Cis-acting elements are required for selenium regulation of glutathione peroxidase-1 mRNA levels

RNA

Volumn 4, Issue 7, 1998, Pages 816-827

  Weiss, Sherri L ^a   Sunde, Roger A ^a  

^a UNIVERSITY OF MISSOURI   (United States)

Author keywords

globin; Intron; Mammalian cells; mRNA stability; Nonsense codon; Phospholipid hydroperoxide glutathione peroxidase; Selenocysteine insertion element; Translation

Indexed keywords

BETA GLOBIN; GLUTATHIONE PEROXIDASE; HYDROPEROXIDE; MESSENGER RNA; PHOSPHOLIPID; SELENIUM; SELENOCYSTEINE;

ANIMAL CELL; ARTICLE; CHO CELL; CODON; ENZYME REGULATION; GENE EXPRESSION REGULATION; GENE INSERTION; GLUTATHIONE METABOLISM; NONHUMAN; NONSENSE MUTATION; PRIORITY JOURNAL; RNA ANALYSIS;

ANIMALS; CHO CELLS; CRICETINAE; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLOBINS; GLUTATHIONE PEROXIDASE; MICE; RECOMBINANT FUSION PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; RNA, MESSENGER; SELENIUM; TRANSFECTION;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; MAMMALIA;

EID: 0031870674     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838298971990     Document Type: Article

References (49)

