-
1
-
-
0019783892
-
Human E apoprotein heterogeneity. Cysteine-arginine interchanges in the amino acid sequence of the apo-E isoforms
-
Weisgraber, K. H., S. C. Rall, Jr., and R. W. Mahley. 1981. Human E apoprotein heterogeneity. Cysteine-arginine interchanges in the amino acid sequence of the apo-E isoforms. J. Biol. Chem. 256: 9077-9083.
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 9077-9083
-
-
Weisgraber, K.H.1
Rall Jr., S.C.2
Mahley, R.W.3
-
2
-
-
0020478765
-
Abnormal lipoprotein receptor-binding activity of the human e apoprotein due to cysteine-arginine interchange at a single site
-
Weisgraber, K. H., T. L. Innerarity, and R. W. Mahley. 1982. Abnormal lipoprotein receptor-binding activity of the human E apoprotein due to cysteine-arginine interchange at a single site. J. Biol. Chem. 257: 2518-2521.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 2518-2521
-
-
Weisgraber, K.H.1
Innerarity, T.L.2
Mahley, R.W.3
-
3
-
-
0024299370
-
Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
-
Mahley, R. W. 1988. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science. 240: 622-630.
-
(1988)
Science
, vol.240
, pp. 622-630
-
-
Mahley, R.W.1
-
4
-
-
0028303072
-
Apolipoprotein E: Structure-function relationships
-
Weisgraber, K. H. 1994. Apolipoprotein E: structure-function relationships. Adv. Protein Chem. 45: 249-302.
-
(1994)
Adv. Protein Chem.
, vol.45
, pp. 249-302
-
-
Weisgraber, K.H.1
-
5
-
-
0001575895
-
Type III hyperlipoproteinemia (dysbetalipoproteinemia): The role of apolipoprotein E in normal and abnormal lipoprotein metabolism
-
C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle, editors. McGraw-Hill, New York
-
Mahley, R. W., and S. C. Rail, Jr. 1995. Type III hyperlipoproteinemia (dysbetalipoproteinemia): the role of apolipoprotein E in normal and abnormal lipoprotein metabolism. In The Metabolic and Molecular Bases of Inherited Disease. 7th edition. C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle, editors. McGraw-Hill, New York. 1953-1980.
-
(1995)
The Metabolic and Molecular Bases of Inherited Disease. 7th Edition
, pp. 1953-1980
-
-
Mahley, R.W.1
Rail Jr., S.C.2
-
6
-
-
0022493049
-
Apolipoprotein E3-Leiden. A new variant of human apolipoprotein E associated with familial type III hyperlipoproteinemia
-
Havekes, L., E. de Wit, J. G. Leuven, E. Klasen, G. Utermann, W. Weber, and U. Beisiegel. 1986. Apolipoprotein E3-Leiden. A new variant of human apolipoprotein E associated with familial type III hyperlipoproteinemia. Hum. Genet. 73: 157-163.
-
(1986)
Hum. Genet.
, vol.73
, pp. 157-163
-
-
Havekes, L.1
De Wit, E.2
Leuven, J.G.3
Klasen, E.4
Utermann, G.5
Weber, W.6
Beisiegel, U.7
-
7
-
-
0024820009
-
Apolipoprotein E3-Leiden contains a seven-amino acid insertion that is a tandem repeat of residues 121-127
-
Wardell, M. R., K. H. Weisgraber, L. M. Havekes, and S. C. Rall, Jr. 1989. Apolipoprotein E3-Leiden contains a seven-amino acid insertion that is a tandem repeat of residues 121-127. J. Biol. Chem. 264: 21205-21210.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 21205-21210
-
-
Wardell, M.R.1
Weisgraber, K.H.2
Havekes, L.M.3
Rall Jr., S.C.4
-
8
-
-
0023937366
-
Human apolipoprotein E3 in aqueous solution. II. Properties of the amino- And carboxyl-terminal domains
-
Aggerbeck, L. P., J. R. Wetterau, K. H. Weisgraber, G-S. C. Wu, and F. T. Lindgren. 1988. Human apolipoprotein E3 in aqueous solution. II. Properties of the amino- and carboxyl-terminal domains. J. Biol. Chem. 263: 6249-6258.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 6249-6258
-
-
Aggerbeck, L.P.1
