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Volumn 9, Issue 2-3, 1998, Pages 83-87

Novel anticoagulants based on inhibition of the factor VIIa/tissue factor pathway

Author keywords

Antibodies; Coagulation; Factor VII; Inflammation; Nematode anticoagulant protein c2; Sepsis; Tissue factor; Tissue factor pathway inhibitor

Indexed keywords

ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 7A; NEW DRUG; THROMBOPLASTIN;

EID: 0031862826     PISSN: 09546928     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019501-199809020-00004     Document Type: Review
Times cited : (13)

References (75)
  • 1
    • 0026337077 scopus 로고
    • The coagulation cascade: Initiation, maintenance, and regulation
    • Davie EW, Fujikawa K, Kisiel W. The coagulation cascade: initiation, maintenance, and regulation. Biochemistry 1991, 30:10363-10370.
    • (1991) Biochemistry , vol.30 , pp. 10363-10370
    • Davie, E.W.1    Fujikawa, K.2    Kisiel, W.3
  • 2
    • 0026764143 scopus 로고
    • The role of tissue factor pathway inhibitor in a revised coagulation cascade
    • Broze GJ Jr. The role of tissue factor pathway inhibitor in a revised coagulation cascade. Semin Hematol 1992, 29:159-169.
    • (1992) Semin Hematol , vol.29 , pp. 159-169
    • Broze Jr., G.J.1
  • 3
    • 0013879315 scopus 로고
    • The reaction between bovine brain tissue factor and factors VII and X
    • Nemerson Y. The reaction between bovine brain tissue factor and factors VII and X. Biochemistry 1966, 5:601-608.
    • (1966) Biochemistry , vol.5 , pp. 601-608
    • Nemerson, Y.1
  • 4
    • 0017639138 scopus 로고
    • Activation of factor IX by the reaction product of tissue factor and factor VII: Additional pathway for initiating blood coagulation
    • Osterud B, Rapaport SI. Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation. Proc Natl Acad Sci USA 1977, 74: 5260-5264.
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 5260-5264
    • Osterud, B.1    Rapaport, S.I.2
  • 5
    • 0030746633 scopus 로고    scopus 로고
    • Tissue factor: A complex biological role
    • Osterud B. Tissue factor: a complex biological role. Thromb Haemost 1997 78:755-758.
    • (1997) Thromb Haemost , vol.78 , pp. 755-758
    • Osterud, B.1
  • 6
    • 0023812085 scopus 로고
    • Monoclonal antibody analysis of purified and cell-associated tissue factor
    • Morrissey JH, Fair DS, Edgington TS. Monoclonal antibody analysis of purified and cell-associated tissue factor. Thromb Res 1988, 52:247-261.
    • (1988) Thromb Res , vol.52 , pp. 247-261
    • Morrissey, J.H.1    Fair, D.S.2    Edgington, T.S.3
  • 7
    • 0025904459 scopus 로고
    • Lethal E. coli septic shock is prevented by blocking tissue factor with monoclonal antibody
    • Taylor FB Jr, Chang A, Ruf W, Morrissey JH, Hinshaw L, Catlett R, et al. Lethal E. coli septic shock is prevented by blocking tissue factor with monoclonal antibody. Circ Shock 1991, 33:127-134.
    • (1991) Circ Shock , vol.33 , pp. 127-134
    • Taylor Jr., F.B.1    Chang, A.2    Ruf, W.3    Morrissey, J.H.4    Hinshaw, L.5    Catlett, R.6
  • 8
    • 0030917536 scopus 로고    scopus 로고
    • A soluble tissue factor mutant is a selective anticoagulant and antithrombotic agent
    • Kelley RF, Refino CJ, O'Connell MP, Modi N, Sehl P, Lowe D, et al. A soluble tissue factor mutant is a selective anticoagulant and antithrombotic agent. Blood 1997, 89:3219-3227.
    • (1997) Blood , vol.89 , pp. 3219-3227
    • Kelley, R.F.1    Refino, C.J.2    O'Connell, M.P.3    Modi, N.4    Sehl, P.5    Lowe, D.6
  • 9
    • 0028822695 scopus 로고
    • A peptide derived from a tissue factor loop region functions as a tissue factor-factor VIIa antagonist
    • Paborsky LR, Law VS, Mao CT, Leung LL, Gibbs CS. A peptide derived from a tissue factor loop region functions as a tissue factor-factor VIIa antagonist. Biochemistry 1995, 34:15328-15333.
