Comparison of immunohistochemical staining of the novel antibody melan- A with S100 protein and HMB-45 in malignant melanoma and melanoma variants

Histopathology

Volumn 32, Issue 2, 1998, Pages 139-146

  Blessing, K ^a   Sanders, D S A ^b   Grant, J J H ^a  

^a WORTHING HOSPITAL   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Desmoplastic melanoma; HMB 45; Malignant melanoma; Melan A; Metastatic melanoma; Naevoid melanoma; S100 protein

Indexed keywords

PROTEIN S 100;

ANTIBODY DETECTION; ANTIBODY SPECIFICITY; ARTICLE; CANCER CLASSIFICATION; DIAGNOSTIC VALUE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MELANOMA; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; HUMANS; IMMUNOHISTOCHEMISTRY; MELANOMA; NEOPLASM PROTEINS; STAINING AND LABELING;

EID: 0031881252     PISSN: 03090167     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2559.1998.00312.x     Document Type: Article

References (18)

1. Moore BW. A soluble protein characteristic of the nervous system. Biochem. Biophys. Res. Commun. 1965: 19; 739-744.
2. Vanstapel MJ, Gatter KC, Wolf-Peeters C, Mason DY, Desmet VD. New site of human S100 immunoreactivity detected with monoclonal antibodies. Am. J. Clin. Pathol. 1986: 85; 160-168.
3. Takahashi K, Isobe T, Ohtsuki Y, Akagi T, Sonobe H, Okuyama T. Immunohistochemical study on the distribution of alpha and beta subunits of S100 protein in human neoplasms and normal tissues. Virchows Arch. (B) 1984: 45; 385-396.
4. Gown AM, Vogel AM, Hoak DH, Gough F, McNutt MA. Monoclonal antibodies specific for melanocytic tumours distinguish subpopulations of melanocyte. Am. J. Pathol. 1986: 123; 195-203.
5. Palazzo J, Duray DH. Typical, dysplastic, congenital and Spitz naevus: a comparative immunohistochemical study. Human Pathol. 1989: 20; 341-346.
6. Smoller BR, Mc Nutt NS, Hsu A. HMB-45 recognises stimulated melanocytes. J. Cutan. Pathol. 1989: 16; 49-53.
7. Sun J, Morton TH, Gown AM. Antibody HMB-45 identifies the cells of blue naevi. An immunohistichemical study on paraffin sections. Am. J. Surg. Pathol. 1990: 14; 748-755.
8. Skelton HG, Smith KJ, Barrett TL, Lupton GP, Graham JH. HMB-45 staining in benign and malignant melanocytic lesions. A reflection of cellular activation. Am. J. Dermatopathol. 1991: 13; 543-550.
9. Chen YT, Stockert E, Jungbluth A et al. Serological analysis of Melan-A (MART-1), a melanocyte-specific protein homogeneously expressed in human melanomas. Poc. Natl. Acad. Sci. 1996: 93; 5915-5919.
10. Jager E, Ringoffer M, Karbach J, Arand M, Oesch F, Knuth A. Inverse relationship of melanocyte differentiation antigen expression in melanoma tissues and CD8+ cytotoxic T cell responses: evidence for immunoselection of antigen loss variants in vivo. Int. J. Cancer 1996: 66; 470-476.
11. Norton AJ, Jordan S, Yeomans P. Brief high-temperature heat denaturation (pressure cooking): a simple and effective method of antigen retrieval for routinely processed tissues. J. Pathol. 1994: 173; 371-379.
12. Shi S-R, Key ME, Kalra KL. Antigen retrieval in formalin fixed, paraffin embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. J. Histochem. Cytochem. 1991: 39; 741-747.
13. Wong TY, Suster S, Duncan LM, Mihm MC. Naevoid melanoma: A clinicopathological study of seven cases of malignant melanoma mimicking spindle and epithelioid naevi and verrucous dermal naevus. Human Pathol. 1995: 26; 171-179.
14. Conley J, Lattes R, Orr W. Desmoplastic malignant melanoma (a rare variant of spindle cell melanoma). Cancer 1971: 28; 914-936.
15. Longacre TA, Egbert BM, Rouse RV. Desmoplastic and spindle cell melanoma. An immunohistochemical study. Am. J. Surg. Pathol. 1996: 20; 1489-1500.
16. Williams JH, Mepham BL, Wright DH. Tissue preparation for immunohistochemistry. J. Clin. Pathol. 1997: 50; 422-428.
17. Wick MR, Swanson PE, Rocamora A. Recognition of malignant melanoma by monoclonal antibody HMB-45: and immunohistochemical study of 200 paraffin embedded cutaneous tumours. J. Cutan. Pathol. 1988: 15; 201-207.
18. Evans MA, Evans AT, King G, Blessing K. Histopathological and immunohistochemical discrimination of pre-existing naevus from malignant melanoma. J. Pathol. 1996: 17s;43a.