Wetterau, J.R.2
Weisgraber, K.H.3
Wu, G.-S.C.4
Lindgren, F.T.5
-
9
-
-
0023900109
-
Human apolipoprotein E3 in aqueous solution. I. Evidence for two structural domains
-
Wetterau, J. R., L. P. Aggerbeck, S. C. Rail, Jr., and K. H. Weisgraber. 1988. Human apolipoprotein E3 in aqueous solution. I. Evidence for two structural domains. J. Biol. Chem. 263: 6240-6248.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 6240-6248
-
-
Wetterau, J.R.1
Aggerbeck, L.P.2
Rail Jr., S.C.3
Weisgraber, K.H.4
-
10
-
-
0021031302
-
The receptor-binding domain of human apolipoprotein E. Binding of apolipoprotein E fragments
-
Innerarity, T. L., E. J. Friedlander, S. C. Rall, Jr., K. H. Weisgraber, and R. W. Mahley. 1983. The receptor-binding domain of human apolipoprotein E. Binding of apolipoprotein E fragments. J. Biol. Chem. 258: 12341-12347.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 12341-12347
-
-
Innerarity, T.L.1
Friedlander, E.J.2
Rall Jr., S.C.3
Weisgraber, K.H.4
Mahley, R.W.5
-
11
-
-
0023835033
-
Site-specific mutagenesis of human apolipoprotein E. Receptor binding activity of variants with single amino acid substitutions
-
Lalazar, A., K. H. Weisgraber, S. C. Rall, Jr., H. Giladi, T. L. Innerarity, A. Z. Levanon, J. K. Boyles, B. Amit, M. Gorecki, R. W. Mahley, and T. Vogel. 1988. Site-specific mutagenesis of human apolipoprotein E. Receptor binding activity of variants with single amino acid substitutions. J. Biol. Chem. 263: 3542-3545.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 3542-3545
-
-
Lalazar, A.1
Weisgraber, K.H.2
Rall Jr., S.C.3
Giladi, H.4
Innerarity, T.L.5
Levanon, A.Z.6
Boyles, J.K.7
Amit, B.8
Gorecki, M.9
Mahley, R.W.10
Vogel, T.11
-
12
-
-
0021028813
-
The receptor-binding domain of human apolipoprotein E. Monoclonal antibody inhibition of binding
-
Weisgraber, K., H., T. L. Innerarity, K. J. Harder, R. W. Mahley, R. W. Milne, Y. L. Marcel, and J. T. Sparrow. 1983. The receptor-binding domain of human apolipoprotein E. Monoclonal antibody inhibition of binding. J. Biol. Chem. 258: 12348-12354.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 12348-12354
-
-
Weisgraber, K.H.1
Innerarity, T.L.2
Harder, K.J.3
Mahley, R.W.4
Milne, R.W.5
Marcel, Y.L.6
Sparrow, J.T.7
-
13
-
-
0028774042
-
Salt bridge relay triggers defective LDL receptor binding by a mutant apolipoprotein
-
Wilson, C., T. Mau, K. H. Weisgraber, M. R. Wardell, R. W. Mahley, and D. A. Agard. 1994. Salt bridge relay triggers defective LDL receptor binding by a mutant apolipoprotein. Structure. 2: 713-718.
-
(1994)
Structure
, vol.2
, pp. 713-718
-
-
Wilson, C.1
Mau, T.2
Weisgraber, K.H.3
Wardell, M.R.4
Mahley, R.W.5
Agard, D.A.6
-
14
-
-
0021211156
-
Normalization of receptor binding of apolipoprotein E2. Evidence for modulation of the binding site conformation
-
Innerarity, T. L., K. H. Weisgraber, K. S. Arnold, S. C. Rall, Jr., and R. W. Mahley. 1984. Normalization of receptor binding of apolipoprotein E2. Evidence for modulation of the binding site conformation. J. Biol. Chem. 259: 7261-7267.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 7261-7267
-
-
Innerarity, T.L.1
Weisgraber, K.H.2
Arnold, K.S.3
Rall Jr., S.C.4
Mahley, R.W.5
-
15
-
-
0029784503
-
Novel mechanism for defective receptor binding of apolipoprotein E2 in type III hyperlipoproteinemia
-
Dong, L-M., S. Parkin, S. D. Trakhanov, B. Rupp, T. Simmons, K. S. Arnold, Y. M. Newhouse, T. L. Innerarity, and K. H. Weisgraber. 1996. Novel mechanism for defective receptor binding of apolipoprotein E2 in type III hyperlipoproteinemia. Nat. Struct. Biol. 3: 718-722.