    • (1995) Biochemistry , vol.34 , pp. 15328-15333
    • Paborsky, L.R.1    Law, V.S.2    Mao, C.T.3    Leung, L.L.4    Gibbs, C.S.5
  • 10
    • 0030588161 scopus 로고    scopus 로고
    • Synthetic peptide analogs of tissue factor and factor VII which inhibit factor Xa formation by the tissue factor/factor VIIa complex
    • Ronning HF, Risoen UC, Orning L, Sletten K, Sakariassen KS. Synthetic peptide analogs of tissue factor and factor VII which inhibit factor Xa formation by the tissue factor/factor VIIa complex. Thromb Res 1996, 84:73-81.
    • (1996) Thromb Res , vol.84 , pp. 73-81
    • Ronning, H.F.1    Risoen, U.C.2    Orning, L.3    Sletten, K.4    Sakariassen, K.S.5
  • 11
    • 0030805621 scopus 로고    scopus 로고
    • The factor VIIa/tissue factor complex
    • Banner DW. The factor VIIa/tissue factor complex. Thromb Haemost 1997, 78:512-515.
    • (1997) Thromb Haemost , vol.78 , pp. 512-515
    • Banner, D.W.1
  • 12
    • 0028895452 scopus 로고
    • Complete inhibition of endotoxin-induced coagulation activation in chimpanzees with a monoclonal Fab fragment against factor VII/VIIa
    • Biemond BJ, Levi M, ten Cate H, Soule HR, Morris LD, Foster DL. Complete inhibition of endotoxin-induced coagulation activation in chimpanzees with a monoclonal Fab fragment against factor VII/VIIa. Thromb Haemost 1995, 73:223-230.
    • (1995) Thromb Haemost , vol.73 , pp. 223-230
    • Biemond, B.J.1    Levi, M.2    Ten Cate, H.3    Soule, H.R.4    Morris, L.D.5    Foster, D.L.6
  • 13
    • 0029912586 scopus 로고    scopus 로고
    • Role of tissue factor and factor VIIa in the coagulant and inflammatory response to LD100 Escherichia coli in the baboon
    • Taylor FB Jr. Role of tissue factor and factor VIIa in the coagulant and inflammatory response to LD100 Escherichia coli in the baboon. Haemostasis 1996, 26 (suppl 1):83-91.
    • (1996) Haemostasis , vol.26 , Issue.1 SUPPL. , pp. 83-91
    • Taylor Jr., F.B.1
  • 14
    • 0029984412 scopus 로고    scopus 로고
    • Antithrombotic and antilesion benefits without hemorrhagic risks by inhibiting tissue factor pathway
    • Harker LA, Hanson SR, Wilcox JN, Kelly AB. Antithrombotic and antilesion benefits without hemorrhagic risks by inhibiting tissue factor pathway. Haemostasis 1996, 26 (suppl 1):76-82.
    • (1996) Haemostasis , vol.26 , Issue.1 SUPPL. , pp. 76-82
    • Harker, L.A.1    Hanson, S.R.2    Wilcox, J.N.3    Kelly, A.B.4
  • 15
    • 0028839499 scopus 로고
    • Influence of blockade at specific levels of the coagulation cascade on restenosis in a rabbit atherosclerotic femoral artery injury model
    • Jang Y, Guzman LA, Lincoff AM, Gottsauner-Wolf M, Forudi F, Hart CE, et al. Influence of blockade at specific levels of the coagulation cascade on restenosis in a rabbit atherosclerotic femoral artery injury model. Circulation 1995, 92:3041-3050.
    • (1995) Circulation , vol.92 , pp. 3041-3050
    • Jang, Y.1    Guzman, L.A.2    Lincoff, A.M.3    Gottsauner-Wolf, M.4    Forudi, F.5    Hart, C.E.6
  • 16
    • 0031058380 scopus 로고    scopus 로고
    • Prevention of experimental arterial thrombosis by topical administration of active site-inactivated factor VIIa
    • Arnljots B, Ezban M, Hedner U. Prevention of experimental arterial thrombosis by topical administration of active site-inactivated factor VIIa. J Vasc Surg 1997. 25:341-346.
    • (1997) J Vasc Surg , vol.25 , pp. 341-346
    • Arnljots, B.1    Ezban, M.2    Hedner, U.3
  • 17
    • 0030991982 scopus 로고    scopus 로고
    • Incorporation of an active site inhibitor in factor VIIa alters the affinity for tissue factor
    • Sorensen BB, Persson E, Freskgard PO, Kjalke M, Ezban M, Williams T, et al. Incorporation of an active site inhibitor in factor VIIa alters the affinity for tissue factor. J Biol Chem 1997, 272:11863-11868.
