Helicobacter pylori and Peptic Ulcer Disease

Scandinavian Journal of Gastroenterology

Volumn 31, Issue sup220, 1996, Pages 10-18

  Van Der Hulst, R W M ^a   Tytgat, G N J ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Helicobacter pylori; peptic ulcer disease

Indexed keywords

DUODENUM ULCER; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; PATHOPHYSIOLOGY; PEPTIC ULCER; RECURRENT DISEASE; REVIEW; ANTIBIOTIC THERAPY; BACTERIAL VIRULENCE; CLINICAL TRIAL; CONFERENCE PAPER; GRAM NEGATIVE INFECTION; PREVALENCE; PRIORITY JOURNAL; RECURRENT PEPTIC ULCER; STOMACH ULCER;

DUODENAL ULCER; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; PEPTIC ULCER; RECURRENCE;

ACETYLSALICYLIC ACID; AMOXICILLIN; ANTIBIOTIC AGENT; BISMUTH; CLARITHROMYCIN; METRONIDAZOLE; NONSTEROID ANTIINFLAMMATORY AGENT; OMEPRAZOLE; PROTON PUMP INHIBITOR; RANITIDINE; TETRACYCLINE;

EID: 0029818550     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365529609094744     Document Type: Article

References (118)

1. Rauws E AJ, Langenberg W, Houthoff H J, Zanen H C, Tytgat G NJ. Campylobacter pyloridis-associated chronic antral gastritis. Gastroenterology 1988; 94: 33 – 40
2. NIH Consensus Conference. Helicobacter pylori in peptic ulcer disease. JAMA 1994; 272: 65 – 9
3. Tytgat G NJ, Noach L A, Rauws E AJ. Helicobacter pylori infection and duodenal ulcer disease. Gastroenterol Clin North Am 1993; 22: 127 – 39
4. Sipponen P, Varis K, Frater O, et al. Cumulative 10-year risk of symptomatic duodenal and gastric ulcer in patients with or without chronic gastritis. Scand J Gastroenterol 1990; 25: 966 – 73
5. Vaira D, Miglioli M, Mulé P, et al. Prevalence of peptic ulcer in Helicobacter pylori positive blood donors. Lancet 1994; 35: 309 – 12
6. Graham D Y. Campylobacter pylori and peptic ulcer disease. Gastroenterology 1989; 96: 615 – 25
7. Reinbach D H, Cruickshank G, McColl K EL. Acute perforated duodenal ulcer is not associated with Helicobacter pylori infection. Gut 1993; 34: 1344 – 7
8. McColl K EL, El-Nujumi A M, Chittajallu R S, Dahill S W, Dorrian C A, Graham H, et al. A study of the pathogenesis of Helicobacter pylori-negative chronic duodenal ulcer disease. Gut 1993; 34: 762 – 9
9. Borody T J, George L L, Brandl S, Andrews P, Ostapowicz N, Hyland L, et al. Helicobacter pylori-negative duodenal ulcer. Am J Gastroenterol 1991; 86: 1154 – 7
10. Wensey Y M, Schubert T T, Bologna S D, Ma C K. Helicobacter pylori-negative duodenal ulcer. Am J Med 1991; 91: 15 – 8
11. Dunn B. Pathogenic mechanisms of Helicobacter pylori. Gastroenterol Clin N Am 1993; 22: 43 – 57
12. Yoshida N, Granger D N, Evans D J, Jr, Evans D G, Graham D Y, Anderson D C, et al. Mechanisms involved in Helicobacter pylori-induced inflammation. Gastroenterology 1993; 105: 1431 – 40
13. Dickey W, Collins J SA, Watson R GP, Sloan J M, Porter K G. Secretor status and Helicobacter pylori infection are independent risk factors for gastroduodenal disease. Gut 1993; 34: 351 – 3
