.P.2
  • 7
    • 0012318722 scopus 로고
    • Increased Fas antigen expression on lymphocytes from severe aplastic anemia
    • Callera, F. Garcia, A.B. & Falcão, R.P. (1995) Increased Fas antigen expression on lymphocytes from severe aplastic anemia. Blood, 86, 478a-1898.
    • (1995) Blood , vol.86
    • Callera, F.1    Garcia, A.B.2    Falcão, R.P.3
  • 8
    • 0026680874 scopus 로고
    • Apoptosis and programmed cell death in immunity
    • Cohen, J.J. & Duke, R.C. (1992) Apoptosis and programmed cell death in immunity. Annual Review of Immunology, 10, 267-293.
    • (1992) Annual Review of Immunology , vol.10 , pp. 267-293
    • Cohen, J.J.1    Duke, R.C.2
  • 9
    • 0028238410 scopus 로고
    • Activation induces sensitivity toward APO-1 (CD95)-mediated apoptosis in human B cells
    • Daniel, P.T. & Krammer, P.H. (1994) Activation induces sensitivity toward APO-1 (CD95)-mediated apoptosis in human B cells. Journal of Immunology, 152, 5624-5632.
    • (1994) Journal of Immunology , vol.152 , pp. 5624-5632
    • Daniel, P.T.1    Krammer, P.H.2
  • 12
    • 0022003457 scopus 로고
    • T-lymphocyte subpopulations in the peripheral blood and bone marrow of patients with aplastic anemia
    • Falcão, R.P., Voltarelli, J.C. & Bottura, C. (1985) T-lymphocyte subpopulations in the peripheral blood and bone marrow of patients with aplastic anemia. Blut, 50, 103-107.
    • (1985) Blut , vol.50 , pp. 103-107
    • Falcão, R.P.1    Voltarelli, J.C.2    Bottura, C.3
  • 14
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery, D.M., Nunez, G., Milliman, C., Schreiber, R.D. & Korsmeyer, S.J. (1990) Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature, 348, 334-336.
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.M.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 15
    • 0027161158 scopus 로고
    • Effect of bcl-2 on Fas antigen-mediated cell death
    • Itoh, N., Tsujimoto, Y. & Nagata, S. (1993) Effect of bcl-2 on Fas antigen-mediated cell death. Journal of Immunology, 151, 621-627.
    • (1993) Journal of Immunology , vol.151 , pp. 621-627
    • Itoh, N.1    Tsujimoto, Y.2    Nagata, S.3
  • 17
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr, J.F.R., Wyllie, A.H. & Currie, A.R. (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. British Journal of Cancer, 36, 239-257.
    • (1972) British Journal of Cancer , vol.36 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 18
    • 0028883850 scopus 로고
    • Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
    • Kischkel, F.C., Hellbardt, S., Behrmann, I., Germer, M., Pawlita, M., Krammer, P.H. & Peter, M.E. (1995) Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO Journal, 14, 5579-5588.
    • (1995) EMBO Journal , vol.14 , pp. 5579-5588
    • Kischkel, F.C.1    Hellbardt, S.2    Behrmann, I.3    Germer, M.4    Pawlita, M.5    Krammer, P.H.6    Peter, M.E.7
  • 19
    • 0029913687 scopus 로고    scopus 로고
    • Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis
    • Lagresle, C., Mordiere, P., Bella, C., Krammer, P.H. & Defrance, T. (1996) Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis. Journal of Experimental Medicine, 183, 1377-1388.
    • (1996) Journal of Experimental Medicine , vol.183 , pp. 1377-1388
    • Lagresle, C.1    Mordiere, P.2    Bella, C.3    Krammer, P.H.4    Defrance, T.5
  • 20
    • 0030037138 scopus 로고    scopus 로고
    • Bcl-2 protects against Fas-based but not perforin-based T cell-mediated cytolysis
    • Lee, R.K., Spielman, J. & Podack, E.R. (1996) Bcl-2 protects against Fas-based but not perforin-based T cell-mediated cytolysis. International Immunology, 8, 991-1000.
    • (1996) International Immunology , vol.8 , pp. 991-1000
    • Lee, R.K.1    Spielman, J.2    Podack, E.R.3
  • 21
    • 0025876591 scopus 로고
    • The p53 tumour suppressor gene
    • Levine, A.J., Momand, J. & Finlay, C.A. (1991) The p53 tumour suppressor gene, Nature, 351, 453-456.
    • (1991) Nature , vol.351 , pp. 453-456
    • Levine, A.J.1    Momand, J.2    Finlay, C.A.3
  • 22
    • 0028802845 scopus 로고
    • Fas and FasL in the homeostatic regulation of immune responses
    • Lynch, D.H., Ramsdell, F. & Alderson, M.R. (1995) Fas and FasL in the homeostatic regulation of immune responses. Immunology Today, 16, 569-574.