    • (1997) J Biol Chem , vol.272 , pp. 11863-11868
    • Sorensen, B.B.1    Persson, E.2    Freskgard, P.O.3    Kjalke, M.4    Ezban, M.5    Williams, T.6
  • 18
    • 0029082791 scopus 로고
    • Tissue factor pathway inhibitor
    • Broze GJ Jr. Tissue factor pathway inhibitor. Thromb Haemost 1995, 74:90-93.
    • (1995) Thromb Haemost , vol.74 , pp. 90-93
    • Broze Jr., G.J.1
  • 19
    • 0029153045 scopus 로고
    • The tissue factor pathway: How it has become a 'prima ballerina'
    • Rapaport SI, Rao LV. The tissue factor pathway: how it has become a 'prima ballerina'. Thromb Haemost 1995, 74:7-17.
    • (1995) Thromb Haemost , vol.74 , pp. 7-17
    • Rapaport, S.I.1    Rao, L.V.2
  • 20
    • 0029853894 scopus 로고    scopus 로고
    • Tissue factor pathway inhibitor (TFPI)-an update
    • Sandset PM. Tissue factor pathway inhibitor (TFPI)-an update. Haemostasis 1996, 26 (suppl 4):154-165.
    • (1996) Haemostasis , vol.26 , Issue.4 SUPPL. , pp. 154-165
    • Sandset, P.M.1
  • 21
    • 0030738021 scopus 로고    scopus 로고
    • Tissue factor pathway inhibitor gene disruption produces intrauterine lethality in mice
    • Huang ZF, Higuchi D, Lasky N, Broze GJ Jr. Tissue factor pathway inhibitor gene disruption produces intrauterine lethality in mice. Blood 1997, 90:944-951.
    • (1997) Blood , vol.90 , pp. 944-951
    • Huang, Z.F.1    Higuchi, D.2    Lasky, N.3    Broze Jr., G.J.4
  • 22
    • 0023924263 scopus 로고
    • Cloning and characterization of a cDNA coding for the lipoprotein-associated coagulation inhibitor shows that it consists of three tandem Kunitz-type inhibitory domains
    • Wun TC, Kretzmer KK, Girard TJ, Miletich JP, Broze GJ Jr. Cloning and characterization of a cDNA coding for the lipoprotein-associated coagulation inhibitor shows that it consists of three tandem Kunitz-type inhibitory domains. J Biol Chem 1988, 263:6001-6004.
    • (1988) J Biol Chem , vol.263 , pp. 6001-6004
    • Wun, T.C.1    Kretzmer, K.K.2    Girard, T.J.3    Miletich, J.P.4    Broze Jr., G.J.5
  • 23
    • 0023851665 scopus 로고
    • The lipoprotein-associated coagulation inhibitor that inhibits the factor VII-tissue factor complex also inhibits factor Xa: Insight into its possible mechanism of action
    • Broze GJ Jr, Warren LA, Novotny WF, Higuchi DA, Girard JJ, Miletich JP. The lipoprotein-associated coagulation inhibitor that inhibits the factor VII-tissue factor complex also inhibits factor Xa: insight into its possible mechanism of action. Blood 1988, 71:335-343.
    • (1988) Blood , vol.71 , pp. 335-343
    • Broze Jr., G.J.1    Warren, L.A.2    Novotny, W.F.3    Higuchi, D.A.4    Girard, J.J.5    Miletich, J.P.6
  • 24
    • 0024543984 scopus 로고
    • Functional significance of the Kunitz-type inhibitory domains of lipoprotein-associated coagulation inhibitor
    • Girard TJ, Warren LA, Novotny WF, Likert KM, Brown SG, Miletich JP, et al. Functional significance of the Kunitz-type inhibitory domains of lipoprotein-associated coagulation inhibitor. Nature 1989, 338:518-520.
    • (1989) Nature , vol.338 , pp. 518-520
    • Girard, T.J.1    Warren, L.A.2    Novotny, W.F.3    Likert, K.M.4    Brown, S.G.5    Miletich, J.P.6
  • 25
    • 0026668480 scopus 로고
    • Tissue factor pathway inhibitor: The carboxy-terminus is required for optimal inhibition of factor Xa
    • Wesselschmidt R, Likert K, Girard T, Wun TC, Broze GJ Jr. Tissue factor pathway inhibitor: the carboxy-terminus is required for optimal inhibition of factor Xa. Blood 1992, 79:2004-2010.