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 718-722
-
-
Dong, L.-M.1
Parkin, S.2
Trakhanov, S.D.3
Rupp, B.4
Simmons, T.5
Arnold, K.S.6
Newhouse, Y.M.7
Innerarity, T.L.8
Weisgraber, K.H.9
-
16
-
-
0023806075
-
Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase
-
Smith, D. B., and K. S. Johnson. 1988. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene, 67: 31-40.
-
(1988)
Gene
, vol.67
, pp. 31-40
-
-
Smith, D.B.1
Johnson, K.S.2
-
17
-
-
0028092997
-
Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoforms
-
Dong, L-M., C. Wilson, M. R. Wardell, T. Simmons, R. W. Mahley, K. H. Weisgraber, and D. A. Agard. 1994. Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoforms. J. Biol. Chem. 269: 22358-22365.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 22358-22365
-
-
Dong, L.-M.1
Wilson, C.2
Wardell, M.R.3
Simmons, T.4
Mahley, R.W.5
Weisgraber, K.H.6
Agard, D.A.7
-
20
-
-
0018166663
-
Apoprotein (E-A-II) complex of human plasma lipoproteins. II. Receptor binding activity of a high density lipoprotein subfraction modulated by the apo(E-A-II) complex
-
Innerarity, T. L., R. W. Mahley, K. H. Weisgraber, and T. P. Bersot. 1978. Apoprotein (E-A-II) complex of human plasma lipoproteins. II. Receptor binding activity of a high density lipoprotein subfraction modulated by the apo(E-A-II) complex. J. Biol. Chem. 253: 6289-6295.
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 6289-6295
-
-
Innerarity, T.L.1
Mahley, R.W.2
Weisgraber, K.H.3
Bersot, T.P.4
-
21
-
-
0015518106
-
The metabolism of very low density lipoprotein proteins. I. Preliminary in vitro and in vivo observations
-
Bilheimer, D. W., S. Eisenberg, and R. I. Levy. 1972. The metabolism of very low density lipoprotein proteins. I. Preliminary in vitro and in vivo observations. Biochim. Biophys. Acta. 260: 212-221.
-
(1972)
Biochim. Biophys. Acta
, vol.260
, pp. 212-221
-
-
Bilheimer, D.W.1
Eisenberg, S.2
Levy, R.I.3
-
22
-
-
0018800929
-
Binding of arginine-rich (E) apoprotein after recombination with phospholipid vesicles to the low density lipoprotein receptors of fibroblasts
-
Innerarity, T. L., R. E. Pitas, and R. W. Mahley. 1979. Binding of arginine-rich (E) apoprotein after recombination with phospholipid vesicles to the low density lipoprotein receptors of fibroblasts. J. Biol. Chem. 254: 4186-4190.
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 4186-4190
-
-
Innerarity, T.L.1
Pitas, R.E.2
Mahley, R.W.3
-
23
-
-
0023664025
-
Synthetic high density lipoprotein particles. Application to studies of the apoprotein specificity for selective uptake of cholesterol esters
-
Pittman, R. C., C. K. Glass, D. Atkinson, and D. M. Small. 1987. Synthetic high density lipoprotein particles. Application to studies of the apoprotein specificity for selective uptake of cholesterol esters. J. Biol. Chem. 262: 2435-2442.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 2435-2442
-
-
Pittman, R.C.1
Glass, C.K.2
Atkinson, D.3
Small, D.M.4
-
24
-
-
0023853881
-
The ionization and distribution behavior of oleic acid in chylomicrons and chylomicron-like emulsion particles and the influence of serum albumin
-
Spooner, P. J. R., S. B. Clark, D. L. Gantz, J. A. Hamilton, and D. M. Small. 1988. The ionization and distribution behavior of oleic acid in chylomicrons and chylomicron-like emulsion particles and the influence of serum albumin. J. Biol. Chem. 263: 1444-1453.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 1444-1453
-
-
Spooner, P.J.R.1
Clark, S.B.2
Gantz, D.L.3
Hamilton, J.A.4
Small, D.M.5
-
25
-
-
0028850374
-
Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth
-
Bellosta, S., B. P. Nathan, M. Orth, L-M. Dong, R. W. Mahley, and R. E. Pitas. 1995. Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth. J. Biol. Chem. 270: 27063-27071.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27063-27071
-
-
Bellosta, S.1
Nathan, B.P.2
Orth, M.3
Dong, L.-M.4
Mahley, R.W.5
Pitas, R.E.6
-
26
-
-
0030830186
-
Human low density lipoprotein fragment successful refolding of a functionally active ligand-binding domain produced in Escherichia coli
-
Simmons, T., Y. M. Newhouse, K. S. Arnold, T. L. Innerarity, and K. H. Weisgraber. 1997. Human low density lipoprotein fragment successful refolding of a functionally active ligand-binding domain produced in Escherichia coli. J. Biol. Chem. 272: 25531-25536.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25531-25536
-
-
Simmons, T.1
Newhouse, Y.M.2
Arnold, K.S.3
Innerarity, T.L.4
Weisgraber, K.H.5
-
27
-
-
0019321262
-
Cell surface receptor binding of phospholipid-protein complexes containing different ratios of receptor-active and -inactive E apoprotein
-
Pitas, R. E., T. L. Innerarity, and R. W. Mahley. 1980. Cell surface receptor binding of phospholipid-protein complexes containing different ratios of receptor-active and -inactive E apoprotein. J. Biol. Chem. 255: 5454-5460.
