Influence of the dosing frequency of parathyroid hormone-(1-38) on its anabolic effect in bone and on the balance of calcium, phosphorus and magnesium

Zeitschrift fur Ernahrungswissenschaft

Volumn 37, Issue 2, 1998, Pages 183-189

  Riond, J L ^a   Goliat von Fischer, I ^a   Kuffer B ^a   Toromanoff, A ^a   Forrer, R ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Balance; Calcium; Magnesium; Parathyroid hormone; Phosphate

Indexed keywords

CALCIUM ION; DNA; HYDROXYPROLINE; MAGNESIUM ION; PARATHYROID HORMONE; PARATHYROID HORMONE DERIVATIVE; PARATHYROID HORMONE[1-38]; PHOSPHORUS; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE TURNOVER; CALCIUM ABSORPTION; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; DOSE RESPONSE; ELECTROLYTE BALANCE; FEMALE; FEMUR; LUMBAR VERTEBRA; NONHUMAN; OSSIFICATION; OSTEOPOROSIS; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; BODY WEIGHT; BONE AND BONES; BONE DENSITY; BONE DEVELOPMENT; CALCIUM; FEMALE; HOMEOSTASIS; HUMANS; MAGNESIUM; PARATHYROID HORMONE; PEPTIDE FRAGMENTS; PHOSPHATES; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0031871618     PISSN: 0044264X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003940050015     Document Type: Article

References (40)