    • (1992) Blood , vol.79 , pp. 2004-2010
    • Wesselschmidt, R.1    Likert, K.2    Girard, T.3    Wun, T.C.4    Broze Jr., G.J.5
  • 26
    • 0025871461 scopus 로고
    • Purification and properties of heparin-releasable lipoprotein-associated coagulation inhibitor
    • Novotny WF, Palmier M, Wun TC, Broze GJ Jr, Miletich JP. Purification and properties of heparin-releasable lipoprotein-associated coagulation inhibitor. Blood 1991, 78:394-400.
    • (1991) Blood , vol.78 , pp. 394-400
    • Novotny, W.F.1    Palmier, M.2    Wun, T.C.3    Broze Jr., G.J.4    Miletich, J.P.5
  • 27
    • 0029004209 scopus 로고
    • Effect of heparin on the inhibition of factor Xa by tissue factor pathway inhibitor: A segment, Gly212-Phe243, of the third Kunitz domain is a heparin-binding site
    • Enjyoji K, Miyata T, Kamikubo Y, Kato H. Effect of heparin on the inhibition of factor Xa by tissue factor pathway inhibitor: a segment, Gly212-Phe243, of the third Kunitz domain is a heparin-binding site. Biochemistry 1995, 34:5725-5735.
    • (1995) Biochemistry , vol.34 , pp. 5725-5735
    • Enjyoji, K.1    Miyata, T.2    Kamikubo, Y.3    Kato, H.4
  • 28
    • 0024434125 scopus 로고
    • Purification and characterization of the lipoprotein-associated coagulation inhibitor from human plasma
    • Novotny WF, Girard TJ, Miletich JP, Broze GJ Jr. Purification and characterization of the lipoprotein-associated coagulation inhibitor from human plasma. J Biol Chem 1989, 264:18832-18837.
    • (1989) J Biol Chem , vol.264 , pp. 18832-18837
    • Novotny, W.F.1    Girard, T.J.2    Miletich, J.P.3    Broze Jr., G.J.4
  • 30
    • 0027424985 scopus 로고
    • Characterization of human tissue factor pathway inhibitor variants expressed in Saccharomyces cerevisiae
    • Petersen JG, Meyn G, Rasmussen JS, Petersen J, Bjorn SE, Jonassen I, et al. Characterization of human tissue factor pathway inhibitor variants expressed in Saccharomyces cerevisiae. J Biol Chem 1993, 268:13344-13351.
    • (1993) J Biol Chem , vol.268 , pp. 13344-13351
    • Petersen, J.G.1    Meyn, G.2    Rasmussen, J.S.3    Petersen, J.4    Bjorn, S.E.5    Jonassen, I.6
  • 31
    • 0030745177 scopus 로고    scopus 로고
    • Tissue factor pathway inhibitor: Potential therapeutic applications
    • Bajaj MS, Bajaj SP. Tissue factor pathway inhibitor: potential therapeutic applications. Thromb Haemost 1997, 78:471-477.
    • (1997) Thromb Haemost , vol.78 , pp. 471-477
    • Bajaj, M.S.1    Bajaj, S.P.2
  • 33
    • 0030027273 scopus 로고    scopus 로고
    • Prevention of microvascular thrombosis by topical application of recombinant tissue factor pathway inhibitor
    • Lantieri LA, Ozbek MR, Deune EG, Ornberg RL, Brown DM, Chung SH, et al. Prevention of microvascular thrombosis by topical application of recombinant tissue factor pathway inhibitor. Plast Reconstr Surg 1996, 97:587-594.
    • (1996) Plast Reconstr Surg , vol.97 , pp. 587-594
    • Lantieri, L.A.1    Ozbek, M.R.2    Deune, E.G.3    Ornberg, R.L.4    Brown, D.M.5    Chung, S.H.6
  • 35
    • 0028627767 scopus 로고
    • Recombinant E. coli-derived tissue factor pathway inhibitor reduces coagulopathic and lethal effects in the baboon Gram-negative model of septic shock
    • Carr C, Bild GS, Chang AC, Peer GT, Palmier MO, Frazier RB, et al. Recombinant E. coli-derived tissue factor pathway inhibitor reduces coagulopathic and lethal effects in the baboon Gram-negative model of septic shock. Circ Shock 1994, 44:126-137.
    • (1994) Circ Shock , vol.44 , pp. 126-137
    • Carr, C.1    Bild, G.S.2    Chang, A.C.3    Peer, G.T.4    Palmier, M.O.5    Frazier, R.B.6
  • 36
    • 0031934850 scopus 로고    scopus 로고
    • Delayed treatment with recombinant human tissue factor pathway inhibitor (TFPI) improves survival in rabbits with Gram-negative peritonitis
    • Camerota A, Creasey AA, Patla, V, Larkin V, Fink M. Delayed treatment with recombinant human tissue factor pathway inhibitor (TFPI) improves survival in rabbits with Gram-negative peritonitis. J Infect Dis 1998, 177:668-676.
