메뉴 건너뛰기




Volumn 54, Issue 2, 1998, Pages 435-444

Contribution of serine residues to constitutive and agonist- induced signaling via the D(2S) dopamine receptor: Evidence for multiple, agonist- specific active conformations

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; DIHYDREXIDINE; DOPAMINE 2 RECEPTOR STIMULATING AGENT; GUANINE NUCLEOTIDE BINDING PROTEIN; POTASSIUM CHANNEL;

EID: 0031871997     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.54.2.435     Document Type: Article
Times cited : (83)

References (38)
  • 1
    • 0009644628 scopus 로고
    • Some quantitative uses of drug antagonists
    • Arunlakshana O and Schild HO (1959) Some quantitative uses of drug antagonists. Br J Pharmacol 14:48-58.
    • (1959) Br J Pharmacol , vol.14 , pp. 48-58
    • Arunlakshana, O.1    Schild, H.O.2
  • 2
    • 0026729248 scopus 로고
    • Contributions of conserved serine residues to the interactions of ligands with dopamine D2 receptors
    • Cox BA, Henningsen RA, Spanoyannis A, Neve RL, and Neve KA (1992) Contributions of conserved serine residues to the interactions of ligands with dopamine D2 receptors. J Neurochem 59:627-635.
    • (1992) J Neurochem , vol.59 , pp. 627-635
    • Cox, B.A.1    Henningsen, R.A.2    Spanoyannis, A.3    Neve, R.L.4    Neve, K.A.5
  • 3
    • 0023505641 scopus 로고
    • The use of Xenopus oocytes for the study of ion channels
    • Dascal N (1987) The use of Xenopus oocytes for the study of ion channels. CRC Crit Rev Biochem 22:317-387.
    • (1987) CRC Crit Rev Biochem , vol.22 , pp. 317-387
    • Dascal, N.1
  • 5
    • 0027477778 scopus 로고
    • 2 dopamine receptor activation of a potassium channel in rat lactotrophs
    • 2 dopamine receptor activation of a potassium channel in rat lactotrophs. J Physiol 462:563-578.
    • (1993) J Physiol , vol.462 , pp. 563-578
    • Einhorn, L.C.1    Oxford, G.S.2
  • 6
    • 0029086487 scopus 로고
    • Molecular mechanisms of agonism: Agonists determine receptor conformation and hence G protein affinity
    • Gardner B (1995) Molecular mechanisms of agonism: agonists determine receptor conformation and hence G protein affinity. Trends Pharmacol Sci 16:259-260.
    • (1995) Trends Pharmacol Sci , vol.16 , pp. 259-260
    • Gardner, B.1
  • 7
    • 0025919746 scopus 로고
    • i protein subtypes regulate a single effector mechanism
    • i protein subtypes regulate a single effector mechanism. Mol Pharmacol 40:707-711.
    • (1994) Mol Pharmacol , vol.40 , pp. 707-711
    • Gerhardt, M.A.1    Neubig, R.R.2
  • 8
    • 0028856707 scopus 로고
    • 2 adrenergic receptor: Evidence for ligand-specific conformational changes
    • 2 adrenergic receptor: evidence for ligand-specific conformational changes. J Biol Chem 270:28268-28275.
    • (1995) J Biol Chem , vol.270 , pp. 28268-28275
    • Gether, U.1    Lin, S.S.2    Kobilka, B.K.3
  • 9
    • 0027950411 scopus 로고
    • Discrete activation of transduction pathways associated with acetylcholine m1 receptor by several muscarinic ligands
    • Gurwitz D, Haring R, Heldman E, Fraser CM, Manor D, and Fisher A (1994) Discrete activation of transduction pathways associated with acetylcholine m1 receptor by several muscarinic ligands. Eur J Pharmacol 267:21-31.
    • (1994) Eur J Pharmacol , vol.267 , pp. 21-31
    • Gurwitz, D.1    Haring, R.2    Heldman, E.3    Fraser, C.M.4    Manor, D.5    Fisher, A.6
  • 12
    • 0029866748 scopus 로고    scopus 로고
    • 1-adrenergic receptor agonist binding and activation
    • 1-adrenergic receptor agonist binding and activation. J Biol Chem 271:6322-6327.
    • (1996) J Biol Chem , vol.271 , pp. 6322-6327
    • Hwa, J.1    Perez, D.M.2
  • 13
    • 0029054965 scopus 로고
    • Agonist-receptor efficacy. II: Agonist trafficking of receptor signals
    • Kenakin T (1995) Agonist-receptor efficacy. II: Agonist trafficking of receptor signals. Trends Pharmacol Sci 16:232-238.
    • (1995) Trends Pharmacol Sci , vol.16 , pp. 232-238
    • Kenakin, T.1
  • 14
    • 0029812311 scopus 로고    scopus 로고
    • The classification of seven transmembrane receptors in recombinant expression systems
    • Kenakin T (1996) The classification of seven transmembrane receptors in recombinant expression systems. Pharmacol Rev 48:413-463.
    • (1996) Pharmacol Rev , vol.48 , pp. 413-463
    • Kenakin, T.1
  • 15
    • 0029048104 scopus 로고
    • + channels are activated by Gβγ subunits and function as heteromultimers
    • + channels are activated by Gβγ subunits and function as heteromultimers. Proc Natl Acad Sci USA 92:6542-6546.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6542-6546
