Sera from patients with anti-GBM nephritis including Goodpasture syndrome show heterogenous reactivity to recombinant NC1 domain of type IV collagen α chains

Nephrology Dialysis Transplantation

Volumn 11, Issue 11, 1996, Pages 2215-2222

  Dehan, P ^a,b   Weber, M ^c   Zhang, Xu ^a   Reeders, S T ^d   Foidart, J M ^b   Tryggvason, K ^a,e  

^a UNIVERSITY OF OULU   (Finland)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Anti GBM nephritis; Basement membrane; Goodpasture syndrome; IV collagen

Indexed keywords

AUTOANTIBODY; COLLAGEN TYPE 4; GLOMERULUS BASEMENT MEMBRANE ANTIBODY; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN;

ADULT; AGED; ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLOMERULONEPHRITIS; GLOMERULUS BASEMENT MEMBRANE; GOODPASTURE SYNDROME; HUMAN; IMMUNOBLOTTING; LUNG HEMORRHAGE; MALE; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN DOMAIN; RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS;

EID: 0029987544     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.ndt.a027139     Document Type: Article

References (30)

1. Wilson CB, Dixon FJ. The renal response to immunological injury. In: Berner BM, Rector FC, eds. The Kidney 3rd ed. Saunders, Philadelphia: 1986: 800-889
2. Lerner LA, Glassock RJ, Dixon FJ. The role of anti-glomerular basement membrane antibody in the pathogenesis of human glomerulonephritis. J Exp Med 1977; 126: 989-1004
3. Butkowski RJ, Langeveld JPM, Wieslander J, Hamilton J, Hudson BG. Localization of the Goodpasture epitope to a novel chain of basement membrane collagen. J Biol Chem 1987; 262: 7874-7877
4. Saus J, Wieslander J, Langeveld J, Quinones S, Hudson BG: Identification of the Goodpasture antigen as the α3(IV) chain of collagen IV. J Biol Chem 1988; 263: 13374-13380
5. Neilson EG, Kalluri R, Sun MJ et al. Specificity of Goodpasture autoantibodies for the recombinant noncollagenous domains of human type IV collagen. J Biol Chem 1993; 268: 8402-8405
6. Pusey CD, Dash A, Kershaw et al. A single autoantigen in Goodpasture's syndrome identified by a monoclonal antibody to human glomerular basement membrane. Lab Invest 1987; 56: 23-31
7. Hudson BG, Reeders ST, Tryggvason K. Type IV collagen: structure, gene organization, and role in human diseases: molecular basis of Goodpasture and Alport syndromes and diffuse leiomyomatosis. J Biol Chem 1993; 268: 26033-26036
8. Brazel D, Oberbäumer I, Dieringer H et al. Completion of the amino acid sequence of the α1 chain of human basement membrane collagen (type IV) reveals 21 non-triplet interruptions located within the collagenous domain. Eur J Biochem 1987; 168: 529-536
9. Soininen R, Haka-Risku T, Prockop DJ, Tryggvason K. Complete primary structure of the α1 chain of human basement membrane (type IV) collagen. FEBS Lett 1987; 225: 188-194
10. Hostikka SL, Tryggvason K. The complete primary structure of the α2 chain of human type IV collagen and comparison with the α1(IV) chain. J Biol Chem 1988; 263: 19488-19493
11. Mariyama M, Leinonen A, Mochizuki T, Tryggvason K, Reeders S. Complete primary structure of the human α3(IV) collagen chain: coexpression of the α3(IV) and α4(IV) collagen chains in human tissues. J Biol Chem 1994; 269: 23013-23017
12. Leinonen A, Mariyama M, Mochizuki T, Tryggvason K, Reeders S. Complete primary structure of the human type IV collagen α4(IV) chain: Comparison with structure and expression of the other α(IV) chains. J Biol Chem 1994; 269: 26172-26177