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 5454-5460
-
-
Pitas, R.E.1
Innerarity, T.L.2
Mahley, R.W.3
-
28
-
-
0027186135
-
Discrete carboxyl-terminal segments of apolipoprotein E mediate lipoprotein association and protein oligomerization
-
Westerlund, J. A., and K. H. Weisgraber. 1993. Discrete carboxyl-terminal segments of apolipoprotein E mediate lipoprotein association and protein oligomerization. J. Biol. Chem. 268: 15745-15750.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15745-15750
-
-
Westerlund, J.A.1
Weisgraber, K.H.2
-
29
-
-
0027528427
-
Preferential association of apolipoprotein E Leiden with very low density lipoproteins of human plasma
-
Fazio, S., Y. Horie, K. H. Weisgraber, L. M. Havekes, and S. C. Rall, Jr. 1993. Preferential association of apolipoprotein E Leiden with very low density lipoproteins of human plasma. J. Lipid Res. 34: 447-453.
-
(1993)
J. Lipid Res.
, vol.34
, pp. 447-453
-
-
Fazio, S.1
Horie, Y.2
Weisgraber, K.H.3
Havekes, L.M.4
Rall Jr., S.C.5
-
30
-
-
0029766916
-
Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins
-
Dong, L-M., and K. H. Weisgraber. 1996. Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins. J. Biol Chem. 271: 19053-19057.
-
(1996)
J. Biol Chem.
, vol.271
, pp. 19053-19057
-
-
Dong, L.-M.1
Weisgraber, K.H.2
-
31
-
-
0026584011
-
The functional characteristics of a human apolipoprotein e variant (cysteine at residue 142) may explain its association with dominant expression of type III hyperlipoproteinemia
-
Horie, Y., S. Fazio, J. R. Westerlund, K. H. Weisgraber, and S. C. Rall, Jr. 1992. The functional characteristics of a human apolipoprotein E variant (cysteine at residue 142) may explain its association with dominant expression of type III hyperlipoproteinemia. J. Biol. Chem. 267: 1962-1968.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 1962-1968
-
-
Horie, Y.1
Fazio, S.2
Westerlund, J.R.3
Weisgraber, K.H.4
Rall Jr., S.C.5
-
32
-
-
0022963784
-
Type III hyperlipoproteinemia: A focus on lipoprotein receptor-apolipoprotein E2 interactions
-
Innerarity, T. L., D. Y Hui, T. P. Bersot, and R. W. Mahley. 1986. Type III hyperlipoproteinemia: a focus on lipoprotein receptor-apolipoprotein E2 interactions. Adv. Exp. Med. Biol. 201: 273-288.
-
(1986)
Adv. Exp. Med. Biol.
, vol.201
, pp. 273-288
-
-
Innerarity, T.L.1
Hui, D.Y.2
Bersot, T.P.3
Mahley, R.W.4
-
33
-
-
0025860481
-
Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E
-
Wilson, C., M. R. Wardell, K. H. Weisgraber, R. W. Mahley, and D. A. Agard. 1991. Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E. Science. 252:1817-1822.
-
(1991)
Science
, vol.252
, pp. 1817-1822
-
-
Wilson, C.1
Wardell, M.R.2
Weisgraber, K.H.3
Mahley, R.W.4
Agard, D.A.5
|