Correlation of in vivo topical efficacies with in vitro predictions using acyclovir formulations in the treatment of cutaneous HSV-1 infections in hairless mice: An evaluation of the predictive value of the C* concept

Antiviral Research

Volumn 29, Issue 2-3, 1996, Pages 279-286

  Patel, Phenil J ^a,b   Ghanem, Abdel Halim ^a   Higuchi, William I ^a   Srinivasan, V ^b   Kern, Earl R ^c  

^a UNIVERSITY OF UTAH   (United States)

^b TheraTech Inc   (United States)

^c UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

Author keywords

Acyclovir; Animal model; C* concept; HSV 1; Topical antiviral efficacies

Indexed keywords

ANIMALIA; HERPES; HUMAN HERPESVIRUS 1;

ACICLOVIR; ALCOHOL; DODECYL SULFATE SODIUM; LAURIC ACID METHYL ESTER; LAURYL PYRROLIDINE; MACROGOL; PENETRATION ENHANCING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; BASAL CELL; CONTROLLED STUDY; CORRELATION FUNCTION; DRUG CONCENTRATION; DRUG EFFICACY; DRUG FORMULATION; EPIDERMIS; FEMALE; HERPES SIMPLEX VIRUS 1; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; SKIN INFECTION; SKIN PENETRATION; TOPICAL DRUG ADMINISTRATION;

ACYCLOVIR; ADMINISTRATION, TOPICAL; ANIMALS; ANTIVIRAL AGENTS; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; FEMALE; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; MICE; MICE, INBRED HRS;

EID: 0029866583     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/0166-3542(96)80225-7     Document Type: Article

References (9)

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