Comparative 5-HT4 receptor antagonist activity of LY353433 and its active hydroxylated metabolites

Drug Development Research

Volumn 43, Issue 4, 1998, Pages 193-199

  Cohen, Marlene L ^a   Bloomquist, William ^a   Calligaro, David ^a   Swanson, Steven ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

5 HT4 receptor antagonist; Ex vivo rat studies; LY353433 metabolites; Pharmacokinetics; Rat esophagus

Indexed keywords

DRUG METABOLITE; LY 353433 MALEATE; SEROTONIN 4 ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DISSOCIATION CONSTANT; ESOPHAGUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PLASMA; RAT; RECEPTOR AFFINITY;

EID: 0031870681     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199804)43:4<193::AID-DDR2>3.0.CO;2-D     Document Type: Article

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