    • (1998) J Infect Dis , vol.177 , pp. 668-676
    • Camerota, A.1    Creasey, A.A.2    Patla, V.3    Larkin, V.4    Fink, M.5
  • 37
    • 0027435928 scopus 로고
    • The effect of two-domain tissue factor pathway inhibitor on endotoxin-induced disseminated intravascular coagulation in rabbits
    • Bregengard C, Nordfang O, Wildgoose P, Svendsen O, Hedner U, Diness V. The effect of two-domain tissue factor pathway inhibitor on endotoxin-induced disseminated intravascular coagulation in rabbits. Blood Coagul Fibrinolysis 1993, 4:699-706.
    • (1993) Blood Coagul Fibrinolysis , vol.4 , pp. 699-706
    • Bregengard, C.1    Nordfang, O.2    Wildgoose, P.3    Svendsen, O.4    Hedner, U.5    Diness, V.6
  • 39
    • 0030752525 scopus 로고    scopus 로고
    • Inhibition of tissue factor-mediated coagulation markedly attenuates stenosis after balloon-induced arterial injury in minipigs
    • Oltrona L, Speidel CM, Recchia D, Wickline SA, Eisenberg PR, Abendschein DR. Inhibition of tissue factor-mediated coagulation markedly attenuates stenosis after balloon-induced arterial injury in minipigs. Circulation 1997, 96:646-652.
    • (1997) Circulation , vol.96 , pp. 646-652
    • Oltrona, L.1    Speidel, C.M.2    Recchia, D.3    Wickline, S.A.4    Eisenberg, P.R.5    Abendschein, D.R.6
  • 40
    • 14444278775 scopus 로고    scopus 로고
    • Local delivery of tissue factor pathway inhibitor (TFPI) to reduce neointimal proliferation in the porcine coronary balloon injury model
    • Steinhubl SR, Belli G, Wu C, Yoon J, Furst J, Gallupi GR, et al. Local delivery of tissue factor pathway inhibitor (TFPI) to reduce neointimal proliferation in the porcine coronary balloon injury model. J Am Coll Cardiol 1997, 29 (suppl A): 243A.
    • (1997) J Am Coll Cardiol , vol.29 , Issue.SUPPL. A
    • Steinhubl, S.R.1    Belli, G.2    Wu, C.3    Yoon, J.4    Furst, J.5    Gallupi, G.R.6
  • 41
    • 0030799201 scopus 로고    scopus 로고
    • Tissue factor pathway inhibitor inhibits aortic smooth muscle cell migration induced by tissue factor/factor VIIa complex
    • Sato Y, Asada Y, Marutsuka K, Hatakeyama K, Kamikubo Y, Sumiyoshi A. Tissue factor pathway inhibitor inhibits aortic smooth muscle cell migration induced by tissue factor/factor VIIa complex. Thromb Haemost 1997, 78:1138-1141.
    • (1997) Thromb Haemost , vol.78 , pp. 1138-1141
    • Sato, Y.1    Asada, Y.2    Marutsuka, K.3    Hatakeyama, K.4    Kamikubo, Y.5    Sumiyoshi, A.6
  • 42
    • 0030036852 scopus 로고    scopus 로고
    • Renal expression of tissue factor pathway inhibitor and evidence for a role in crescentic glomerulonephritis in rabbits
    • Erlich JH, Apostolopoulos J, Wun TC, Kretzmer KK, Holdsworth SR, Tipping PG. Renal expression of tissue factor pathway inhibitor and evidence for a role in crescentic glomerulonephritis in rabbits. J Clin Invest 1996, 98:325-335.
    • (1996) J Clin Invest , vol.98 , pp. 325-335
    • Erlich, J.H.1    Apostolopoulos, J.2    Wun, T.C.3    Kretzmer, K.K.4    Holdsworth, S.R.5    Tipping, P.G.6
  • 44
    • 14444277048 scopus 로고    scopus 로고
    • Comparison of nematode anticoagulant proteins (NAPs) with low molecular weight heparin in a model of disseminated intravascular coagulation (DIC)
    • Berkeley C, Rote W. Comparison of nematode anticoagulant proteins (NAPs) with low molecular weight heparin in a model of disseminated intravascular coagulation (DIC). Circulation 1996, 94 (suppl 8):I696.
    • (1996) Circulation , vol.94 , Issue.8 SUPPL.
