Assessment of correlation between skin target site free drug concentration and the in vivo topical antiviral efficacy in hairless mice for (e)-5-(2-bromovinyl)-2'-deoxyuridine and acyclovir formulations

Journal of Pharmaceutical Sciences

Volumn 87, Issue 8, 1998, Pages 917-922

  Afouna, Mohsen I ^a   Mehta, Samir C ^a,b   Ghanem, Abdel Halim ^a   Higuchi, William I ^a   Kern, Earl R ^a,c   De Clercq, Erik ^a,d   El Shahawy, Hamed H ^a,e  

^a UNIVERSITY OF UTAH   (United States)

^b GLAXOSMITHKLINE   (United States)

^c University of Alabama at Birmingham   (United States)

^d REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^e Al Azhar University   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

5 (2 BROMOVINYL) 2' DEOXYURIDINE; ACICLOVIR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG EFFICACY; DRUG FORMULATION; DRUG MECHANISM; DRUG TARGETING; INOCULATION; MOUSE; NONHUMAN; RISK ASSESSMENT; SKIN ABSORPTION; SKIN PENETRATION; TARGET CELL; TOPICAL DRUG ADMINISTRATION;

EID: 0031854840     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js980052a     Document Type: Article

References (20)

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