Sequence analysis of a variety of primate fertilin α genes: Evidence for non-functional genes in the gorilla and man

Molecular Reproduction and Development

Volumn 51, Issue 1, 1998, Pages 92-97

  Jury, Jennifer A ^a   Frayne, Jan ^a   Hall, Len ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Disintegrin; Fertilization; Gene expression; Primate; Sperm antigens

Indexed keywords

FERTILIN; SPERM ANTIGEN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; FERTILIZATION; GENE EXPRESSION; GORILLA; HUMAN; MALE; MEMBRANE FUSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SPERM; ZONA PELLUCIDA;

ADAM PROTEINS; AMINO ACID SEQUENCE; ANIMALS; GORILLA GORILLA; HUMANS; MEMBRANE GLYCOPROTEINS; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; PRIMATES;

EID: 0031877099     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2795(199809)51:1<92::AID-MRD11>3.0.CO;2-W     Document Type: Article

References (16)

1. Almeida EAC, Huovilla APJ, Sutherland AE, Stephens LE, Calarco PG, Shaw LM, Mercurio AM, Sonnenberg A, Primakoff P, Myles DG, White JM (1995): Mouse egg integrin α6β1 functions as a sperm receptor. Cell 81:1095-1104.
2. Blobel CP, Wolfsberg TG, Turck CW, Myles DG, Primakoff, White, JM (1992): A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion. Nature 356:248-252.
3. Dracopoli NC, Haines JL, Korf BR, Moir DT, Morton CC, Seidman CE, Seidman JG, Smith DR (1994): Molecular analysis of paternity. Preparation of genomic DNA from whole blood. "Current Protocols in Human Genetics," vol. 2. John Wiley & Sons, pp 14.4.10-14.4.12
4. Evans JP, Schultz RM, Kopf GS (1995): Mouse sperm-egg plasma membrane interactions: Analysis of roles of egg integrins and the mouse sperm homologue of PH 30 (fertilin) β. J Cell Sci 108:3267-3278.
5. Evans JP, Kopf GS, Schultz RM (1997): Characterisation of the binding of recombinant mouse sperm fertilin β subunit to mouse eggs: Evidence for adhesive activity via an egg β1 integrin-mediated interaction. Dev Biol 187:79-93.
6. Frayne J, Jury JA, Barker HL, Hall L (1997): Rat MDC family of proteins: Sequence analysis, tissue distribution, and expression in prepubertal and adult rat testes. Mol Reprod Dev 48:159-167.
7. Hardy CM, Holland MK (1996): Cloning and expression of recombinant rabbit fertilin. Mol Reprod Dev 45:107-116.
8. Jury JA, Frayne J, Hall L (1997): The human fertilin α gene is non-functional: Implications for its proposed role in fertilization. Biochem J 321:577-581.
9. McLaughlin EA, Frayne J, Barker HL, Jury J, Jones R, Ford WCL, Hall L (1997): Cloning and sequence analysis of rat fertilin α and β - developmental expression, processing, and immunolocalisation. Mol Hum Reprod 3:801-809.
10. Myles DG, Kimmel LH, Blobel CP, White JM, Primakoff P (1994): Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion. Proc Natl Acad Sci USA 91:4195-4198
11. Perry ACF, Gichuhi PM, Jones R, Hall L (1995a): Cloning and analysis of monkey fertilin reveals novel α subunit isoforms. Biochem J 307:843-850.
12. Perry ACF, Jones R, Hall L (1995b): Analysis of transcripts encoding novel members of the mammalian metalloprotease-like, disintegrin-like, cysteine-rich (MDC) protein family and their expresion in reproductive and non-reproductive monkey tissues. Biochem J 312:239-244.
13. Primakoff P, Hyatt H, Tredick-Kline J (1987): Identification and purification of a sperm surface protein with a potential role in sperm-egg membrane fusion. J Cell Biol 104:141-149
14. Shalgi R, Matityahu A, Gaunt SJ, Jones R (1990): Identification of antigens on rat spermatozoa with a potential role in fertilization. Mol Reprod Dev 25:286-296.
15. Snell WJ, White, JM (1996): The molecules of mammalian fertilisation. Cell 85:629-637.
16. Wolfsberg TG, Straight PD, Gerena RL, Huovila A-PJ, Primakoff P, Myles DG, White JM (1995b): ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with a disintegrin and metalloprotease domain. Dev Biol 169:378-383.