Increased physical activity and the growth hormone-IGF-I axis in adolescent males

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 275, Issue 1 44-1, 1998, Pages

  Eliakim, Alon ^a   Brasel, Jo Anne ^a   Mohan, Subburaman ^b   Wong, Wai Lee T ^c   Cooper, Dan M ^d,e  

^a HARBOR UCLA MEDICAL CENTER   (United States)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GENENTECH INC   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Binding proteins; Energy expenditure; Insulin like growth factor I; Magnetic resonance imaging; Muscle volume

Indexed keywords

GROWTH HORMONE;

ADOLESCENT; ARTICLE; ENERGY EXPENDITURE; EXERCISE; HUMAN; HUMAN EXPERIMENT; HYPOTHESIS; MUSCLE MASS; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN BINDING;

EID: 0031870556     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1998.275.1.r308     Document Type: Article

References (54)

1. Adams, G. R., and F. Haddad. The relationships among IGF-I, DNA content, and protein accumulation during skeletal muscle hypertrophy. J. Appl. Physiol. 81: 2509-2516, 1996.
2. Ambler, C., A. Eliakim, J. A. Brasel, W.-N. P. Lee, G. Burke, and D. M. Cooper. Fitness and the effect of exercise training on the dietary intake of healthy adolescents. Int. J. Obes. 22: 354-362, 1998.
3. Bang, P., J. Brandt, M. Degerblad, G. Enberg, L. Kaijser, M. Thoren, and K. Hall. Exercise-induced changes in insulin-like growth factors and their low molecular weight binding protein in healthy subjects and patients with growth hormone deficiency. Eur. J. Clin. Invest. 20: 285-292, 1990.
4. Blum, W. F., K. Albertsson-Wikland, S. Rosberg, and M. B. Ranke. Serum levels of insulin-like growth factor-I (IGF-I) and IGF binding protein-3 reflect spontaneous growth hormone secretion. J. Clin. Endocrinol. Metab. 76: 1610-1616, 1993.
5. Cappon, J., J. A. Brasel, S. Mohan, and D. M. Cooper. Effect of brief exercise on circulating insulin-like growth factor-I. J. Appl. Physiol. 76: 1418-1422, 1994.
6. Carlsson, L. M., A. M. Rowland, R. G. Clark, N. Gesundheit, and W. L. Wong. Ligand-mediated immunofunctional assay for quantitation of growth hormone-binding protein in human blood. J. Clin. Endocrinol. Metab. 73: 1216-1223, 1991.
7. Cooper, D. M. Evidence for and mechanisms of exercise modulation of growth. Med. Sci. Sports Exerc. 26: 733-740, 1994.
8. Cooper, D. M., D. Y. Moromisato, S. Zanconato, M. Moromisato, S. Jensen, and J. A. Brasel. Effect of growth hormone suppression on exercise training and growth responses in young rats. Pediatr. Res. 35: 223-227, 1994.
9. Costin, G., F. R. Kaufman, and J. Brasel. Growth hormone secretory dynamics in subjects with normal stature. J. Pediatr. 115: 537-544, 1989.
10. Cumming, D. C. Hormones and athletic performance. In: Endocrinology and Metabolism, edited by P. Felig, J. D. Baxter, and L. A. Frohman. New York: McGraw-Hill, 1995, p. 1837-1885.
11. Daughaday, W. H., M. Kapadia, and I. Mariz. Serum somatomedin binding proteins: physiologic significance and interference in radioligand assay. J. Lab. Clin. Med. 109: 355-363, 1987.
12. DeVol, D. L., P. Rotwein, J. L. Sadow, J. Novakofski, and P. J. Bechtel. Activation of insulin-like growth factor gene expression during work-induced skeletal muscle growth. Am. J. Physiol. 259 (Endocrinol. Metab. 22): E89-E95, 1990.
