Effect of hypoxia on lung, heart, and liver insulin-like growth factor-I gene and receptor expression in the newborn rat

Critical Care Medicine

Volumn 24, Issue 6, 1996, Pages 919-924

  Moromisato, David Y ^a   Moromisato, Mark Y ^a   Zanconato, Stefania ^a   Roberts Jr , Charles T ^b   Brasel, Jo Anne ^a   Cooper, Dan M ^a  

^a HARBOR UCLA MEDICAL CENTER   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

critical illness; development; gene expression; growth; heart; hypoxia; Insulin like growth factor I; liver; lung; oxygen

Indexed keywords

MESSENGER RNA; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY GROWTH; CONTROLLED STUDY; CRITICAL ILLNESS; GENE EXPRESSION; HEART DEVELOPMENT; HYPOXIA; LIVER DEVELOPMENT; LUNG DEVELOPMENT; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; TISSUE SPECIFICITY;

ANIMALS; ANIMALS, NEWBORN; ANOXIA; BINDING, COMPETITIVE; BODY WEIGHT; EATING; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; INSULIN-LIKE GROWTH FACTOR I; LIVER; LUNG; ORGAN SIZE; PROSPECTIVE STUDIES; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, IGF TYPE 1;

EID: 0030006970     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199606000-00008     Document Type: Article

References (32)

1. Wojnar MM, Fan J, Frost RA, et al: Alterations in the insulin-like growth factor system in trauma patients. Am J Physiol 1995; 268:R970-R977
2. Fan J, Char D, Kolasa AJ, et al: Alterations in hepatic production and peripheral clearance of IGF-I after endotoxin. Am J Physiol 1995; 269:E33-E42
3. Bernstein D, Jasper JR, Rosenfeld RG, et al: Decreased serum insulin-like growth factor-I associated with growth failure in newborn lambs with experimental cyanotic heart disease. J Clin Invest 1992; 89:1128-1132
4. Keith JD: Physical growth in infants and children with congenital heart disease. In: Heart Disease in Infancy and Childhood. Third Edition. Keith JD, Rowe RD, Vlad P (Eds). New York, Macmillan Publishing, 1978, pp 200-202
5. Bierman CW, Pearlman DS: Asthma. In: Disorders of the Respiratory Tract in Children. Fifth Edition. Chernick V (Ed). Philadelphia, WB Saunders, 1990, pp 557-601
6. Mortola JP, Xu LJ, Lauzon AM: Body growth, lung and heart weight, and DNA content in newborn rats exposed to different levels of chronic hypoxia. Can J Physiol Pharmacol 1990; 68:1590-1594
7. Russell-Jones DL, Leach RM, Ward JP, et al: Insulin-like growth factor-I gene expression is increased in the right ventricular hypertrophy induced by chronic hypoxia in the rat. J Mol Endocrinol 1993; 10:99-102
8. Phillip M, Werner H, Palese T, et al: Differential accumulation of insulin-like growth factor-I in kidneys of pre- and postpubertal streptozotocin-diabetic rats. J Mol Endocrinol 1994; 12: 215-224
9. Moats-Staats BM, Price WA, Xu L, et al: Regulation of the insulin-like growth factor system during normal rat lung development. Am J Respir Cell Mol Biol 1995; 12:56-64
10. Cooper DM, Moromisato DY, Zanconato S, et al: Effect of growth hormone suppression on exercise training and growth responses in young rats. Pediatr Res 1994; 35:223-227
11. Chomczynski P, Sacchi N: Single step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162:156-159
12. Adamo ML, Ben Hur H, Roberts CT Jr, et al: Regulation of start site usage in the leader exons of the rat insulin-like growth factor-I gene by development, fasting, and diabetes. Mol Endocrinol 1991; 5:1677-1686
13. Werner H, Woloschak M, Adamo M, et al: Developmental regulation of the rat insulin-like growth factor I receptor gene. Proc Natl Acad Sci U S A 1989; 86:7451-7455
14. Lowe WL Jr, Roberts CT Jr, Lasky SR, et al: Differential expression of alternative 5′ untranslated regions in mRNAs encoding rat insulin-like growth factor I. Proc Natl Acad Sci U S A 1987; 84: 8946-8950
15. Havrankova J, Roth J, Brownstein M: Insulin receptors are widely distributed in the central nervous system of the rat. Nature 1979; 272:827-829
16. Lowe WL, Adamo M, Werner H, et al: Regulation by fasting of rat insulin-like growth factor I and its receptor. Effects on gene expression and binding. J Clin Invest 1989; 84:619-626
17. Lowry OH, Rosebrough NJ, Farr AL, et al: Protein measurement with Folin phenol reagent. J Biol Chem 1951; 193: 265-268
18. Munson PJ: A User's Guide to LIGAND: Data analysis and curve-fitting for ligand binding experiments. Bethesda, MD, Division of Computer Research and Technology, National Institutes of Health, 1992, pp 31-87
19. Munson PJ, Rodbard D: LIGAND: A versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 1980; 107:220-239
20. Zanconato S, Moromisato DY, Moromisato MY, et al: Effect of training and growth hormone suppression on insulin-like growth factor-I mRNA in young rats. J Appl Physiol 1994; 76: 2204-2209
21. Foyt HL, Lanau F, Woloshcak M, et al: Effect of growth hormone on levels of differentially processed insulin-like growth factor I mRNAs in total and polysomal mRNA populations. Mol Endocrinol 1992; 6:1881-1888
22. Lechner AJ: Starvation-induced organ hypoplasia in prenatal and postnatal guinea pigs. Biol Neonate 1985; 48:36-42
23. Kalenga M, Henquin JC: Protein deprivation from the neonatal period impairs lung development in the rat. Pediatr Res 1987; 22:45-49
24. Wahlander H, Isgaard J, Jennische E, et al: Left ventricular insulin-like growth factor I increases in early renal hypertension. Hypertension 1992; 19: 25-32
25. Fuller SJ, Mynett JR, Sugden PH: Stimulation of cardiac protein synthesis by insulin-like growth factors. Biochem J 1992; 282:85-90
26. Bartlett D Jr: Postnatal growth of the mammalian lung: Influence of low and high oxygen tensions. Respir Physiol 1970; 9:58-64
27. Winick M, Noble A: Cellular response in rats during malnutrition at various ages. J Nutr 1966; 89:300-306
28. Iwamoto HS, Murray MA, Chernausek SD: Effects of acute hypoxemia on insulin-like growth factors and their binding proteins in fetal sheep. Am J Physiol 1992; 263:E1151-E1156
29. Cunningham EL, Brody JS, Jain BP: Lung growth induced by hypoxia. J Appl Physiol 1974; 37:362-366
30. Buch S, Young J, Han RNN, et al: Developmental regulation of IGFs and their receptor genes in neonatal rat lungs exposed to hyperoxia. Abstr. Am J Respir Crit Care Med 1994; 149:446
31. Reiss K, Meggs LG, Li P, et al: Upregulation of IGF1, IGF1-receptor, and late growth related genes in ventricular myocytes acutely after infarction in rats. J Cell Physiol 1994; 158:160-168
32. Price WA, Stiles AD, Moats Staats BM, et al: Gene expression of insulin-like growth factors (IGFs), the type 1 IGF receptor, and IGF-binding proteins in dexamethasone-induced fetal growth retardation. Endocrinology 1992; 130:1424-1432