    • Berkeley, C.1    Rote, W.2
  • 45
    • 0028085530 scopus 로고
    • Kunitz domain inhibitors of tissue factor-factor VIIa. I. Potent inhibitors selected from libraries by phage display
    • Dennis MS, Lazarus RA. Kunitz domain inhibitors of tissue factor-factor VIIa. I. Potent inhibitors selected from libraries by phage display. J Biol Chem 1994, 269:22129-22136.
    • (1994) J Biol Chem , vol.269 , pp. 22129-22136
    • Dennis, M.S.1    Lazarus, R.A.2
  • 46
    • 4243664184 scopus 로고
    • Evaluation of novel anticoagulants in a rabbit arterial thrombosis model
    • Refino C, Pater C, Wu D, Lazarus R, Dinnis M, Kelley R, et al. Evaluation of novel anticoagulants in a rabbit arterial thrombosis model. Blood 1995, 86 (suppl 1): 90a.
    • (1995) Blood , vol.86 , Issue.1 SUPPL.
    • Refino, C.1    Pater, C.2    Wu, D.3    Lazarus, R.4    Dinnis, M.5    Kelley, R.6
  • 47
    • 0030035480 scopus 로고    scopus 로고
    • Antithrombin-mediated inhibition of factor VIIa-tissue factor complex by the synthetic pentasaccharide representing the heparin binding site to antithrombin
    • Lormeau JC, Herault JP, Herbert JM. Antithrombin-mediated inhibition of factor VIIa-tissue factor complex by the synthetic pentasaccharide representing the heparin binding site to antithrombin. Thromb Haemost 1996, 76:5-8.
    • (1996) Thromb Haemost , vol.76 , pp. 5-8
    • Lormeau, J.C.1    Herault, J.P.2    Herbert, J.M.3
  • 48
    • 0028896007 scopus 로고
    • Mechanism of antithrombin III inhibition of factor VIIa/tissue factor activity on cell surfaces. Comparison with tissue factor pathway inhibitor/factor Xa-induced inhibition of factor VIIa/tissue factor activity
    • Rao LV, Nordfang O, Hoang AD, Pendurthi UR. Mechanism of antithrombin III inhibition of factor VIIa/tissue factor activity on cell surfaces. Comparison with tissue factor pathway inhibitor/factor Xa-induced inhibition of factor VIIa/tissue factor activity. Blood 1995, 85:121-129.
    • (1995) Blood , vol.85 , pp. 121-129
    • Rao, L.V.1    Nordfang, O.2    Hoang, A.D.3    Pendurthi, U.R.4
  • 49
    • 0029095017 scopus 로고
    • Xa receptor EPR-1
    • Altieri DC. Xa receptor EPR-1. FASEB J 1995, 9:860-865.
    • (1995) FASEB J , vol.9 , pp. 860-865
    • Altieri, D.C.1
  • 51
    • 0026766175 scopus 로고
    • Modulators of coagulation. A critical appraisal of their role in sepsis
    • Bone RC. Modulators of coagulation. A critical appraisal of their role in sepsis. Arch Intern Med 1992, 152:1381-1389.
    • (1992) Arch Intern Med , vol.152 , pp. 1381-1389
    • Bone, R.C.1
  • 52
    • 0027424531 scopus 로고
    • Cell mediated events that control blood coagulation and vascular injury
    • Esmon CT. Cell mediated events that control blood coagulation and vascular injury. Annu Rev Cell Biol 1993, 9:1-26.
    • (1993) Annu Rev Cell Biol , vol.9 , pp. 1-26
    • Esmon, C.T.1
  • 53
    • 0021199320 scopus 로고
    • Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells
    • Bevilacqua MP, Pober JS, Majeau GR, Cotran RS, Gimbrone MA Jr. Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells. J Exp Med 1984, 160:618-623.
    • (1984) J Exp Med , vol.160 , pp. 618-623
    • Bevilacqua, M.P.1    Pober, J.S.2    Majeau, G.R.3    Cotran, R.S.4    Gimbrone Jr., M.A.5
  • 54
    • 0000555820 scopus 로고
    • Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: Characterization and comparison with the actions of interleukin 1
    • Bevilacqua MP, Pober JS, Majeau GR, Fiers W, Cotran RS, Gimbrone MA Jr. Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1. Proc Natl Acad Sci USA 1986, 83:4533-4537.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 4533-4537
    • Bevilacqua, M.P.1    Pober, J.S.2    Majeau, G.R.3    Fiers, W.4    Cotran, R.S.5    Gimbrone Jr., M.A.6
  • 55
    • 0015247178 scopus 로고
    • The role of Hageman factor in disseminated intravascular coagulation induced by septicemia, neoplasia, or liver disease
    • Mason JW, Colman RW. The role of Hageman factor in disseminated intravascular coagulation induced by septicemia, neoplasia, or liver disease. Thromb Diath Haemorrh 1971, 26:325-331.
