Recombinant α-chains of type IV collagen demonstrate that the amino terminal of the Goodpasture autoantigen is crucial for antibody recognition

Clinical and Experimental Immunology

Volumn 113, Issue 1, 1998, Pages 17-27

  Ryan, J J ^a   Mason, P J ^b   Pusey, C D ^a   Turner, N ^c  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Autoantibody binding; B cell epitope; Glomerular basement membrane; Goodpasture antigen; Type IV collagen

Indexed keywords

AUTOANTIGEN; CHIMERIC PROTEIN; COLLAGEN TYPE 4; EPITOPE; GLOMERULUS BASEMENT MEMBRANE ANTIBODY; SULFUR 35;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; GLOMERULONEPHRITIS; GLOMERULUS BASEMENT MEMBRANE; GOODPASTURE SYNDROME; HUMAN; HUMAN TISSUE; LUNG HEMORRHAGE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-GLOMERULAR BASEMENT MEMBRANE DISEASE; ANTIBODY SPECIFICITY; AUTOANTIBODIES; AUTOANTIGENS; CLONING, MOLECULAR; COLLAGEN; COLLAGEN TYPE IV; COS CELLS; EPITOPES, B-LYMPHOCYTE; HUMANS; RATS; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031873470     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1998.00623.x     Document Type: Article

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