1. Ahern SM, Miyata T, Sadler JE. 1993. Regulation of human tissue factor expression by mRNA turnover. J Biol Chem 260:2154-2159.
2. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K. 1989. Current protocols in molecular biology. New York: Wiley & Sons.
3. Belgrader P, Cheng J, Maquat LE. 1993. Evidence to implicate translation by ribosomes in the mechanism by which nonsense codons reduce the nuclear level of human triosephosphate isomerase mRNA. Proc Natl Acad Sci USA 90:482-486.
4. Bermano G, Arthur JR, Hesketh JE. 1996a. Role of the 3′ untranslated region in the regulation of cytosolic glutathione peroxidase and phospholipid-hydroperoxide glutathione peroxidase gene expression by selenium supply. Biochem J 320:891-895.
5. Bermano G, Nicol F, Dyer JA, Sunde RA, Beckett GJ, Arthur JR, Hesketh JE. 1996b. Selenoprotein gene expression during selenium-repletion of selenium-deficient rats. Biol Tr Elem Res 51:211-223.
6. Berry MJ, Banu L, Chen Y, Mandel SJ, Kieffer JD, Harney JW, Larsen PR. 1991. Recognition of a UGA as a selenocysteine codon in type 1 deiodinase requires sequences in the 3′ untranslated region. Nature (Lond) 353:273-276.
7. Berry MJ, Banu L, Harney JW, Larsen PR. 1993. Functional characterization of the eukaryotic SECIS elements which direct seleno-cysteine insertion at UGA codons. EMBO J 12:3315-3322.
8. Binder R, Horowitz JA, Basilion JP, Koeller DM, Klausner RD, Harford JB. 1994. Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3′ UTR and does not involve poly(A) tail shortening. EMBO J 13:1969-1980.
9. Carter MS, Li S, Wilkinson MF. 1996. A splicing-dependent regulatory mechanism that detects translation signals. EMBO J 15(21):5965-5975.
10. Casey JL, Koeller DM, Ramin VC, Klausner RD, Harford JB. 1989. Iron regulation of transferrin receptor mRNA levels requires iron-responsive elements and a rapid turnover determinant in the 3′ untranslated region of the mRNA. EMBO J 8:3693-3699.
11. Chambers I, Frampton J, Goldfarb P, Affara N, McBain W, Harrison PR. 1986. The structure of the mouse glutathione peroxidase gene: The selenocysteine in the active site is encoded by the "termination" codon, TGA. EMBO J 5:1221-1227.
12. Cheng J, Belgrader P, Zhou X, Maquat LE. 1994. Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance. Mol Cell Biol 14:6317-6325.
13. Cheng J, Maquat LE. 1993. Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA. Mol Cell Biol 13:1892-1902.
14. Christensen MJ, Burgener KW. 1992. Dietary selenium stabilizes glutathione peroxidase messenger RNA in rat liver. J Nutr 122:1620-1626.
15. DePalo D, Kinlaw WB, Zhao C, Engelberg-Kulka H, St Germain DL 1994. Effect of selenium deficiency on type I 5′-deiodinase. J Biol Chem 269(23):16223-16228.
16. Hafeman DG, Sunde RA, Hoekstra WG. 1974. Effect of dietary selenium on erythrocyte and liver glutathione peroxidase in the rat. J Nutr 104:580-587.
17. Haile DJ, Rouault TA, Tag CK, Chin J, Harford JB, Klausner RD. 1992. Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: Role of the iron-sulfur cluster. Proc Natl Acad Sci USA 89:7536-7540. Hatfield D, Diamond A, Dudock B. 1982. Opal suppressor serine tRNA from bovine liver form phosphoseryl-tRNA. Proc Natl Acad Sci USA 79:6215-6219.
18. Haile DJ, Rouault TA, Tag CK, Chin J, Harford JB, Klausner RD. 1992. Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: Role of the iron-sulfur cluster. Proc Natl Acad Sci USA 89:7536-7540. Hatfield D, Diamond A, Dudock B. 1982. Opal suppressor serine tRNA from bovine liver form phosphoseryl-tRNA. Proc Natl Acad Sci USA 79:6215-6219.
19. Hill KE, Lyons PR, Burk RF. 1992. Differential regulation of rat liver selenoprotein mRNAs in selenium deficiency. Biochem Biophys Res Commun 185:260-263.
20. Ho Y, Howard AJ, Crapo JD. 1988. Nucleotide sequence of a rat glutathione peroxidase cDNA. Nucleic Acids Res 16:5207.
21. Jacobson A, Peltz SW. 1996. Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells. Annu Rev Biochem 65:693-739.
22. Kaptain S, Downey WE, Tang CC, Philpott C, Haile DJ, Orloff DG, Harford JB, Rouault TA, Klausner RD. 1991. A regulated RNA binding protein also possesses aconitase activity. Proc Natl Acad Sci USA 88:10109-10113.
23. Knudsen S, Brunak S. 1997. Kissing loops hide premature termination codons in pre-mRNA of selenoprotein genes and in genes containing programmed ribosomal frameshifts. RNA 3:697-701.
24. Kunkel TA. 1985. Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc Natl Acad Sci USA 82:488-492.
25. Lawrence RA, Sunde RA, Schwartz GL, Hoekstra WG. 1974. Glutathione peroxidase activity in rat lens and other tissues in relation to dietary selenium intake. Exp Eye Res 18:563-569.