    • (1971) Thromb Diath Haemorrh , vol.26 , pp. 325-331
    • Mason, J.W.1    Colman, R.W.2
  • 56
    • 0029986326 scopus 로고    scopus 로고
    • Inhibition of factor XII in septic baboons attenuates the activation of complement and fibrinolytic systems and reduces the release of interteukin-6 and neutrophil elastase
    • Jansen PM, Pixley RA, Brouwer M, de Jong IW, Chang AC, Hack CE, et al. Inhibition of factor XII in septic baboons attenuates the activation of complement and fibrinolytic systems and reduces the release of interteukin-6 and neutrophil elastase. Blood 1996, 87:2337-2344.
    • (1996) Blood , vol.87 , pp. 2337-2344
    • Jansen, P.M.1    Pixley, R.A.2    Brouwer, M.3    De Jong, I.W.4    Chang, A.C.5    Hack, C.E.6
  • 58
    • 0028965560 scopus 로고
    • 2+ signals in J82 cells, transfected COS-1 cells, Madin-Darby canine kidney cells and in human endothelial cells induced to synthesize tissue factor
    • 2+ signals in J82 cells, transfected COS-1 cells, Madin-Darby canine kidney cells and in human endothelial cells induced to synthesize tissue factor. J Biol Chem 1995, 270:4650-4660.
    • (1995) J Biol Chem , vol.270 , pp. 4650-4660
    • Rottingen, J.A.1    Enden, T.2    Camerer, E.3    Iversen, J.G.4    Prydz, H.5
  • 60
    • 0030995868 scopus 로고    scopus 로고
    • Factor Xa as an interface between coagulation and inflammation. Molecular mimicry of factor Xa association with effector cell protease receptor-1 induces acute inflammation in vivo
    • Cirino G, Cicala C, Bucci M, Sorrentino L, Ambrosini G, DeDominicis G, et al. Factor Xa as an interface between coagulation and inflammation. Molecular mimicry of factor Xa association with effector cell protease receptor-1 induces acute inflammation in vivo. J Clin Invest 1997, 99:2446-2451.
    • (1997) J Clin Invest , vol.99 , pp. 2446-2451
    • Cirino, G.1    Cicala, C.2    Bucci, M.3    Sorrentino, L.4    Ambrosini, G.5    DeDominicis, G.6
  • 61
    • 0029157318 scopus 로고
    • Proteases and protease receptors in modulation of leukocyte effector functions
    • Altieri DC. Proteases and protease receptors in modulation of leukocyte effector functions. J Leukoc Biol 1995, 58:120-127.
    • (1995) J Leukoc Biol , vol.58 , pp. 120-127
    • Altieri, D.C.1
  • 62
    • 14444269243 scopus 로고    scopus 로고
    • Factor Xa induction of a cytokine inflammatory response in vascular endothelim. Implication for a protease-activated signaling pathway
    • in press
    • Piccardoni P, Johnson K, Altieri D. Factor Xa induction of a cytokine inflammatory response in vascular endothelim. Implication for a protease-activated signaling pathway. Proc Natl Acad Sci USA 1998, (in press).
    • (1998) Proc Natl Acad Sci USA
    • Piccardoni, P.1    Johnson, K.2    Altieri, D.3
  • 63
    • 0025133268 scopus 로고
    • Thrombin and factor Xa enhance the production of interleukin-1
    • Jones, A, Geczy CL Thrombin and factor Xa enhance the production of interleukin-1. Immunology 1990, 71:236.
    • (1990) Immunology , vol.71 , pp. 236
    • Jones, A.1    Geczy, C.L.2
  • 65
    • 0028279039 scopus 로고
    • A novel biologie activity of thrombin: Stimulation of monocyte chemotactic protein production
    • Grandaliano G, Valente AJ, Abboud HE. A novel biologie activity of thrombin: stimulation of monocyte chemotactic protein production. J Exp Med 1994, 179:1737-1741.
    • (1994) J Exp Med , vol.179 , pp. 1737-1741
    • Grandaliano, G.1    Valente, A.J.2    Abboud, H.E.3
  • 66
    • 0029114764 scopus 로고
    • Thrombin induces GRO alpha/MGSA production in human umbilical vein endothelial cells
    • Murakami K, Ueno A, Yamanouchi K, Kondo T. Thrombin induces GRO alpha/MGSA production in human umbilical vein endothelial cells. Thromb Res 1995, 79:387-394.