    • Kofuji, P.1    Davidson, N.2    Lester, H.A.3
  • 18
    • 0030610845 scopus 로고    scopus 로고
    • s complex: Evidence for agonist-specific states
    • s complex: evidence for agonist-specific states. Mol Pharmacol 52:144-154.
    • (1997) Mol Pharmacol , vol.52 , pp. 144-154
    • Krumins, A.M.1    Barber, R.2
  • 20
    • 0027336835 scopus 로고
    • b from inhibition curves in functional experiments: Alternatives to the Cheng-Prusoff equation
    • b from inhibition curves in functional experiments: alternatives to the Cheng-Prusoff equation. Trends Pharmacol Sci 14:237-239.
    • (1993) Trends Pharmacol Sci , vol.14 , pp. 237-239
    • Lazareno, S.1    Birdsall, N.J.M.2
  • 25
    • 0030049488 scopus 로고    scopus 로고
    • Constitutive activation of a single effector pathway: Evidence for multiple activation states of a G protein-coupled receptor
    • Perez DM, Hwa J, Gaivin R, Mathur M, Brown F, and Graham RM (1996) Constitutive activation of a single effector pathway: evidence for multiple activation states of a G protein-coupled receptor. Mol Pharmacol 49:112-122.
    • (1996) Mol Pharmacol , vol.49 , pp. 112-122
    • Perez, D.M.1    Hwa, J.2    Gaivin, R.3    Mathur, M.4    Brown, F.5    Graham, R.M.6
  • 26
    • 0026630139 scopus 로고
    • Serine mutations in transmembrane V of the dopamine D1 receptor affect ligand interactions and receptor activation
    • Pollock NJ, Manelli AM, Hutchins CW, Steffey ME, MacKenzie RG, and Frail DE (1992) Serine mutations in transmembrane V of the dopamine D1 receptor affect ligand interactions and receptor activation. J Biol Chem 267:17780-17786.
    • (1992) J Biol Chem , vol.267 , pp. 17780-17786
    • Pollock, N.J.1    Manelli, A.M.2    Hutchins, C.W.3    Steffey, M.E.4    MacKenzie, R.G.5    Frail, D.E.6
  • 27
    • 0030839475 scopus 로고    scopus 로고
    • Agonist-specific coupling of a cloned Drosophila melanogaster D1-like dopamine receptor to multiple second messenger pathways by synthetic agonists
    • Reale V, Hannan F, Hall LM, and Evans PD (1997) Agonist-specific coupling of a cloned Drosophila melanogaster D1-like dopamine receptor to multiple second messenger pathways by synthetic agonists. J Neurosci 17:6545-6553.
    • (1997) J Neurosci , vol.17 , pp. 6545-6553
    • Reale, V.1    Hannan, F.2    Hall, L.M.3    Evans, P.D.4
  • 28
    • 0028348690 scopus 로고
    • Agonist-specific coupling of a cloned Drosophila octopamine/tyramine receptor to multiple second messenger systems
    • Robb S, Cheek TR, Hannan FL, Hall LM, Midgley JM, and Evans PD (1994) Agonist-specific coupling of a cloned Drosophila octopamine/tyramine receptor to multiple second messenger systems. EMBO J 13:1325-1330.
    • (1994) EMBO J , vol.13 , pp. 1325-1330
    • Robb, S.1    Cheek, T.R.2    Hannan, F.L.3    Hall, L.M.4    Midgley, J.M.5    Evans, P.D.6
  • 31
    • 0014625412 scopus 로고
    • A radioisotopic method for measuring the formation of adenosine 3′,5′-monophosphate in incubated slices of brain
    • Shimizu H, Daly JW, and Creveling CR (1969) A radioisotopic method for measuring the formation of adenosine 3′,5′-monophosphate in incubated slices of brain. J Neurochem 16:1609-1619.
    • (1969) J Neurochem , vol.16 , pp. 1609-1619
    • Shimizu, H.1    Daly, J.W.2    Creveling, C.R.3
  • 32
    • 0024344941 scopus 로고
    • Identification of two serine residues involved in agonist activation of the β-adrenergic receptor
    • Strader CD, Candelore MR, Hill WS, Sigal IS, and Dixon RAF (1989) Identification of two serine residues involved in agonist activation of the β-adrenergic receptor. J Biol Chem 264:13572-13578.
    • (1989) J Biol Chem , vol.264 , pp. 13572-13578
    • Strader, C.D.1    Candelore, M.R.2    Hill, W.S.3    Sigal, I.S.4    Dixon, R.A.F.5
  • 33
    • 0026006986 scopus 로고
    • 2A-adrenergic receptors: Identification of amino acids involved in ligand binding and receptor activation by agonists
    • 2A-adrenergic receptors: identification of amino acids involved in ligand binding and receptor activation by agonists. Mol Pharmacol 40:168-179.
    • (1991) Mol Pharmacol , vol.40 , pp. 168-179
    • Wang, C.-D.1    Buck, M.A.2    Fraser, C.M.3
  • 35
  • 38
    • 0021697164 scopus 로고
    • 2-dopamine receptor of the anterior pituitary gland
    • 2-dopamine receptor of the anterior pituitary gland. Mol Pharmacol 26:214-227.
    • (1984) Mol Pharmacol , vol.26 , pp. 214-227
    • Wreggett, K.A.1    De Léan, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.