26. Lei XG, Evenson JK, Thompson KM, Sunde RA. 1995. Glutathione peroxidase and phospholipid hydroperoxide glutathione peroxidase are differentially regulated in rats by dietary selenium. J Nutr 125:1438-1446.
27. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275.
28. Maquat LE. 1995. When cells stop making sense: Effects of nonsense codons on RNA metabolism in vertebrate cells. RNA 1:453-465.
29. Martin GW III, Harney JW, Berry MJ. 1996. Selenocysteine incorporation in eukaryotes: Insights into mechanism and efficiency from sequence, structure, and spacing proximity studies of the type 1 deiodinase SECIS element. RNA 2:171-182.
30. McKown DM, Morris JS. 1978. Rapid measurement of selenium in biological samples using instrumental neutron activation analysis. J Radioanal Chem 43:411-420.
31. Moskow JA, Morrow CS, He R, Mullenbach GT, Cowan KH. 1992. Structure and function of the 5′-flanking sequence of the human cytosolic selenium-dependent glutathione peroxidase gene (hgpx1). J Biol Chem 267:5949-5958.
32. Pushpa-Rekha TR, Burdsall AL, Oleksa LM, Chisolm GM, Driscoll DM. 1995. Rat phospholipid-hydroperoxide glutathione peroxidase: cDNA cloning and identification of multiple transcription and translation start sites. J Biol Chem 270:26993-26999.
33. Rhoads DD, Roufa DJ. 1985. Emetine resistance of Chinese hamster cells: Structures of wild-type and mutant ribosomal protein S14 mRNAs. Mol Cell Biol 5:1655-1659.
34. Saedi MS, Smith CG, Frampton J, Chambers I, Harrison PR, Sunde RA. 1988. Effect of selenium status on mRNA levels for glutathione peroxidase in rat liver. Biochem Biophys Res Commun 153: 855-861.
35. Schuckelt R, Brigelius-Flohé R, Maiorino M, Roveri A, Reumkens J, Strassburger W, Flohé L. 1991. Phospholipid hydroperoxide glutathione peroxidase is a selenoenzyme distinct from the classical glutathione peroxidase as evident from cDNA and amino acid sequencing. Free Rad Res Commun 14:343-361.
36. Shen Q, Chu FF, Newburger PE. 1993. Sequences in the 3′-untranslated region of the human cellular glutathione peroxidase gene are necessary and sufficient for selenocysteine incorporation at the UGA codon. J Biol Chem 268:11463-11469.
37. Stadtman TC. 1996. Selenocysteine. Annu Rev Biochem 65:83-100.
38. Steel RGD, Torrie JH. 1960. Principles and procedures of statistics. New York: McGraw-Hill.
39. Sunde RA. 1994. Intracellular glutathione peroxidases - Structure, regulation and function. In: Burk RF, ed. Selenium in biology and human health, 5th ed. New York: Springer-Verlag, pp 45-77.
40. Sunde RA. 1997. Selenium. In: O'Dell BL, Sunde RA, eds. Handbook of nutritionally essential mineral elements. New York: Marcel Dekker. pp 493-556.
41. Sunde RA, Dyer JA, Moran TV, Evenson JK, Sugimoto M. 1993. Phospholipid hydroperoxide glutathione peroxidase: Full-length pig blastocyst cDNA sequence and regulation by selenium status. Biochem Biophys Res Commun 193:905-911.
42. Toyoda H, Himeno S, Imura N. 1990. Regulation of glutathione peroxidase mRNA level by dietary selenium manipulation. Biochim Biophys Acta 1049:213-215.
43. Weiss SL, Evenson JK, Thompson KM, Sunde RA. 1996. The selenium requirement for glutathione peroxidase mRNA level is half of the selenium requirement for glutathione peroxidase activity in female rats. J Nutr 126:2260-2267.
44. Weiss SL, Evenson JK, Thompson KM, Sunde RA. 1997. Dietary selenium regulation of glutathione peroxidase mRNA and other selenium-dependent parameters in male rats. J Nutr Biochem 8:85-91.
45. Weiss SL, Sunde RA. 1996. Mutations within the glutathione peroxidase 3′ untranslated region can eliminate selenium regulation of glutathione peroxidase mRNA levels. FASEB J 10:A557. [Abstr]
46. Weiss SL, Sunde RA. 1997a. Selenium regulation of glutathione peroxidase expression requires the 3′ untranslated region in Chinese hamster ovary cells. J Nutr 127:1304-1310.
47. Weiss SL, Sunde RA. 1997b. Selenium regulation of glutathione peroxidase mRNA levels requires sequences within the mRNA 3′ untranslated region in transfected Chinese hamster ovary cells. In: Fischer PWF, L'Abbe MR, Cockell KA, Gibson RS, eds. Trace elements in man and animals, 9. Ottawa, Canada: NRC Research Press, pp 57-58.
48. Wen W, Sunde RA. 1997. Selenocysteine is inserted into glutathione peroxidase-1 at UGA more efficiently at UGA codons in the middle of the coding region than in regions close to the 5′ or 3′ ends of the coding region. FASEB J 11:A236. [Abstr]
49. Yoshimura S, Takekoshi S, Wantanabe K, Fujii-Kuriyama Y. 1988. Determination of nucleotide sequence of cDNA coding rat glutathione peroxidase and diminished expression of the mRNA in selenium deficient rat liver. Biochem Biophys Res Commun 154:1024-1028.