    • (1995) Immunology Today , vol.16 , pp. 569-574
    • Lynch, D.H.1    Ramsdell, F.2    Alderson, M.R.3
  • 24
    • 0026497684 scopus 로고
    • Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood
    • Miyawaki, T., Uehara, T., Nibu, R., Tsuji, T., Yachie, A., Yonehara, S. & Taniguchi, N. (1992) Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. Journal of Immunology, 149, 3753-3758.
    • (1992) Journal of Immunology , vol.149 , pp. 3753-3758
    • Miyawaki, T.1    Uehara, T.2    Nibu, R.3    Tsuji, T.4    Yachie, A.5    Yonehara, S.6    Taniguchi, N.7
  • 25
    • 0028927607 scopus 로고
    • The Fas death factor
    • Nagata, S. & Golstein, P. (1995) The Fas death factor. Science, 267, 1449-1456.
    • (1995) Science , vol.267 , pp. 1449-1456
    • Nagata, S.1    Golstein, P.2
  • 26
  • 27
    • 0029609759 scopus 로고
    • Increased apoptosis in aplastic anemia bone marrow progenitor cells: Possible pathophysiologic significance
    • Philpott, N.J., Scopes, J., Marsch, J.C.W., Gordon-Smith, E.C. & Gibson, F.M. (1995) Increased apoptosis in aplastic anemia bone marrow progenitor cells: possible pathophysiologic significance. Experimental Haematalogy, 23, 1642-1648.
    • (1995) Experimental Haematalogy , vol.23 , pp. 1642-1648
    • Philpott, N.J.1    Scopes, J.2    Marsch, J.C.W.3    Gordon-Smith, E.C.4    Gibson, F.M.5
  • 28
    • 0026582064 scopus 로고
    • Sequential paraformaldehyde and metanol fixation for simultaneous flow cytometric analysis of DNA, cell surface proteins and intracellular proteins
    • Pollice, A.A., McCoy, J.P., Shackney, S.E., Smith, C.A., Agarwal, J. & Burholt, D.R. (1992) Sequential paraformaldehyde and metanol fixation for simultaneous flow cytometric analysis of DNA, cell surface proteins and intracellular proteins. Cytometry, 13, 432-444.
    • (1992) Cytometry , vol.13 , pp. 432-444
    • Pollice, A.A.1    McCoy, J.P.2    Shackney, S.E.3    Smith, C.A.4    Agarwal, J.5    Burholt, D.R.6
  • 29
    • 0028129894 scopus 로고
    • Effects of the lpr mutation on elimination and inactivation of self-reactive B cells
    • Rathmell, J.C. & Goodnow, C.C. (1994) Effects of the lpr mutation on elimination and inactivation of self-reactive B cells. Journal of Immunology, 153, 2831-2842.
    • (1994) Journal of Immunology , vol.153 , pp. 2831-2842
    • Rathmell, J.C.1    Goodnow, C.C.2
  • 30
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed, J.C (1994) Bcl-2 and the regulation of programmed cell death. Journal of Cell Biology, 124, 1-6.
    • (1994) Journal of Cell Biology , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 32
    • 0029609086 scopus 로고
    • Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
    • Strasser, A., Harris, A.W., Huang, D.C.S., Krammer, P.H. & Cory, S. (1995) Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO Journal, 14, 6136-6147.
    • (1995) EMBO Journal , vol.14 , pp. 6136-6147
    • Strasser, A.1    Harris, A.W.2    Huang, D.C.S.3    Krammer, P.H.4    Cory, S.5
  • 33
    • 0028072523 scopus 로고
    • DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2
    • Strasser, A., Harris, A.W., Jacks, T. & Cory, S. (1994) DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2. Cell, 79, 329-339.
    • (1994) Cell , vol.79 , pp. 329-339
    • Strasser, A.1    Harris, A.W.2    Jacks, T.3    Cory, S.4
  • 34
    • 0028097822 scopus 로고
    • Purification and characterization of the Fas-ligand that induces apoptosis
    • Suda, T. & Nagata, S. (1994) Purification and characterization of the Fas-ligand that induces apoptosis. Journal of Experimental Medicine, 179, 873-879.
    • (1994) Journal of Experimental Medicine , vol.179 , pp. 873-879
    • Suda, T.1    Nagata, S.2
  • 35
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson, C.B. (1995) Apoptosis in the pathogenesis and treatment of disease, Science, 267, 1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 37
    • 0024596722 scopus 로고
    • A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor
    • Yonehara, S., Ishii, A. & Yonehara, M. (1989) A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. Journal of Experimental Medicine, 169, 1747-1756.
    • (1989) Journal of Experimental Medicine , vol.169 , pp. 1747-1756
    • Yonehara, S.1    Ishii, A.2    Yonehara, M.3
  • 38
    • 0029059073 scopus 로고
    • The treatment of severe acquired aplastic anemia
    • Young, N.S. & Barret, A.J. (1995) The treatment of severe acquired aplastic anemia. Blood, 85, 3367-3377.
    • (1995) Blood , vol.85 , pp. 3367-3377
    • Young, N.S.1    Barret, A.J.2


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