13. Elia, M. Converting carbon dioxide production to energy expenditure. In: The Doubly-Labelled Water Method for Measuring Energy Expenditure: Technical Recommendation for Use in Humans, edited by A. M. Prentice. Vienna: International Atomic Energy Agency, 1990, p. 193-210.
14. Eliakim, A., T. J. Barstow, J. A. Brasel, H. Ajie, W.-N. P. Lee, R. Renslo, N. Berman, and D. M. Cooper. The effect of exercise training on energy expenditure, muscle volume, and maximal oxygen uptake in adolescent females. J. Pediatr. 129: 537-543, 1996.
15. Eliakim, A., J. A. Brasel, T. J. Barstow, S. Mohan, and D. M. Cooper. Peak oxygen uptake, muscle volume, and the growth hormone-insulin-like growth factor-I axis in adolescent males. Med. Sci. Sports Exerc. In press.
16. Eliakim, A., J. A. Brasel, S. Mohan, T. J. Barstow, N. Berman, and D. M. Cooper. Physical fitness, endurance training, and the GH-IGF-I system in adolescent females. J. Clin. Endocrinol. Metab. 81: 3986-3992, 1996.
17. Eliakim, A., L. G. Raisz, J. A. Brasel, and D. M. Cooper. Evidence for increased bone formation following a brief endurance-type training intervention in adolescent males. J. Bone Miner. Res. 12: 1708-1713, 1997.
18. Frost, R. A., S. A. Nachman, C. H. Lang, and M. C. Gelato. Proteolysis of insulin-like growth factor-binding protein-3 in human immunodeficiency virus-positive children who fail to thrive. J. Clin. Endocrinol. Metab. 81: 2957-2962, 1996.
19. Giudice, L. C., E. M. Farrell, H. Pham, G. Lamson, and R. G. Rosenfeld. Insulin-like growth factor binding proteins in maternal serum throughout gestation and in the peurperium: effects of a pregnancy associated serum protease activity. J. Clin. Endocrinol. Metab. 71: 806-817, 1991.
20. Goldberg, A. L. Work-induced growth of skeletal muscle in normal and hypophysectomized rats. Am. J. Physiol. 213: 1193-1198, 1967.
21. Gulve, E. A., K. J. Rodnick, E. J. Henriksen, and J. O. Holloszy. Effects of wheel running on glucose transporter (GLUT4) concentration in skeletal muscle of young and old rats. Mech. Ageing Dev. 67: 187-200, 1993.
22. Hills, F. A., J. English, and T. Chard. Circulating levels of IGF-I and IGF-binding protein-1 throughout pregnancy: relation to birthweight and maternal weight. J. Endocrinol. 148: 303-309, 1996.
23. Honda, Y., E. C. Landale, D. D. Strong, D. J. Baylink, and S. Mohan. Recombinant synthesis of insulin-like growth factor binding protein-4 (IGFBP-4): development, validation, and application of a radioimmunoassay for IGFBP-4 in human serum and other biological fluids. J. Clin. Endocrinol. Metab. 81: 1389-1396, 1996.
24. Jahreis, G., E. Kauf, G. Frohner, and H. E. Schmidt. Influence of intensive exercise on insulin-like growth factor I, thyroid and steroid hormones in female gymnasts. Growth Regul. 1: 95-99, 1991.
25. Jorgensen, J. O., S. B. Pedersen, J. Borglum, J. Frystyk, K. K. Ho, J. S. Christiansen, H. Orskov, W. F. Blum, and B. Richelsen. Serum concentration of insulin-like growth factors, IGF binding proteins 1 and 3, and growth hormone binding proteins in obese women and the effect of growth administration: a double-blind, placebo controlled study. Eur. J. Endocrinol. 133: 65-70, 1995.