14. Graham D Y, Lechago J. Antral G-cell and D-cell numbers in Helicobacter pylori infection: effect of Helicobacter pylori eradication. Gastroenterology 1993; 104: 1655 – 60
15. Graham D Y, Go M F, Lew G M, Genta R M, Rehfeld J F. Helicobacter pylori infection and exaggerated gastrin release. Effects of inflammation and progastrin processing. Scand J Gastroenterol 1993; 28: 690 – 4
16. El-Omar E, Panman I, Dorrian C A, Ardill J ES, McColl K EL. Eradicating Helicobacter pylori infection lowers gastrin mediated acid secretion by two-thirds in patients with duodenal ulcer. Gut 1993; 34: 1060 – 5
17. Dixon M F. Helicobacter pylori and peptic ulceration: histopathological aspects. J Gastroenterol Hepatol 1991; 6: 125 – 30
18. Dixon M F, Sobala G M. Gastritis and duodenitis: the histopathological spectrum. Eur J Gastroenterol Hepatol 1992; 4 Suppl 2: S17 – 23
19. Sobala G M, Axon A TR, Dixon M F. Morphology of chronic gastritis: relationship to age, Helicobacter pylori status and peptic ulceration. Eur J Gastroenterol Hepatol 1992; 4: 825 – 9
20. Axon A TR. Clinical and histological consequences of Helicobacter pylori suppression/eradication. Eur J Gastroenterol Hepatol 1992; 4 Suppl 2: S49 – 52
21. Sipponen P, Seppälä K, Aarynen M, et al. Chronic gastritis and gastroduodenal ulcer: a case control study on risk of coexisting duodenal or gastric ulcer in patients with gastritis. Gut 1989; 30: 922 – 9
22. Matysiak-Budnik T, Poniewierka E, Gasciniak G, Jelen M, Knapik Z. A 5-year follow-up study of the chronic gastritis patients. Ir J Med Sci 1992; 161 Suppl 10: 59
23. Cullen D JE, Collins B J, Christiansen K J, et al. Long-term risk of peptic ulcer disease in people with Helicobacter pylori infection: A community based study. Gut 1993; 34 Suppl 1: 284
24. Wyatt J I, Rathbone B J, Sobala G, et al. The prevalence and distribution of gastric epithelium in the duodenum and its relationship to Helicobacter pylori and inflammation. J Clin Pathol 1990; 43: 981 – 6
25. Noach L A, Rolf T M, Bosma N B, Schwartz M P, Oosting J, Rauws E AJ, Tytgat G NJ. Gastric metaplasia and Helicobacter pylori infection. Gut 1993; 34: 1510 – 4
26. Kreuning J, vd Wal A M, Kuiper G, Lindeman J. Chronic nonspecific duodenitis. A multiple biopsy study of the duodenal bulb in health and disease. Scand J Gastroenterol 1989; 24 Suppl 167: 16 – 20
27. Dixon M. Acid, ulcers, and H. pylori. Lancet 1993; 342: 384 – 5
28. Johnston B J, Reed P I, Alimm H. Campylobacter-like organisms in duodenal and antral endoscopic biopsies: relationship to inflammation. Gut 1986; 27: 1132 – 7
29. Taha A S, Dahill S, Natohabendi I, Lee P D, Sturrock R D, Russell R I. Duodenal histology, ulceration and Helicobacter pylori in the presence or absence of non-steroidal anti-inflammatory drugs. Gut 1993; 34: 1162 – 6
30. Bode G, Malfertheiner P, Mader U, Stanescu A, Ditschunert H. Fine structure of active and heded duodenal ulcer. Am J Gastroenterol 1991; 86: 179 – 86
31. Hessey S T, Spenger J, Wyatt J I. Bacterial adhesion and disease activity in Helicobacter-associated chronic gastritis. Gut 1990; 31: 134 – 8
