Primate renal transplants using immunotoxin

Surgery

Volumn 124, Issue 2, 1998, Pages 438-447

  Knechtle, S J ^a   Fechner J H , Jr ^a   Dong, Y ^a   Stavrou, S ^a   Neville D M , Jr ^a   Oberley, T ^a   Buckley, P ^a   Armstrong, N ^a   Rusterholz, K ^a   Hong, X ^a   Tsuchida, M ^a   Hamawy, M M ^a   Bartlett, S T ^a   Haisch, C E ^a   Deierhoi, M H ^a   Flye, M W ^a  

^a University of Wisconsin Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOTOXIN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FLOW CYTOMETRY; GRAFT SURVIVAL; IMMUNE RESPONSE; KIDNEY ALLOGRAFT; KIDNEY TRANSPLANTATION; LYMPHOCYTE SUBPOPULATION; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; T LYMPHOCYTE ACTIVATION;

EID: 0031854601     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6060(98)70151-5     Document Type: Article

References (19)

1. S Strober M Dhillon M Schubert B Holm E Engleman C Benike Acquired immune tolerance to cadaveric renal allografts: a study of three patients treated with total lymphoid irradiation N Engl J Med 321 1989 28 33
2. GV Mazariegos J Reyes IR Marino AJ Demetris B Flynn W Irish Weaning of immunosuppression in liver transplant recipients Transplantation 63 1997 243 249
3. WJ Burlingham AP Grailer JH Fechner Jr S Kusaka M Trucco M Kocova Microchimerism linked to cytotoxic T lymphocyte functional unresponsiveness (clonal anergy) in a tolerant renal transplant recipient Transplantation 59 1995 1147 1155
4. FT Thomas FM Carver MB Foil WH Pryor EW Larkin WR Hall Long-term incompatible kidney survival in outbred higher primates without chronic immunosuppression Ann Surg 198 1983 370 378
5. T Kawai AB Cosimi RB Colvin J Powelson J Eason T Kozlowski Mixed allogeneic chimerism and renal allograft tolerance in cynomolgus monkeys Transplantation 59 1995 256 262
6. AD Kirk DM Harlan NN Armstrong TA Davis Y Dong GS Gray CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates Proc Natl Acad Sci U S A 94 1997 8789 8794
7. SJ Knechtle D Vargo J Fechner Y Zhai J Wang MJ Hanaway FN18-CRM9 immunotoxin promotes tolerance in primate renal allografts Transplantation 63 1997 1 6
8. DM Neville Jr J Scharff K. Srinivasachar In vivo T-cell ablation by holo-immunotoxin directed at human CD3 Proc Natl Acad Sci U S A 89 1992 2585 2589
9. JM Thomas DM Neville JL Contreras DE Eckhoff G Meng AL Lobashevsky Preclinical studies of allograft tolerance in rhesus monkeys: a novel anti-CD3-immunotoxin given peritransplant with donor bone marrow induces operational tolerance to kidney allografts Transplantation 64 1997 124 135
10. JH Fechner Jr DJ Vargo EK Geissler C Graeb J Wang MJ Hanaway Split tolerance induced by immunotoxin in a rhesus monkey allograft model Transplantation 63 1997 1339 1345
11. LA Knapp LF Cadavid ME Eberle SJ Knechtle RE Bontrop DI. Watkins Identification of new mamu-DRB alleles using DGGE and direct sequencing Immunogenetics 45 1997 171 179
12. DM Neville J Scharff HZ Hu K Rigaut J Shiloach W Slingerland A new reagent for the induction of T-cell depletion, anti-CD3-CRM9 J Immunother 19 1996 85 92
13. S Ohkawa K Xu LA Wilson R Montelaro LN Martin M. Murphey-Corb Analysis of envelope glycoprotein-specific antibodies from SIV-infected and gp110-immunized monkeys in ACC and ADCC assays AIDS Res Hum Retroviruses 11 1995 395 403
14. DE Eckhoff JL Contreras PX Wang AL Lobashevsky G Meng Y Jiang Immunologic mechanisms favoring operational transplant tolerance induced by deoxyspergualin in rhesus monkeys given anti-CD3 immunotoxin Transplantation 1998 In press
15. N Armstrong P Buckley T Oberley J Fechner Jr Y Dong X Hong Analysis of primate renal allografts following T cell depletion with anti-CD3-CRM9 Transplantation 1998 In press
16. PJ Morrissey K Charrier S Braddy D Liggitt JD. Watson CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice: disease development is prevented by cotransfer of purified CD4+ T cells J Exp Med 178 1993 237 244
17. +CD7- T cells, a memory subset with preferential interleukin-4 production, after bone marrow transplantation Transplantation 64 1997 1453 1459
18. EC. Halperin Total lymphoid irradiation as an immunosuppressive agent for transplantation and the treatment of ‘autoimmune' disease: a review Clin Radiol 36 1985 125 130
19. CL Mackall TA Fleisher MR Brown MP Andrich CC Chen IM Feuerstein Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy N Engl J Med 332 1995 143 149