Clinical implication of protein levels of IL-5 in induced sputum in asthmatic patients

Journal of Asthma

Volumn 35, Issue 3, 1998, Pages 243-249

  Shoji, Seiichi ^a   Kanazawa, Hiroshi ^a   Hirata, Kazuto ^a   Kurihara, Naotsugu ^a   Yoshikawa, Junichi ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Bronchial asthma; Eosinophil cationic protein; IL 5; Induced sputum

Indexed keywords

EOSINOPHIL CATIONIC PROTEIN; INTERLEUKIN 5;

ADULT; ALLERGIC ASTHMA; ARTICLE; ASTHMA; CELL COUNT; CLINICAL ARTICLE; CONTROLLED STUDY; EOSINOPHIL; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; HUMAN TISSUE; INFLAMMATION; MALE; PROTEIN CONTENT; SPUTUM;

EID: 0031875689     PISSN: 02770903     EISSN: None     Source Type: Journal    
DOI: 10.3109/02770909809068214     Document Type: Article

References (19)

1. Gibson PG, Girgis-Gabardo A, Morris MM, Mattoli S, Kay JM, Dolovich J, Denburg J, Hargreave FE: Cellular characteristics of sputum from patients with asthma and chronic bronchitis. Thorax 44:693 (1989).
2. Pin I, Gibson PG, Kolendowicz R, Girgis-Gabardo A, Denburg J, Hargreave FE, Dolovich J: Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 47:25 (1992).
3. Fahy JV, Liu J, Wong H, Boushey HA: Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis 147:1126 (1993).
4. Virchow JC, Jr., Holscher UWE, Virchow C, Sr.: Sputum ECP levels correlate with parameters of airflow obstruction. Am Rev Respir Dis 146:604 (1992).
5. Konno S, Gonokami Y, Kurokawa M, Kawazu K, Asano K, Okamoto K, Adachi M: Cytokine concentrations in sputum of asthmatic patients, Int Arch Allergy Immunol 109:73 (1996).
6. Pizzichini E, Pizzichini MMM, Efthimiadis A, Evans S, Morris MM, Squillace D, Gleich GJ, Dolovich J, Hargreave FE: Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements. Am J Respir Crit Care Med 154:308 (1996).
7. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Medical Section of The American Lung Association. Am Rev Respir Dis 136:225 (1987).
8. Makino S, Kobayashi S, Miyamoto T, Shida T, Takahashi S, Kabe J, et al: Standard for allergen bronchial provocation test in asthma and hypersensitive pneumonitis. Jpn J Allergol 31:1074 (1982).
9. Hansel TT, Braunstein JB, Walker C, Blaser K, Bruijnzeel PLB, Virchow JC, Jr., Virchow C, Sr.: Sputum eosinophils from asthmatics express ICAM-1 and HLA-DR. Clin Exp Immunol 86:271 (1991).
10. Sedgwick JB, Calhoun WJ, Gleich GJ, Kira H, Abrams JS, Schwartz LB, Volovitz B, Ben-Yaakov M, Busse WW: Immediate and late airway response of allergic rhinitis patients to segmental antigen challenge. Am Rev Respir Dis 144:1274 (1991).
11. Sur S, Gleich GJ, Swanson MC, Bartemes KR, Broide DH: Eosinophilic inflammation is associated with elevation of interleukin-5 in the airways of patients with spontaneous symptomatic asthma. J Allergy Clin Immunol 96:661 (1995).
12. Venge J, Lampinen M, Hakansson L, Rak S, Venge P: Identification of IL-5 and RANTES as the major eosinophilic chemoattractants in the asthmatic lung. J Allergy Clin Immunol 97:1110 (1996).
13. Sur S, Kita H, Gleich GJ, Chenier TC, Hunt LW: Eosinophil recruitment is associated with IL-5, but not with RANTES, twenty-four hours after allergen challenge. J Allergy Clin Immunol 97:1272 (1996).
14. Adachi T, Motojima S, Hirata A, Fukuda T, Makino S: Eosinophil viability-enhancing activity in sputum from patients with bronchial asthma: Contributions of interleukin-5 and granulocyte-macrophage colony-stimulating factor. Am J Respir Crit Care Med 152:618 (1995).
15. Saetta M, Di Stefano A, Maestrelli P, Turato G, Mapp CE, Pieno M, Zanguochi G, Del Prete G, Fabbri LM: Airway eosinophilia and expression of interleukin-5 protein in asthma and in exacerbations of chronic bronchitis, Clin Exp Allergy 26:766 (1996).
16. Humbert M, Durham RS, Sun Y, Kimmit P, Barkans J, Assoufi B, Pfister R, Menz G, Robinson SD, Kay AB, Corrigan CJ: IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma. Am J Respir Crit Care Med 154:1497 (1996).
17. Nocker RET, Schoonbrood DFM, Van de Graaf EA, Erik Hack C, Lutter R, Jansen HM, Out TA: Interleukin-8 in airway inflammation in patients with asthma and chronic obstructive pulmonary disease. Int Arch Allergy Immunol 109:183 (1996).
18. Kanazawa H, Kurihara N, Otsuka T, Fujii T, Tanaka S, Kudoh S, Hirata K, Takeda T: Clinical significance of serum concentration of Interleukin-8 in patients with asthma or chronic pulmonary emphysema. Respiration 63:236 (1996).
19. Fahy JV, Kim KW, Liu J, Boushey HA: Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation. J Allergy Clin Immunol 95:843 (1995).