32. Borén T, Falk P, Roth K A, Larson G, Normark S. Attachment of Helicobacter pylori to human gastric epithelium mediated by blood group antigens. Science 1993; 262: 1892 – 5
33. Cover T L, Dooley C P, Blaser M J. Characterization of and human serologic response to proteins in Helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity. Infect Immun 1990; 58: 603 – 10
34. Cover T L, Puryear W, Perez-Perez G I, Blaser M J. Effect of urease on HeLa cell vacuolation induced by Helicobacter pylori cytotoxin. Infect Immun 1991; 59: 1264 – 70
35. Figura N, Guglielmetti P, Rossolini A, et al. Cytotoxin production by Campylobacter pylori strains isolated from patients with peptic ulcers and from patients with chronic gastritis only. J Clin Microbiol 1989; 27: 225 – 6
36. Leunk R D, Johnson P T, David B C, et al. Cytotoxic activity in broth culture filtrates of Campylobacter pylori. J Med Microbiol 1988; 26: 414 – 7
37. Tee W, Lambert J R, Pegorer M, Dwyer B. Cytotoxin production by H. pylori more common in peptic ulcer disease. Gastroenterology 1993; 104: A789
38. Cover T L, Vaughn S G, Cao P, Blaser M J. Potentiation of Helicobacter pylori vacuolating toxin activity by nicotine and other weak bases. J Infect Dis 1992; 166: 1073 – 8
39. Covacci A, Censini S, Bugnoli M, Petracca R, Burroni D, et al. Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci United States of America 1993; 90: 5791 – 5
40. Blaser M J. Pathogenesis of Helicobacter pylori infection. Postgraduate Course AGA 1993; 113 – -7, Boston
41. Van der Hulst R WM, Weel J FL, Gerrits Y, et al. Use of PCR and DNA hybridization in determining CagA among Helicobacter pylori isolates from peptic ulcer and non-ulcer patients. Proceedings of the Spring Meeting of the Dutch Society of Gastroenterology and Hepatology, Veldhoven. 1995, Neth J Med 1995, 47, A33
42. Xiang Z, Censini S, Bayelli P F, et al. Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be devided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin. Infect Immun 1995; 63: 94 – 8
43. Crabtree J E, Taylor J D, Wyatt J E, Heatley R V, Shallcross T M, Tompkins D S, Rathbone B J. Mucosal IgA recognition of Helicobacter pylori 120 kDA protein, peptic ulceration and gastric pathology. Lancet 1991; 338: 332 – 5
44. Crabtree J E, Taylor J D, Wyatt J I, Heatley R V, Shallcross T M, Tompkins D S, Rathbone B J. Mucosal IgA recognition of Helicobacter pylori 120 kDa protein, peptic ulceration, and gastric pathology. Lancet 1991; 338: 332 – 5
45. Rautelin H, Blomberg B, Fredlund H, Jarnerot G, Danielsson D. Incidence of Helicobacter pylori strains activating neutrophils in patients with peptic ulcer disease. Gut 1993; 34: 599 – 603
46. Davies G R, Simmonds N J, Steuns J RJ, Gandison A, Blake D R, Rampton D S. Mucosal reactive oxygen metabolite production in duodenal ulcer disease. Gut 1992; 33: 1467 – 72
47. Yoshimura H A, Evans D G, Graham D Y. H. pylori strains from duodenal ulcer patients differ at the genomic level from those from patients with simple gastritis. Rev Esp Enf Digest 1990; 78 Suppl 1: 22 – 9
