Mutational analysis of the active site of indoleglycerol phosphate synthase from Escherichia coli

Protein Science

Volumn 7, Issue 5, 1998, Pages 1221-1232

  Darimont, Beatrice ^a,b   Stehlin, Catherine ^a,c   Szadkowski, Halina ^a   Kirschner, Kasper ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INSTITUT LAUE LANGEVIN   (France)

Author keywords

( )8 barrel proteins; Catalytic mechanism; Complementation; IGP synthase, random mutation; Tryptophan biosynthesis

Indexed keywords

ALANINE; ASPARTIC ACID; CHORISMIC ACID; CYSTEINE; GLYCEROPHOSPHATE; INDOLE DERIVATIVE; MUTANT PROTEIN; RIBULOSE PHOSPHATE; SOLVENT; SYNTHETASE; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME INHIBITOR INTERACTION; ENZYME KINETICS; ESCHERICHIA COLI; GENE DELETION; GENETIC COMPLEMENTATION; MUTAGENESIS; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0031863441     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1002/pro.5560070518     Document Type: Article

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