β-YAC transgenic mice for studying LCR function

Annals of the New York Academy of Sciences

Volumn 850, Issue , 1998, Pages 28-37

  Peterson, Kenneth R ^a,b   Navas, Patrick A ^a   Stamatoyannopoulos, George ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN;

CONFERENCE PAPER; GENE CONTROL; GENE EXPRESSION; GENE LOCUS; GENE MUTATION; GLOBIN GENE; MOUSE; NONHUMAN; TRANSGENIC MOUSE; YEAST ARTIFICIAL CHROMOSOME;

MUS MUSCULUS;

EID: 0031854076     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1998.tb10459.x     Document Type: Conference Paper

References (24)

1. PETERSON, K. R., C. H. CLEGG, C. HUXLEY, B. M. JOSEPHSON, H. S. HAUGEN, T. FURUKAWA & G. STAMATOYANNOPOULOS. 1993. Transgenic mice containing a 248 kb human β locus yeast artificial chromosome display proper developmental control of human globin genes. Proc. Natl. Acad. Sci. USA 90: 7593-7597.
2. GAENSLER, K. M., M. KITAMURA & Y. W. KAN. 1993. Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human β-globin locus in transgenic mice. Proc. Natl. Acad. Sci. USA 90: 11,381-11,385.
3. PETERSON, K. R., Q. LI, C. H. CLEGG, T. FURUKAWA, P. A. NAVAS, E. J. NORTON, T. G. KIMBROUGH & G. STAMATOYANNOPOULOS. 1995. Use of yeast artificial chromosomes (YACs) in studies of mammalian development: Production of β-globin locus YAC mice carrying human globin developmental mutants. Proc. Natl. Acad. Sci. USA 92: 5655-5659.
4. PETERSON, K. R., C. H. CLEGG, Q. LI, P. A. NAVAS, E. J. NORTON, K. A. LEPPIG & G. STAMATOYANNOPOULOS. 1995. Analysis of hemoglobin switching in transgenic mice using β-globin locus yeast artificial chromosomes. In Hemoglobin Switching. G. Stamatoyannopoulos, Ed.: 45-58. Intercept, Ltd. Andover, U.K.
5. PETERSON, K. R., C. H. CLEGG, P. A. NAVAS, E. J. NORTON, T. G. KIMBROUGH & G. STAMATOYANNOPOULOS. 1996. Effect of deletion of 5′HS3 or 5′HS2 of the human β-globin locus control region on the developmental regulation of globin gene expression in β-globin locus yeast artificial chromosome transgenic mice. Proc. Natl. Acad. Sci. USA 93: 6605-6609.
6. NEMETH, A. H., N. HUNTER, M. P. COLEMAN, R. H. BORTS, E. J. Louis & K. E. DAVIES. 1993. Rescue of a single yeast artificial chromosome from a cotransformation event utilizing segregation at meiosis. GATA 10: 123-127.
7. HUGERAT, Y., F. SPENCER, D. ZENVIRTH & G. SIMCHEN. 1994. A versatile method for efficient YAC transfer between any two strains. Genomics 22: 108-117.
8. SPENCER, F., Y. HUGERAT, G. SIMCHEM, O. HURKO, C. CONNELLY & P. HIETER. 1994. Yeast kar1 mutants provide an effective method for YAC transfer to new hosts. Genomics 22: 118-126.
9. SPENCER, F. & G. SIMCHEN. 1996. Transfer of YAC clones to new yeast hosts. In Methods in Molecular Biology, Vol. 54: YAC Protocols. D. Markie, Ed.: 239-252. Humana Press. Totowa, NJ.
10. GNIRKE, A., C. HUXLEY, K. PETERSON & M. V. OLSON. 1993. Microinjection of intact 200- to 500-kb fragments of YAC DNA into mammalian cells. Genomics 15: 659-667.
11. PETERSON, K. R., C. H. CLEGG, Q. LI & G. STAMATOYANNOPOULOS. 1997. Production of transgenic mice with yeast artificial chromosomes. Trends Genet. 13: 61-66.
12. PETERSON, K. R. 1997. Production and analysis of transgenic mice containing yeast artificial chromosomes. In Genetic Engineering, Principles and Methods, Vol. 19. J. K. Setlow, Ed.: 235-255. Plenum Press. New York, NY.
13. ROTHSTEIN, R. 1995. Targeting, disruption, replacement, and allele rescue: Integrative DNA transformation in yeast. In Methods in Enzymology, Vol. 194: Guide to Yeast Genetics and Molecular Biology. C. Guthrie & G. R. Fink, Eds.: 281-301. Academic Press. San Diego, CA.
14. DUFF, K. & C. HUXLEY. 1996. Targeting mutations to YACs by homologous recombination. In Methods in Molecular Biology, Vol. 54. YAC Protocols. D. Markie, Ed.: 187-198. Humana Press. Totowa, NJ.
15. MCCORMICK, S. P. A., K. R. PETERSON, R. E. HAMMER, C. H. CLEGG & S. G. YOUNG. 1996. Generation of transgenic mice from yeast artificial chromosome DNA modified by gene targeting. Trends Cardiovasc. Med. 6: 16-24.
16. nd edit. G. STAMATOYANNOPOULOS, A. W. NIENHUIS, P. MAJERUS & H. VARMUS, Eds.: 107-155. W. B. Saunders. Chicago, IL.
17. Aγ-globin gene in Greek hereditary persistence of fetal hemoglobin. Nature 313: 323-325.
18. Aγ-globin gene promoter in Greek hereditary persistence of fetal hemoglobin. Nature 313: 325-326.
19. GAENSLER, K. M. L., M. BURMEISTER, B. H. BROWNSTEIN, P. TAILLON-MILLER & R. M. MEYERS. 1991. Physical mapping of yeast artificial chromosomes containing sequences from the human β-globin gene region. Genomics 10: 976-984.
20. HUG, B. A., R. L. WESSELSCHMIDT, S. FIERING, M. A. BENDER, E. EPNER, M. GROUDINE & T. J. LEY. 1996. Analysis of mice containing a targeted deletion of β-globin locus control region 5′ hypersensitive site 3. Mol. Cell Biol. 16: 2906-2912.
21. BUNGERT, J., U. DAVÉ, K.-C. LIM, K. H. LIEUW, J. A. SHAVIT, Q. LIU & J. D. ENGEL. 1995. Synergistic regulation of human β-globin gene switching by locus control region elements HS3 and HS4. Genes & Dev. 9: 3083-3096.
22. FRASER, P., S. PRUZINA & F. GROSVELD. 1993. Each hypersensitive site of the human β-globin locus control region confers a different developmental pattern of expression to the globin genes. Genes & Dev. 7: 106-113.
23. WIJGERDE, M., F. GROSVELD & P. FRASER. 1995. Transcription complex stability and chromatin dynamics in vivo. Nature 377: 209-213.
24. LI, Q. & J. A. STAMATOYANNOPOULOS. 1994. Position independence and proper developmental control of γ-globin gene expression require both a 5′ locus control region and a downstream sequence element. Mol. Cell. Biol. 14: 6087-6096.