    • (1995) Thromb Res , vol.79 , pp. 387-394
    • Murakami, K.1    Ueno, A.2    Yamanouchi, K.3    Kondo, T.4
  • 67
    • 0028785163 scopus 로고
    • Thrombin enhances monocyte secretion of tumor necrosis factor and interleukin-1 beta by two distinct mechanisms
    • Hoffman M, Cooper ST. Thrombin enhances monocyte secretion of tumor necrosis factor and interleukin-1 beta by two distinct mechanisms. Blood Cells Mol Dis 1995, 21:156-167.
    • (1995) Blood Cells Mol Dis , vol.21 , pp. 156-167
    • Hoffman, M.1    Cooper, S.T.2
  • 68
    • 0030036714 scopus 로고    scopus 로고
    • Thrombin potently stimulates cytokine production in human vascular smooth muscle cells but not in mononuclear phagocytes
    • Kranzhofer R, Clinton SK, Ishii K, Coughlin SR, Fenton JW 2nd, Libby P. Thrombin potently stimulates cytokine production in human vascular smooth muscle cells but not in mononuclear phagocytes. Circ Res 1996, 79:286-294.
    • (1996) Circ Res , vol.79 , pp. 286-294
    • Kranzhofer, R.1    Clinton, S.K.2    Ishii, K.3    Coughlin, S.R.4    Fenton II, J.W.5    Libby, P.6
  • 69
    • 0028222277 scopus 로고
    • Expression of monocyte chemotactic protein-1 by monocytes and endothelial cells exposed to thrombin
    • Colotta F, Sciacca FL, Sironi M, Luini W, Rabiet MJ, Mantovani A. Expression of monocyte chemotactic protein-1 by monocytes and endothelial cells exposed to thrombin. Am J Pathol 1994, 144:975-985.
    • (1994) Am J Pathol , vol.144 , pp. 975-985
    • Colotta, F.1    Sciacca, F.L.2    Sironi, M.3    Luini, W.4    Rabiet, M.J.5    Mantovani, A.6
  • 70
    • 0030004297 scopus 로고    scopus 로고
    • Thrombin stimulates production of interleukin-8 in human umbilical vein endothelial cells
    • Ueno A, Murakami K, Yamanouchi K, Watanabe M, Kondo T. Thrombin stimulates production of interleukin-8 in human umbilical vein endothelial cells. Immunology 1996, 88:76-81.
    • (1996) Immunology , vol.88 , pp. 76-81
    • Ueno, A.1    Murakami, K.2    Yamanouchi, K.3    Watanabe, M.4    Kondo, T.5
  • 73
    • 0029986326 scopus 로고    scopus 로고
    • Inhibition of factor XII in septic baboons attenuates the activation of complement and fibrinolytic systems and reduces the release of interleukin-6 and neutrophil elastase
    • Jansen PM, Pixley RA, Brouwer M, de Jong IW, Chang AC, Hack CE, et al. Inhibition of factor XII in septic baboons attenuates the activation of complement and fibrinolytic systems and reduces the release of interleukin-6 and neutrophil elastase. Blood 1996, 87:2337-2344.
    • (1996) Blood , vol.87 , pp. 2337-2344
    • Jansen, P.M.1    Pixley, R.A.2    Brouwer, M.3    De Jong, I.W.4    Chang, A.C.5    Hack, C.E.6
  • 74
    • 0029996796 scopus 로고    scopus 로고
    • The proinflammatory cytokine response to coagulation and endotoxin in whole blood
    • Johnson K, Aarden L, Choi Y, De Groot E, Creasey A. The proinflammatory cytokine response to coagulation and endotoxin in whole blood. Blood 1996, 87:5051-5060.
    • (1996) Blood , vol.87 , pp. 5051-5060
    • Johnson, K.1    Aarden, L.2    Choi, Y.3    De Groot, E.4    Creasey, A.5
  • 75
    • 0030926515 scopus 로고    scopus 로고
    • Tissue factor pathway inhibitor blocks cellular effects of endotoxin by binding to endotoxin and interfering with transfer to CD14
    • Park C, Creasey A, Wright, S. Tissue factor pathway inhibitor blocks cellular effects of endotoxin by binding to endotoxin and interfering with transfer to CD14. Blood 1997, 89:4268-4274.
    • (1997) Blood , vol.89 , pp. 4268-4274
    • Park, C.1    Creasey, A.2    Wright, S.3


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