26. Kelley, P. J., J. A. Eisman, M. C. Stuart, N. A. Pocock, P. N. Sambrook, and T. H. Gwinn. Somatomedin-c, physical fitness, and bone density. J. Clin. Endocrinol. Metab. 70: 718-723, 1990.
27. Lamson, G., L. C. Giudice, P. Cohen, F. Liu, S. Gargosky, H. L. Muller, Y. Oh, K. F. Wilson, R. L. Hintz, and R. G. Rosenfeld. Proteolysis of IGFBP-3 may be a common regulatory mechanism of IGF action in vivo. Growth Regul. 3: 91-95, 1993.
28. Le Roith, D. Insulin-like growth factors. N. Engl. J. Med. 336: 633-640, 1997.
29. Lee, D. Y., D. H. Yang, C. W. Kang, S. J. Kim, C. U. Joo, S. C. Cho, and J. S. Kim. Serum insulin-like growth factors IGFs and IGF binding protein IGFBP-3 in patients with gastric cancer: IGFBP-3 protease activity induced by surgery. J. Korean Med. Sci. 12: 32-39, 1997.
30. Lowe, W. L., Jr. Biological actions of the insulin-like growth factors. In: Insulin-Like Growth Factors: Molecular and Cellular Aspects, edited by D. Le Roith. Boca Raton, FL: CRC, 1991, p. 49-86.
31. Malarkey, W. B., J. C. Hall, D. K. Pearl, J. K. Kiecolt-Glaser, and R. Glaser. The influence of academic stress and season on 24 hour concentration of growth hormone and prolactin. J. Clin. Endocrinol. Metab. 73: 1089-1092, 1991.
32. Mohan, S., C. Libanati, C. Dony, K. Lang, N. Srinivasan, and D. J. Baylink. Development, validation, and application of a radioimmunoassay for insulin-like growth factor binding protein-5 in human serum and other biological fluids. J. Clin. Endocrinol. Metab. 80: 2638-2645, 1995.
33. Mohan, S., Y. Nakao, Y. Honda, E. Landale, U. Leser, C. Dony, K. Lang, and D. J. Baylink. Studies on the mechanisms by which insulin-like growth factor (IGF) binding protein-4 (IGFBP-4) and IGFBP-5 modulate IGF actions in bone cells. J. Biol. Chem. 270: 20424-20431, 1995.
34. Mohnike, K., U. Kluba, W. F. Blum, V. Aumann, P. Vorwerk, and U. Mittler. Serum concentrations of insulin-like growth factors (IGF)-I and IGF-II and IGF binding proteins (IGFBP)-2 and IGFBP-3 in 49 children with ALL, NHL or solid tumors. Klin. Padiatr. 207: 225-229, 1995.
35. Moromisato, D. Y., M. Y. Moromisato, S. Zanconato, C. T. Roberts, Jr., and D. M. Cooper. Effect of hypoxia on lung, heart, and liver insulin-like growth factor-I gene and receptor expression in the newborn rat. Crit. Care Med. 24: 919-924, 1996.
36. National Institutes of Health. Healthy People 2000: National Health Promotion and Disease Prevention Objectives; [DHHS Publication No. (NIH) 91-50213, 1990, NIH, Bethesda, MD 20892].
37. Parkkola, R., U. Kujala, and U. Rytokoski. Response of the trunk muscles to training assessed by magnetic resonance imaging and muscle strength. Eur. J. Appl. Physiol. 65: 383-387, 1992.
38. Poehlman, E. T., and K. C. Copeland. Influence of physical activity on insulin-like growth factor-I in healthy younger and older men. J. Clin. Endocrinol. Metab. 71: 1468-1473, 1990.
39. Postel-Vinay, M. C., C. Saab, and M. Gourmelen. Nutritional status and growth hormone binding protein. Horm. Res. 44: 177-181, 1995.
40. Quarmby, V., R. Chestnut, and C. Quan. What do total IGF-I immunoassays actually measure? Impact of IGF-I standard quality on quantitation (Abstract). The Endocrine Society Program and Abstracts, Bethesda, MD: Endocrine Society, 1997, p. 467.
