Sodium butyrate induces apoptosis and accumulation of ubiquitinated proteins in human breast carcinoma cells

Cell Death and Differentiation

Volumn 5, Issue 4, 1998, Pages 307-312

  Soldatenkov, Viatcheslav A ^a   Prasad, Sarada ^a   Voloshin, Yaroslav ^a   Dritschilo, Anatoly ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Breast carcinoma; Sodium butyrate; Ubiquitin

Indexed keywords

BUTYRIC ACID; DNA FRAGMENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN; UBIQUITIN;

APOPTOSIS; ARTICLE; BREAST CARCINOMA; CELL ADHESION; CHROMATIN; CONJUGATE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN MODIFICATION; STAINING;

MINK CELL FOCUS-FORMING VIRUS;

EID: 0031853024     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400345     Document Type: Article

References (32)

1. Ball E, Karlik CC, Beal CJ, Seville DL, Sparrow JC, Bullard B and Fyrberg EA (1987) Arthrin, a myofibrillar protein of insect flight muscle, is an actin-ubiqurtin conjugate. Cell 51: 221-228
2. Bush H (1984) Ubiquitination of proteins. Methods Enzymol. 106: 238-262
3. Carlson N, Rogers S and Rechsteiner M (1987) Microinjection of ubiquitin: changesin protein degradation in HeLa cell subjected to heat-shock. J Cell Biol 104: 547-555
4. Chen Z, Hagler J, Palombella VJ, Melandri F, Scherer D, Ballard D and Maniatis T (1995) Signal-induced site-specific phosphorylation targets IκBα to the ubiquitin-proteasome pathway. Genes and Dev. 9: 1586-1597
5. Ciechanover A (1994) The ubiquitin-mediated proteolytic pathway: mechanisms of action and cellular physiology. Biol. Chem. Hoppe-Seyler 375: 565-581
6. Delic J, Morange M and Magdelenat H (1993) Ubiquitin pathway involvement in human lymphocyte; -irradiation-induced apoptosis. Molec Cell. Biol. 13: 4875-4883
7. Drexler HCA (1997) Activation of the cell death program by inhibition of proteasome function. Proc Natl. Acad. Sci. USA 94: 855-860
8. Filippovich IV, Sorokina NI, Soldatenkov VA, Alfyerova TM and Trebenok ZA (1988) Effect of the inducers of cellular differentiation and ionizing radiation on thymus lymphocytes: chromatin degradation and programmed cell death. Int. J. Radiat. Biol. 53: 617-628
9. Fornace AJ, Alamo I, Hollander MC and Lamoreaux E (1989) Ubiquitin mRNA is a major stress-induced transcriptin mammalian cells Nucl Acids Res. 17: 1215-1230
10. Goldberg AL (1992) The mechanism and functions of ATP-dependent proteases in bacterial and animal cells. Eur J Biochem. 203. 9-23
11. Grimm LM, Goldberg AL, Poirier GG, Schwartz LM and Osborne B (1996) Proteasomes play an essential role in thymocyte apoptosis. EMBO J 15: 3835-3844
12. Hague A, Manning AM, Hanlon KA, Huschtscha LI, Hart D and Paraskeva C (1993) Sodium butyrate induces apoptosis in human colonic tumor cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer Int J Cancer 55: 498-505
13. Han J, Dionne CA, Kedersha NL and Goldmacher VS (1997) p53 status affects the rate of the onset but not the overall extent of doxorubicin-induced cell death in Rat-1 fibroblasts constiutively expressing c-Myc. Cancer Res 57: 176-182
14. Hochstrasser M (1996) Protein degradation or regulation Ub the judge. Cell 84: 813-815
15. Imajoh-Ohmi S, Kawaguchi T, Sugiyama S, Tanaka K, Omura S and Kikuchi H (1995) Lactacystin, a specific inhibitor of the proteasome, induces apoptosis in human monoblast U937 cells Biochem. Biophys. Res. Commun. 217: 1070-1077
16. Jones ME, Haire M, Kloetzel P, Mykles D and Schwartz LM (1995) Changes in the structure and fuction of the multicatalytic proteinase (proteasome) during programmed cell death in the intersegmental muscles of the hawkmoth, Maduca sexta Dev Biol 169. 436-447
17. Kim TK and Maniatis T (1996) Regulation of interferon-γ-activated STAT1 by the ubiquitin-proteasome pathway. Science 273 1717-1719
18. Kumar S (1995) ICE-like proteases in apoptosis. Trends Biochem. Sci. 20: 198-202
19. Low P, Bussel K, Dawson SP, Billett MA, Mayer RJ and Reynolds SE (1997) Expression of a 26S proteasome ATPase subunit, MS73, in muscles that undergo developmentally programmed cell death, and its control by ecdysteroid hormones in the insect Manduca sexta FEBS Lett. 400: 345-349
20. Mandal M and Kumar R (1996) Bcl-2 expression regulates sodium butyrate-induced apoptosis in human MCF-7 breast cancer cells. Cell Growth Differ. 7: 311-318
21. Maki CG, Huibregtse JM and Howley PM (1996) In vivo ubiquitination and proteasome-mediated degradation of p53. Cancer Res 56: 2649-2654
22. Mayer JR, Arnold J, Laszlo L, Landon M and Lowe J (1991) Ubiquitin in health and disease Biochim Biophys Acta 1089: 141-157
23. O'Farrel PH (1975) High resolution two-dimensional electrophoresis of proteins. J. Biol. Chem 250: 4007-4021
24. Pagano M, Tam SW, Theodoras AM, Beer-Romero P, Del Sal G, Chau V, Yew PR, Draetta GF and Rolfe M (1995) Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27 Science 269: 682-685
25. Saoul R, Fernandez PA, Quiquerez AL, Martinou I, Maki M, Schroter M, Becherer JD, Irmler M, Tschopp J and Martinou JC (1996) Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons. EMBO J 15: 3845-3852
26. Schwartz LM, Kosz L and Kay BK (1990) Gene activation is required for developmentally programmed cell death Proc. Natl. Acad. Sci. USA 87. 6594-6598
27. Schwartz LM, Smith SW, Jones MEE and Osborne BA (1993) Do all programmed cell death occur via apoptosis? Proc. Natl. Acad. Sci USA 90: 980-984
28. Siegelman M, Bond MW, Gallatin WM, John TS, Smith HT, Fried VA and Weissman IL (1986) Cell surface molecule associated with lymphocyte homing is a ubiquitinated branched-chain glycoprotein. Science 231: 823-829
29. Soldatenkov VA, Prasad S, Notario V and Dritschilo A (1995) Radiation-induced apoptosis of Ewing's sarcoma cells: DNA fragmentation and proteolysis of poly (ADP-ribose) polymerase. Cancer Res. 55: 4240-4242
30. Soldatenkov VA and Dritschilo A (1997) Apoptosis of Ewing's sarcoma cells is accompanied by accumulation of ubiquitinated proteins Cancer Res. 57: 3881-3885
31. Wu RS, Kohn KW and Bonner WM (1981) Metabolism of ubiquitinated histones. J. Biol Chem. 256: 5916-5920
32. Wyllie AH, Kerr JFR and Currie AR (1980) Cell death the significance of apoptosis. Int. Rev. Cytol. 68: 251-306