48. Go M F, Tran L, Chan K Y, Versalovic J, Kocuth T, Graham D Y, Lupski J R. REP-PCR fingerprint analysis reveals gastroduodenal disease-specific clusters of H. pylori strains. Am J Gastroenterol 1993; 88: 1591
49. Salmela K S, Roine R P, Koivisko, et al. Characteristics of Helicobacter pylori alcohol dehydrogenase. Gastroenterology 1993; 105: 325 – 30
50. Jablonowski H, Hengels K K, Savade C, Strohmeyer G. Helicobacter pylori (Hp) from patients with gastritis inhibit acid production more frequently than Hp from duodenal ulcer patients. Gastroenterology 1993; 104: A110
51. Daw M A, Cotter L, Healy M, O'Moore R., Keane C T, O'Morain C. Are Helicobacter pylori strains isolated from duodenal ulcer patients more virulent than those isolated from gastritis?. Gastroenterology 1991; 100: 572A
52. Rautelin H, Blomberg B, Jarnerot G, Danielsson D. Nonopsonic activation of neutrophils and cytotoxin production by Helicobacter pylori: ulcerogenic markers. Scand J Gastroenterol 1994; 29: 128 – 32
53. Bell G D, Powell K U, Burridge S M, Harrison G, Rameh B, et al. Reinfection or recrudescence after apparently successful eradication of Helicobacter pylori infection: implications for treatment of patients with duodenal ulcer disease. Q J Med 1993; 86: 375 – 82
54. Borody T J, Andrews P, Mancuso N, et al. Helicobacter reinfection rate in patients with cured duodenal ulcer. Am J Gastroenterol 1994; 89: 529 – 32
55. Logan R PH, Gummett P A, Poison R J, et al. The recurrence of Helicobacter pylori in relation to duodenal ulcer. Rev Esp Enf Digest 1990; 78 Suppl 1: 72 – 73, (P-152).
56. George L L, Borody T J, Andrews P, Devine M, Moore-Jones D, Walton M, et al. Cure of duodenal ulcer after eradication of Helicobacter pylori. Med J Aust 1990; 153: 145 – 9
57. Hepps K S, Lamirez F C, Lew G M, Szaad S A, Graham D Y. Treatment of H. pylori reduces the rate of rebleeding in complicated peptic ulcer disease. Gastrointest Endosc 1992; 38: 234A
58. Labenz J, Borsch G. Role of Helicobacter pylori eradication in the prevention of peptic ulcer bleeding relapse. Digestion 1994; 55: 19 – 23
59. Graham D Y, Hepps K S, Ramirez F C, Lew G M, Saled J A. Treatment of Helicobacter pylori reduces the rate of rebleeding in peptic ulcer disease. Scand J Gastroenterol 1993; 28: 939 – 42
60. Rokkas T, Karamesis A, Maurogeorgis A, et al. Eradication of Helicobacter pylori reduces the possibility of rebleeding in peptic ulcer disease. Gastrointest Endosc 1995; 41: 1 – 4
61. Jaspersen D, Koerner T, Schors W, et al. Helicobacter pylori eradication reduces the rate of rebleeding in ulcer hemorrhage. Gastrointest Endosc 1995; 41: 5 – 7
62. Reinbach D H, Gruickshank G, McColl K EL. Acute perforated duodenal ulcer is not associated with Helicobacter pylori infection. Gut 1993; 34: 1344 – 7
63. Debongie J C, Legros G. Gastric perforation; an acute disease unrelated to H. pylori?. Rev Esp Enferm Dig 1990; 78L Suppl 1: 71 – 2