41. Rechler, M. M. Insulin-like growth factor binding proteins. Vitam. Horm. 47: 1-114, 1993.
42. Roman, W. J., J. Fleckenstein, J. Stray-Gundersen, S. E. Alway, R. Peshock, and W. J. Gonyea. Adaptations in the elbow flexors of elderly males after heavy-resistance training. J. Appl. Physiol. 74: 750-754, 1993.
43. Rosenfeld, R. G. Circulating growth hormone binding proteins. Horm. Res. 42: 129-132, 1994.
44. Schoeller, D. A., E. Ravussin, Y. Schutz, K. J. Acheson, P. Baertschi, and E. Jequier. Energy expenditure by doubly labeled water: validation in humans and proposed calculation. Am. J. Physiol. 250 (Regulatory Integrative Comp. Physiol. 19): R823-R830, 1986.
45. Schwarz, A. J., J. A. Brasel, R. L. Hintz, S. Mohan, and D. M. Cooper. Acute effect of brief low- and high-intensity exercise on circulating IGF-I, II, and IGF binding protein-3 and its proteolysis in young healthy men. J. Clin. Endocrinol. Metab. 81: 3492-3497, 1996.
46. Smith, W. J., L. E. Underwood, and D. R. Clemmons. Effects of caloric or protein restriction on insulin-like growth factor-I (IGF-I) and IGF-binding proteins in children and adults. J. Clin. Endocrinol. Metab. 80: 443-449, 1995.
47. Strasburger, C., G. Barnard, L. Toldo, B. Zarmi, Z. Zadik, A. Kowarski, and F. Kohen. Somatotropin as measured by a two-site time resolved immunofluorometric assay. Clin. Chem. 35: 913-917, 1989.
48. Suikkari, A. M., T. Sane, M. Seppala, H. Yki Jarvinen, S. L. Karonen, and V. A. Koivisto. Prolonged exercise increases serum insulin-like growth factor-binding protein concentrations. J. Clin. Endocrinol. Metab. 68: 141-144, 1989.
49. Tonshoff, B., W. F. Blum, A. M. Wingen, and O. Mehls. Serum insulin-like growth factors (IGFs) and IGF binding proteins 1, 2, and 3 in children with chronic renal failure: relationship to height and glomerular filtration rate. The European Study Group for Nutritional Treatment of Chronic Renal Failure in Childhood. J. Clin. Endocrinol. Metab. 80: 2684-2691, 1995.
50. Veldhuis, J. D., A. Iranmanesh, K. K. Ho, M. J. Waters, M. L. Johnson, and G. Lizarralde. Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man. J. Clin. Endocrinol. Metab. 72: 51-59, 1991.
51. Wabitsch, M., W. F. Blum, R. Muche, E. Heinze, C. Haug, and W. Teller. Insulin-like growth factors and their binding proteins before and after weight loss and their associations with hormonal and metabolic parameters in obese adolescent girls. Int. J. Obes. 20: 1073-1080, 1996.
52. Weitzman, E. D., A. S. DeGraff, J. F. Sassin, T. Hansen, O. B. Godtlibsen, M. Perlow, and L. Hellman. Seasonal patterns of sleep stages and secretion of cortisol and growth hormone during 24 hour periods in northern Norway. Acta Endocrinol. 78: 65-76, 1975.
53. Weltman, A., J. Y. Weltman, M. L. Hartman, R. D. Abbot, A. D. Rogol, W. S. Evan, and J. D. Veldhuis. Relationship beween age, percentage body fat, fitness, and 24-hour growth hormone release in healthy young adults: effects of gender. J. Clin. Endocrinol. Metab. 78: 543-548, 1994.
54. Zanconato, S., D. Y. Moromisato, M. Y. Moromisato, J. Woods, J. A. Brasel, D. Leroith, C. T. Roberts, Jr., and D. M. Cooper. Effect of training and growth hormone suppression on insulin-like growth factor-I mRNA in young rats. J. Appl. Physiol. 76: 2204-2209, 1994.