1. Canalis E, Centrella M, Burch W, McCarthy TL (1989) Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone culture. J Clin Invest 83:60-65
2. DeBartolo TF, Pegg LE, Shasserre C, Hahn TJ (1982) Comparison of parathyroid hormone and calcium ionophore A23187: effects on bone résorption and nucleic acid synthesis in cultured fetal rat bone. Calc Tissue Int 34:495-500
3. Dempster DW, Cosman F, Parisien M, Shen V, Lindsay R (1993) Anabolic action of parathyroid hormone on bone. Endocrine Rev 14:690-709
4. Ejersted C, Andreassen TT, Oxlund H, Jorgensen PH, Bak B, Häggblad J, Torring O, Nilsson MHL (1993) Human parathyroid hormone (1-34) and (1-84) increase the mechanical strength and thickness of cortical bone in rats. J Bone Min Res 9:1097-1101
5. Erben RG, Kohn B, Weiser H, Sinowatz F, Rambeck WA (1990) Role of vitamin D metabolites in the prevention of the osteopenia induced by ovariectomy in the axial and appendicular skeleton of the rat. Z Ernährungswiss 29:229-248
6. Erben RG, Weiser H, Sinowatz F, Rambeck WA, Zucker H (1992) Vitamin D metabolites prevent vertebral osteopenia in ovariectomized rats. Calcif Tissue Int 50:228-236
7. Farndale RW, Sandy JR, Atkinson SJ, Pennington SR, Meghji S, Meikle MC (1988) Parathyroid hormone and prostaglandin £2 stimulate both inositol phosphates and cyclic AMP accumulation in mouse osteoblast cultures. Biochem J 252:263-268
8. Gordeladze JO, Halse J, Djoseland O, Haugen HN (1978) A simple procedure for the determination of hydroxyproline in urine and bone. Biochem Med 20:23-30
9. Hock JM, Géra I (1992) Effects of continuous and intermittent administration and inhibition of résorption on the anabolic response of bone to parathyroid hormone. J Bone Min Res 7:65-72
10. Jerome CP (1994) Anabolic effect of high doses of human parathyroid hormone (1-38) in mature intact female rats. J Bone Min Res 9:933-942
11. Kimmel DB, Bozzato RP, Kronis KA, Coble T, Sindrey D, Kwong P, Recker RR (1993) The effect of recombinant human (1-84) or synthetic human (1-34) parathyroid hormone on the skeleton of adult osteopenic ovariectomized rats. Endocrinology 132: 1577-1584
12. Kream BE, Rowe DW, Gworek SC, Raisz LG (1980) Parathyroid hormone alters collagen synthesis and procollagen mRNA levels in fetal rat calvaria. Proc Natl Acad Sei USA 77:5654-5658
13. Labarca C, Paigen K (1980) A simple rapid and sensitive DNA assay procedure. Anal Biochem 102:344-352
14. Linkhart TA, Mohan S, Baylink DJ (1988) Bone repletion in vitro: Evidence for a locally regulated bone repair response to PTH treatment. Bone 9:371-379
15. MacDonald BR, Gallagher JA, Russell RGG (1986) Parathyroid hormone stimulates the proliferation of cells derived from human bone. Endocrinology 118:2445-2449
16. Margolis RN, Canalis E, Partridge NC (1996) Invited review of a workshop: Anabolic hormones in bone: Basic research and therapeutic potential. J Clin Endocrinol Metab 81:872-877
17. Meng XW, Liang XG, Birchman R, Wu DD, Dempster DW, Lindsay R, Shen V (1996) Temporal expression of the anabolic action of PTH in cancellous bone of ovariectomized rats. J Bone Min Res 11:421-429
18. Mosekilde L, Danielsen CC, Gasser J (1994) The effect on vertebral bone mass and strength of long term treat-ment with antiresorptive agents (estrogen and calcitonin), human parathyroid hormone-(l-38), and combination therapy, assessed in aged ovariectomized rats. Endocrinology 134:2126-2134
19. Mosekilde L, Danielsen CC, Sogaard CH, McOsker JE, Wronski TJ (1995) The anabolic effects of parathyroid hormone on cortical bone mass, dimensions and strength - assessed in a sexually mature, ovariectomized rat model. Bone 16:223-230
20. Mosekilde L, Sogaard CH, Danielsen CC, Torring O, Nilsson MHL (1991) The anabolic effects of human parathyroid hormone (hPTH) on rat vertebral body mass are also reflected in the quality of bone, assessed by biomechemical testing: A comparison study between hPTH-(l-34) and hPTH-(l-84). Endocrinology 129:421-428
21. Mosekilde L, Thomsen JS, McOsker JE (1997) No loss of biomechanical effects after withdrawal of short-term PTH treatment in an aged, osteopenic, ovariectomized rat model. Bone 20:429-437
22. Nishida S, Yamaguchi A, Tanizawa T, Endo N, Mashiba T, Uchiyama Y, Suda T, Yoshiki S, Takahashi HE (1994) Increased bone formation by intermittent parathyroid hormone administration is due to the stimulation of proliferation and differentiation of osteoprogenitor cells in bone marrow. Bone 15:711-723
23. Partridge NC, Bloch SR, Pearman AT (1994) Signal transduction pathways mediating parathyroid hormone regulation of osteoblastic gene expression. J Cel Biochem 55:321-327
24. Partridge NC, Opie AL, Opie RT, Martin TJ (1985) Inhibitory effect of parathyroid hormone on growth of osteogenic osteosarcoma cells. Calcif Tissue Int 37:519-525
25. Podbesek R, Edouard C, Meunier PJ, Parsons JA, Reeve J, Stevenson RW, Zanelli JM (1983) Effects of two treatment regimes with synthetic human pa-rathyroid hormone fragment on bone formation and the tissue balance of trabecular bone in Greyhounds. Endocrinology 112:1000-1006
26. Podbesek RD, Mawer EB, Zanelli GD, Parsons JA, Reeve J (1984) Intestinal absorption of calcium in greyhounds: the response to intermittent and continuous administration of human synthetic parathyroid hormone fragment 1-34 (hPTH 1-34). Clin Sei 67:591-599
27. Qi H, Li M, Wronski TJ (1995) A comparison of the anabolic effects of parathyroid hormone at skeletal sites with moderate and severe osteopenia in aged ovariectomized rats. J Bone Min Res 10:948-955
28. Reeve J, Bradbeer JN, Arlot M, Davies UM, Green JR, Hampton L, Edouard C, Hesp R, Hulme P, Ashby JP, Zanelli JM, Meunier PJ (1991) hPTH 1-34 treatment of osteoporosis with added hormone replacement therapy: Biochemical, kinetic and histological responses. Osteoporosis Int 1:162-170
29. Riond JL (1993) Modulation of the anabolic effect of synthetic human parathyroid hormone fragment-(l-34) in the bone of growing rats by variations in the dosage regimen. Clin Sei 85:223-228
30. Sabatini M, Lesur C, Fâcherie M, Pastoureau P, Kucharczyk N, Fauchère JL, Bonnet J (1996) Effects of parathyroid hormone and agonists of the adenylyl cyclase and protein kinase C pathways on bone cell proliferation. Bone 18:59-65
31. Suki WN, Rouse D (1996) Renal transport of calcium, magnesium and phosphate. In: Brenner BM (ed) The Kidney, 5lh ed.; WB Saunders Comp, Philadelphia, pp 472-508
32. Tarn CS, Heersche JNM, Murray TM, Parsons JA (1982) Parathyroid hormone stimulates the bone apposition rate independently of its resorptive action: differential effects of intermittent and continuous administration. Endocrinology 110:506-512
33. Toromanoff A, Amman P, Mosekilde L, Thomsen JS, Riond JL (1997) Parathyroid hormone increases bone formation and improves mineral balance in vitamin D-deficient female rats. Endocrinology 138:2449-2457
34. Toromanoff A, Amman P, Riond JL (1998) Early effects of short-term parathyroid hormone administration on bone mass, mineral content and strength in female rats. Bone 22:217223
35. Uzawa T, Hori M, Ejiri S, Ozawa H (1995) Comparison of the effects of intermittent and continuous administration of human parathyroid hormone (1-34) on rat bone. Bone 16:477-484
36. Van der Plas A, Feyen JHM, Nijweide PJ (1985) Direct effect of parathyroid hormone on the proliferation of osteoblast-like cells: A possible role of cyclic AMP. Biochem Biophys Res Comm 129:918-925
37. Vargas SJ, Raisz LG (1990) Simultaneous assessment of bone résorption and formation in cultures of 22-day fetal rat parietal bones: effects of parathyroid hormone and prostaglandin E2. Bone 11:61-65
38. Wronski TJ, Yen CF (1994) Anabolic effects of parathyroid hormone on cortical bone in ovariectomized rats. Bone 15:51-58
39. Whitfield JF, Morley P (1995) Small bone-building fragments of parathyroid hormone: new therapeutic agents for osteoporosis. Trends Pharmacol Sei 16:382-386
40. Whitfield JF, Morley P, Willick GE, Ross V, MacLean S, Barbier JR, Isaacs RJ, Ohannessian-Barry L (1997) Comparison of the ability of recombinant human parathyroid hormone, rhPTH(1-84), and hPTH-(l-31)NH2 to stimulate femoral trabecular bone growth in ovariectomized rats. Calcif Tissue Int 60:26-29