64. Craanen M E, Dekker W, Blok P, Ferweda J, Tytgat G NJ. Intestinal metaplasia and Helicobacter pylori: an endoscopic biopsy study of the gastric antrum. Gut 1992; 33: 16 – 20
65. Correa P, Haenszel W, Cuello C, et al. Gastric precancerous process in a high-risk population: cohort follow-up. Cancer Res 1990; 50: 4737 – 40
66. Kawano S, Tsujii M, Fusamoto H, Sato N, Kamada T. Chronic effect of intragastric ammonia on gastric mucosal structures in rats. Dig Dis Sci 1991; 36: 33 – 8
67. Negrini R, Lisato L, Zanella I, Cavazzini L, Gullini S, Villanacci V, et al. Helicobacter pylori infection induces antibodies cross-reacting with human gastric mucosa. Gastroenterology 1991; 101: 437 – 45
68. Sobala G M, O'Connor H J, Dewar E P, King R FG, Axon A TR, Dixon M F. Histological consequences of bile reflux on the gastric mucosa, with special reference to intestinal metaplasia. J Clin Pathol (in press)
69. Sobala G M, King R FG, Axon A TR, Dixon M F. Reflux gastritis in the intact stomach. J Clin Pathol 1990; 43: 303 – 6
70. Correa P, Cuello C, Fajardo L F, Haenszel W, Bolanos O, De Ramirez B. Diet and gastric cancer: nutrition survey in a high risk area. J Natl Cancer Inst 1983; 70: 673 – 8
71. Tatsuta M, Iishi H, Okuda S. Effect of cigarette smoking on acid-secreting area and intestinal metaplasia in the stomach. Dig Dis Sci 1988; 33: 23 – 9
72. Lynch D AF, Mepstone N P, Clarke A MT, et al. Cell proliferation in the gastric corpus in Helicobacter pylori associated gastritis and after gastric resection. Gut 1995; 36: 351 – 3
73. Lynch D AF, Mapstone N P, Clarke A MT, et al. Cell proliferation in Helicobacter pylori associated gastritis and the effect of eradication therapy. Gut 1995; 36: 346 – 50
74. Kimura K. Chronological transition of the fundic-pyloric border determined by stepwise biopsy of the lesser and greater curvatures of the stomach. Gastroenterology 1972; 63: 584 – 92
75. Tatsuta M, Okuda S. Location, healing and recurrence of gastric ulcers in relation to fundal gastritis. Gastroenterology 1975; 69: 897 – 902
76. Oi M, Oshida K, Sugimura S. The location of gastric ulcer. Gastroenterology 1969; 36: 45 – 56
77. Oi M, Sakurai Y. The location of duodenal ulcer. Gastroenterology 1959; 36: 60 – 4
78. Dixon M F, Sobala G M, Wyatt J I. Surface epithelial degeneration in H. pylori gastritis; relationship to coexistent peptic ulcer. Irish J Med Sci 1992; Suppl 10: 13
79. Crabtree J E, Figura N, Taylor D JD, Bugnoli M, Armellini D, Tompkins D S. Expression of 120 Kilodalton protein and cytotoxicity in Helicobacter pylori. J Clin Pathol 1992; 45: 733 – 4
80. Sung J JY, Sydney S C, Ling Th KW, et al. Antibacterial treatment of gastric ulcers associated with Helicobacter pylori. N Engl J Med 1995; 332: 139 – 42
81. van der Hulst R WM, Köycü B, Keller J J, Bruno M J, Rauws E AJ, Tytgat G NJ. Helicobacter eradication affects the natural course of gastric ulcer disease; 11 years follow-up. Proceedings 4th United European Gastroenterology Week, Berlin, September, 1995, abstract number 1549, Endoscopy 1995 (in press).
