Flow-induced dilation of rat coronary microvessels is attenuated by isoflurane but enchanced by halothane

Anesthesiology

Volumn 89, Issue 1, 1998, Pages 132-142

  Park, Kyung W ^a   Dai, Hai B ^b   Lowenstein, Edward ^b   Sellke, Frank W ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NONE

Author keywords

Endothelium; Myocardial blood flow; Nitric oxide

Indexed keywords

HALOTHANE; INDOMETACIN; ISOFLURANE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANESTHESIA MECHANISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DILATATION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME SYNTHESIS; GENERAL ANESTHESIA; MINIMUM LUNG ALVEOLUS CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANESTHETICS, INHALATION; ANIMALS; CORONARY CIRCULATION; CORONARY VESSELS; FEMALE; HALOTHANE; ISOFLURANE; MALE; RATS; RATS, WISTAR; VASODILATION;

EID: 0031853997     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199807000-00020     Document Type: Article

References (45)

1. Jones CJH, Kuo L, Davis MJ, Chilian WM: Myogenic and flow-dependent control mechanisms in the coronary microcirculation. Basic Res Cardiol 1993; 88:2-10
2. Melkumyants AM, Balashov SA, Khayutin VM: Control of arterial lumen by shear stress on endothelium. News Physiol Sci 1995; 10:204-10
3. Muldoon SM, Hart JL, Bowen KA, Freas W: Attenuation of endothelium-mediated vasodilation by halothan. ANESTHESIOLOGY 1988; 68:31-7
4. Uggeri MJ, Proctor GJ, Johns RA: Halothane, enflurane, and isoflurane attenuate both receptor- and non-receptor-mediated EDRF production in rat thoracic aorta. ANESTHESIOLOGY 1992; 76:1012-7
5. Park KW, Dai HB, Lowenstein E, Darvish A, Sellke FW: Isoflurane and halothane attenuate endothelium-dependent vasodilation in rat coronary microvessels. Anesth Analg 1997; 84:278-84
6. Akata T, Nakashima M, Kodama K, Boyle WA, III, Takahashi S: Effects of volatile anesthetics on acetylcholine-induced relaxation in the rabbit mesenteric resistance artery. ANESTHESIOLOGY 1995; 82:188-204
7. Murray PA, Fehr DM, Chen BB, Rock P, Esther JW, Desai PM, Nyhan DP: Differential effects of general anesthesia on cGMP-mediated pulmonary vasodilation. J Appl Physiol 1992; 73:721-7
8. Sigmon DH, Florentino-Pineda I, Van Dyke RA, Beierwaltes WH: Halothane impairs the hemodynamic influence of endothelium-derived nitric oxide. ANESTHESIOLOGY 1995; 82:135-43
9. Johns RA, Tichotsky A, Muro M, Spaeth JP, Le Cras TD, Rengasamy A: Halothane and isoflurane inhibit endothelium-derived relaxing factor-dependent cyclic guanosine monophosphate accumulation in endothelial cell-vascular smooth muscle co-cultures independent of an effect on guanylyl cyclase activation. ANESTHESIOLOGY 1995; 83:823-34
10. Zuo Z, Tichotsky A, Johns RA: Halothane and isoflurane inhibit vasodilation due to constitutive but not inducible nitric oxide synthase. ANESTHESIOLOGY 1996; 84:1156-65
11. Hart JL, Jing M, Bina S, Freas W, Van Dyke RA, Muldoon SM: Effects of halothane on EDRF/cGMP-mediated vascular smooth muscle relaxations. ANESTHESIOLOGY 1995; 79:323-31
12. Jing M, Bina S, Verma A, Hart JL, Muldoon SM: Effects of halothane and isoflurane on carbon monoxide-induced relaxations in the rat aorta. ANESTHESIOLOGY 1996; 85:347-54
13. Park KW, Dai HB, Lowenstein E, Darvish A, Sellke FW: Heterogeneous vasomotor effect of isoflurane on rabbit coronary microvessels. ANESTHESIOLOGY 1994; 81:1190-7
14. Koller A, Sun D, Kaley G: Role of shear stress and endothelial prostaglandins in flow- and viscosity-induced dilation of arterioles in vitro. Circ Res 1993; 72:1276-84
15. Kuo L, Davis MJ, Chilian WM: Endothelium-dependent, flow-induced dilation of isolated coronary arterioles. Am J Physiol 1990; 259:H1063-70
16. Park KW, Dai HB, Lowenstein E, Sellke FW: Propofol-associated dilation of rat distal coronary arteries is mediated by multiple agents, including endothelium-derived nitric oxide. Anesth Analg 1995; 81:1191-6
17. Chilian WM, Eastham CL, Marcus ML: Microvascular distribution of coronary vascular resistance in beating left ventricle. Am J Physiol 1986; 251:H779-88
18. Vitez TS, White PF, Eger EI II: Effects of hypothermia on halothane MAC and isoflurane MAC in the rat. ANESTHESIOLOGY 1974; 41:80-1
19. Park KW, Dai HB, Lowenstein E, Sellke FW: Vasomotor responses of rat coronary arteries to isoflurane and halothane depend on pre-exposure tone and vessel size. ANESTHESIOLOGY 1995; 83:1323-30