13. Zhou J, Ding M, Zhao Z, Reeders ST. Complete primary structure of the sixth chain of human basement membrane collagen, α6(IV). Isolation of the cDNAs for α6(IV) and comparison with five other type IV collagen chains. J Biol Chem 1994; 269: 13193-13199
14. Oohashi T, Sugimoto M, Mattei MG, Ninomiya Y. Identification of a new collagen IV chain, α6(IV), by cDNA isolation and assignment of the gene to chromosome Xq22, which is the same locus for COL4A5. J Biol Chem 1994; 269: 7520-7526
15. Butkowski RJ, Wieslander J, Kleppel M, Michael AF, Fish AJ. Basement membrane collagen in the kidney: regional localization of novel chains related to collagen IV. Kidney Int 1989; 35: 1195-1200
16. Kleppel MM, Kashtan C, Santi PA, Wieslander J, Michael AF. Distribution of familial nephritis antigen in normal tissue and renal basement membranes of patients with homozygous and heterozygous Alport familial nephritis. Relationship of familial nephritis and Goodpasture antigens to novel collagen chains and type IV collagen. Lab Invest 1989: 61: 278-289
17. Sanes JR, Engvall E, Butkowski R, Hunter DD. Molecular heterogeneity of basal laminae: isoforms of laminin and collagen IV at the neuromuscular junction and elsewhere. J Biol Chem 1990; 111: 1685-1699
18. Yaar M, Foidart JM, Brown KS, Rennard SI, Martin GR, Liotta L. The Goodpasture-like syndrome in mice induced by intravenous injections of anti-type IV collagen and anti-laminin antibody. Am J Pathol 1982; 107: 79-91
19. Zimmerman SW, Varnasi UR, Hoff B Goodpasture's syndrome with normal renal function. Am J Med 1979; 66: 163-170
20. Weber M, Pullig O. Different immunologic properties of the globular NC1 domain of collagen type IV isolated from various human basement membranes. Eur J Clin Invest 1992; 22: 138-146
21. Smith DB, Johnson KS Single-step purification of polypeptides expressed in Escherichia coli in fusion with glutathione-S-transferase. Gene 1988; 67: 31-40
22. Kalluri K, Gunwar S, Reeders S et al. Goodpasture syndrome. Localization of the epitope for the antibodies to the carboxy-terminal region of the α3(IV) chain of basement membrane collagen. J Biol Chem 1991; 266: 24018-24024
23. Yoshioka K, Kleppel M, Fish AJ. Analysis of nephritogenic antigens in human glomerular basement membrane by two-dimensional gel electrophoresis. J Immunol 1985; 134: 3831-3837
24. Derry CJ, Pickering M, Baker C, Pusey CD. Identification of the Goodpasture antigen, α4(IV) NC1, and four other NC1 domains of type IV collagen, by amino-terminal sequence analysis of human glomerular basement membrane separated by two-dimensional electrophoresis. Exp Nephrol 1994; 2: 249-256
25. Hellmark T, Johansson C, Wieslander J. Characterization of anti-GBM antibodies involved in Goodpasture's syndrome. Kidney Int 1994; 46: 823-828.
26. Kalluri R, Wilson CB, Weber M et al. Identificaton of the α3 chain of type IV collagen as the common autoantigen in antibasement membrane disease and Goodpasture syndrome. J Am Soc Nephrol 1995; 6: 1178-1185
27. Weber M, Meyer zum Büschenfelde K-H, Köhler H. Immunological properties of the human Goodpasture target antigen. Clin Exp Immunol 1988; 74: 289-294
28. Wilson CB, The renal response to immunological injury. In: Berner BM, Rector FC, eds. The Kidney 4th ed. Saunders, Philadelphia: 1991: 1095
29. Beirne GJ, Wagnild JP, Zimmerman SW, Macken PD, Burkholder PM. Idiopathic crescentic glomerulonephritis Medecine 1977; 56: 349-381
30. Ninomiya Y, Kagawa M, Iyama K et al. Differential expression of two basement membrane collagen genes, COL4A6 and COL4A5, demonstrated by immunofluorescence staining using peptide-specific monoclonal antibodies. J Cell Biol 1995; 130: 1219-1229