82. Noach L A, Langenberg W L, Bertola M A, et al. Impact of metronidazole resistance on the eradication of Helicobacter pylori. Scand J Infect Dis 1994; 26: 321 – 7
83. Tytgat G NJ. Treatments that impact favourably upon the eradication of Helicobacter pylori and ulcer recurrence. Aliment Pharmacol Ther 1994; 8: 359 – 68
84. Bazzoli F, Zagari R M, Fossi, et al. Short-term low-dose triple therapy for the eradication of Helicobacter pylori. Eur J Gastroenterol Hepatol 1994; 6: 773 – 7
85. De Boer W A, Driessen W MM, Jansz A, Tytgat G NJ. Effect of acid suppression on efficacy of treatment for Helicobacter pylori infection. Lancet 1995; 345: 817 – 20
86. Bayerdörffer E, Kasper G, Pirlet T, Sommer A, Ottenjann R. Ofloxacin in der Therapie Campylobacter pylori—poitiver Ulcera Duodeni. Dtsch Med Wochenschr 1987; 112: 1407 – 11
87. Marshall B J, Goodwin C S, Warren J R, et al. Prospective double-blind trial of duodenal ulcer relapse after eradication of Campylobacter pylori. Lancet 1988; ii: 1437 – 12
88. Graham D Y, Lew G M, Evans D G, et al. Effects of triple therapy (antibiotics plus bismuth) on duodenal ulcer healing. A randomized controlled trial. Ann Intern Med 1991; 115: 266 – 9
89. Mannes G A, Bayerdörffer E, Höchter W, et al. Decreased relapse rate after antibacterial treatment of Helicobacter pylori-associated duodenal ulcers. Munich duodenal ulcer trial. Eur J Gastroenterol Hepatol 1993; 5: 145 – 53
90. Hentschell E, Brandstätter G, Dragosics B, Hirschl A M, Nemec H, Schütze K, et al. Effect of ranitidine and amoxicillin plus metronidazole on the eradication of Helicobacter pylori and the recurrence of duodenal ulcer. New Engl J Med 1993; 312: 308 – 12
91. Coghlan J G, Humphries H, Dooley C, Keane C, Gilligan D, McKenna D, et al. Campylobacter pylori and recurrence of duodenal ulcers: a 12-month follow-up study. Lancet 1987; ii: 1109 – 11
92. Lambert J R, Borromeo M, Korman G, Hansky J, Eaves E R. Effect of colloidal bismuth (DeNol) on healing and relapse of duodenal ulcers: role of Campylobacter pyloridis [abstract]. Gastroenterology 1987; 92: A1489
93. Smith A C, Price A B, Bordello O, Levi A J. A comparison of ranitidine and tripotassium dicitratobismuthate (TDB) in relapse rates of duodenal ulcer: the role of Campylobacter pylori (c.p.) [abstract]. Gastroenterology 1988; 94: A431
94. Borody T, Cole P, Noonan S, Morgan A, Ossip G, Maysey J, et al. Long-term Campylobacter pylori recurrence posteradication [abstract]. Gastroenterology 1988; 94: A43
95. Borody T J, Cole P, Noonan S, Morgan A, Lenne J, Hyland L, et al. Recurrence of duodenal ulcer and Campylobacter pylori infection after eradication. Med J Aust 1989; 151: 431 – 5
96. Rauws E AJ, Tytgat G NJ. Eradication of Helicobacter pylori cures duodenal ulcer disease. Lancet 1990; i: 1233 – 5
97. Blum A L, Armstrong D, Dammann H, Fischer M, Greiner L, Haase W, et al. The effect of Helicobacter pylori on the healing and relapse of duodenal ulcer [abstract]. Gastroenterology 1990; 98: A22
98. Grigorjev P YA, Aruin L I, Isakow V A. De-Nol plus oxacillin versus ranitidine and oxacillin in HP-positive duodenal ulcers: effects on relapse. Rev Esp Enferm Dig 1990; 78 Suppl 1: 129
99. Carrick J, Daskalopoulos G, Mitchell H, Lee A. Successful eradication of H. pylori infection prevents recurrence of duodenal ulceration [abstract]. Rev Esp Enferm Dig 1990; 78 Suppl 1: 122 – 3
100. Patchett S, O'Riordan T O, Leen E, Keane C, O'Morain C. A prospective study of Helicobacter pylori eradication in duodenal ulcer [abstract]. Gastroenterology 1990; 98: A104