20. Li JM, Hajarizadeh H, La Rosa CA, Rohrer MJ, Vander Salm TJ, Cutler BS: Heparin and protamine stimulate the production of nitric oxide. J Cardiovasc Surg 1996; 37:445-52
21. Tillmanns H, Ikeda S, Hansen H, Sarma JSM, Fauvel J-M, Bing RJ. Microcirculation in the ventricle of the dog and turtle. Circ Res 1974; 34:561-9
22. Meininger GA, Mack CA, Fehr KL, Bohlen HG. Myogenic vasoregulation overrides local metabolic control in resting rat skeletal muscle. Circ Res 1987; 60:861-70
23. Schretzenmayr A: Über kreislaufregulatorische Vorgänge an den großen Arterien bei der Muskelarbeit. Pflügers Arch 1933; 232:743-8
24. Drexler H, Zeiher AM, Wollschlager H. Meinertz T, Just H, Bonzel T: Flow-dependent coronary artery dilatation in humans. Circulation 1989; 80:466-74
25. Pohl U, Holtz J, Busse R, Bassenge E: Crucial role of endothelium in the vasodilator response to increased flow in vivo. Hypertension 1986; 8:37-44
26. Hull SS Jr, Kaiser L, Jaffe MD, Sparks HV Jr: Endothelium-dependent flow-induced dilation of canine femoral and saphenous arteries. Bloodvessels 1986; 23:183-98
27. Bevan JA, Joyce EH, Wellman GC: Flow-dependent dilation in a resistance artery still occurs after endothelium removal. Circ Res 1988; 63:980-5
28. ATP channels in endothelium. Am J Physiol 1995; 269:H541-9
29. Canty JM, Schwanz JS: Nitric oxide mediates flow-dependent epicardial coronary vasodilation to changes in pulse frequency but not mean flow in conscious dogs. Circulation 1994; 89:375-84
30. Shiode N, Morishima N, Nakayama K, Yamagata T, Matsuura H, Kajiyama G: Flow-mediated vasodilation of human epicardial coronary arteries: Effect of inhibition of nitric oxide synthesis. J Am Coll Cardiol 1996; 27:304-10
31. Rubanyi GM, Romero JC, Vanhoutte PM. Flow-induced release of endothelium-derived relaxing factor. Am J Physiol 1986; 250:H1145-9
32. Jia L, Bonaventura C, Bonaventura J, Stamler JS: S-nitrosohaemoglobin: A dynamic activity of blood involved in vascular control. Nature 1996; 380:221-6
33. Griffith TM, Lewis MJ, Newby AC, Henderson AH: Endothelium-derived relaxing factor. J Am Coll Cardiol 1988; 12:797-806
34. Park KW, Dai H, Lowenstein E, Darvish A, Sellke FW: Isoflurane attenuates cAMP-mediated vasodilation in rat microvessels. Circulation 1995; 92(suppl II):II423-7
35. Park KW, Dai HB, Lowenstein E, Sellke FW: Protein kinase C-induced contraction is inhibited by halothane but enhanced by isoflurane in rat coronary arteries. Anesth Analg 1996; 83:286-90
36. Park KW, Dai HB, Lowenstein E, Darvish A, Sellke FW: Oxygen-derived free radicals mediate isoflurane-induced vasoconstriction of rabbit coronary resistance arteries. Anesth Analg 1995; 80:1163-7
37. Loeb AL, O'Brien DK, Longnecker DE: Halothane inhibits bradykinin-stimulated prostacyclin production in endothelial cells. ANESTHESIOLOGY 1994; 81:931-8
38. Lamping KG, Dole WP: Flow-mediated dilation attenuates constriction of large coronary arteries to serotonin. Am J Physiol 1988; 255:H1317-24
39. Cox DA, Vita JA, Treasure CB, Fish RD, Alexander RW, Ganz P, Selwyn AP: Atherosclerosis impairs flow-mediated dilation of coronary arteries in humans. Circulation 1989; 80:458-65
40. Shimokawa H, Kim P, Vanhoutte PM: Endothelium-dependent relaxation to aggregating platelets in isolated basilar arteries of control and hypercholesterolemic pigs. Circ Res 1988; 63:604-12
41. Sellke FW, Shafique T, Schoen FJ, Weintraub RM: Impaired endothelium-dependent coronary microvascular relaxation after cold potassium cardioplegia and reperfusion. J Thorac Cardiovasc Surg 1993; 105:52-8
42. Minamino T, Kurihara H, Takahashi M, Shimada K, Maemura K, Oda H, Ishikawa T, Uchiyama T, Tanzawa K, Yazaki Y: Endothelial-converting enzyme expression in the rat vascular injury model and human coronary atherosclerosis. Circulation 1997; 95:221-30
43. Marshall I, Al-Kazwini SJ, Roberts PM, Shepperson NB, Adams M, Craig RK: Cardiovascular effects of human and rat CGRP compared in the rat and other species. Eur J Pharmacol 1986; 123:207-16
44. Park KW, Dai HB, Lowenstein E, Sellke FW: Steady-state myogenic response of rat coronary microvessels is preserved by isoflurane but not by halothane. Anesth Analg 1996; 82:969-74
45. Park KW, Lowenstein E, Dai HB, Lopez JJ, Stamler A, Simons M, Sellke FW: Direct vasomotor effects of isoflurane in subepicardial resistance vessels from collateral-dependent and normal coronary circulation of pigs. ANESTHESIOLOGY 1996; 85:584-91