101. Lamouliatte H, Bernard P H, Boulard A, Cayla R, de Mascarel A, Mégraud F, et al. Helicobacter pylori eradication prevents duodenal ulcer relapse [abstract]. Gastroenterology 1991; 100: A104
102. Collins R A, Beattie S, O'Morain C. Long-term evaluation of anti-Helicobacter pylori treatment in duodenal ulcer (DU). Monotherapy versus CBS combination therapy (abstract). Gastroenterology 1991; 100: A48
103. Logan R PH, Walker M M, Misiewicz J J, Gummett P A, Poison R J, Karim N Q, et al. Relationship between Helicobacter pylori recurrence and relapse of duodenal ulcer. Gastroenterology 1991; 100: A112
104. Fiocca R, Solcia E, Santoro B. Duodenal ulcer relapse after eradication of Helicobacater pylori [Letter]. Lancet 1991; 337: 1614
105. Sobala G M, Lynch D AF, Gallacher B, Dixon M F, Axon A TR. Eradication of H. pylori prevents duodenal ulcer recurrence [abstract]. Ir J Med Sci 1992; 161 Suppl 10: 89
106. Coelho L GV, Passos M CF, Chausson Y, Costa E L, Maia A F, Brandao M JCC, et al. Duodenal ulcer and eradication of Helicobacter pylori in a developing country. An 18-month follow-up study. Scand J Gastroenterol 1992; 27: 362 – 6
107. Bayerdörffer E, Mannes G A, Sommer A, et al. High-dose omeprazole treatment combined with amoxicillin eradicates Helicobacter pylori. Em. J Gastroenterol Hepatol 1992; 4: 697 – 702
108. Labenz J, Gyenes E, Rühl G H, Borsch G. Hp reinfection and clinical course of ulcer disease in the first year after amoxicillin/omeprazole treatment [abstract]. Ir J Med Sci 1992; 161 Suppl 10: 15 – 6
109. Seppälä K, Färkkilä M, Nuutinen H, Hakala K, Väönänen H, et al. Triple therapy of Helicobacter pylori infection in peptic ulcer. A 12-month follow-up study of 93 patients. Scand J Gastroenterol 1992; 27: 973 – 6
110. Unge P, Gad A, Erikkson K, et al. Amoxicillin added to omeprazole prevents relapse in the treatment of duodenal ulcer patients. Eur J Gastroenterol Hepatol 1993; 5: 325 – 31
111. Vigneri S, Termini R, Scialabba A, DiMario F, Savarino V, Mela G S. One year relapse rate after H. pylori eradication with omeprazole plus antimicrobials. Gastroenterology 1993; 104: A220
112. Chung S CS, Sung J Y, Hosking S W, Lai C W, Yung M Y, Ling T KW, et al. One week therapy for Helicobacter pylori eradication: follow-up study of a randomized trial at one year after treatment. Gastroenterology 1993; 104: A56
113. Balatsos V, Delis V, Skandalis N, Archimandritis A. Triple therapy after duodenal ulcer healing with omeprazole or ranitidine eradicates H. pylori and prevents ulcer relapses: preliminary results of a year follow-up study. Gastroenterology 1993; 104: A37
114. Mantzaris C J, Hatzis A, Tamvakologos G, et al. Prospective, randomized, investigator-blind trial of Helicobacter pylori infection treatment in patients with refractory duodenal ulcers. Healing and long-term relapse rates. Dig Dis Sci 1993; 36: 1132 – 6
115. McCarthy C M, Collins R, Beattie S, Hamilton H, O'Morain C. Treatment of Helicobacter pylori-associated duodenal ulcer with omeprazole plus antibiotics. Aliment Pharmacol Ther 1993; 7: 463 – 6
116. Tatsuta M, Ishikawa H, Iishi H, Okuda S, Yokota Y. Reduction of gastric ulcer recurrence after suppression of Helicobacter pylori by cefixime. Gut 1990; 31: 973 – 6
117. Seppälä K, Pikkarainen P, Karvonen A L, Gormsen H. In the Finnish gastric ulcer study group (FGUSG). The role of Helicobacter pylori eradication, the gastric ulcer healing and relapse. Gastroenterology 1992; 102: A162
118. Bayerdörffer E, Mannes G A, Höchter W, Weingart J, Sommer A, Klann H, et al. Antibacterial treatment of gastric ulcers—German Gastric Ulcer Study. Gastroenterology 1993; 104: A40